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Cognitive decline is a natural part of aging. However, under some circumstances, this decline is more pronounced than expected, typically due to disorders such as Alzheimer's disease. Early detection of an anomalous decline is crucial, as…
Understanding the biological and behavioral heterogeneity underlying psychiatric disorders is critical for advancing precision diagnosis, treatment, and prevention. This paper addresses the scientific question of how multimodal data,…
Brain disorders in the early and late life of humans potentially share pathological alterations in brain functions. However, the key evidence from neuroimaging data for pathological commonness remains unrevealed. To explore this hypothesis,…
The ageing population trend is correlated with an increased prevalence of acquired cognitive impairments such as dementia. Although there is no cure for dementia, a timely diagnosis helps in obtaining necessary support and appropriate…
The imaging community has increasingly adopted machine learning (ML) methods to provide individualized imaging signatures related to disease diagnosis, prognosis, and response to treatment. Clinical neuroscience and cancer imaging have been…
Alzheimer's disease and Frontotemporal dementia are common forms of neurodegenerative dementia. Behavioral alterations and cognitive impairments are found in the clinical courses of both diseases and their differential diagnosis is…
Frontotemporal dementia and Alzheimer's disease are two common forms of dementia and are easily misdiagnosed as each other due to their similar pattern of clinical symptoms. Differentiating between the two dementia types is crucial for…
Background: The increasing availability of databases containing both magnetic resonance imaging (MRI) and genetic data allows researchers to utilize multimodal data to better understand the characteristics of dementia of Alzheimer's type…
There has been a growing interest in HCI to understand the specific technological needs of people with dementia and supporting them in self-managing daily activities. One of the most difficult challenges to address is supporting the…
Mild Cognitive Impairment (MCI) affects 12-18% of individuals over 60. MCI patients exhibit cognitive dysfunctions without significant daily functional loss. While MCI may progress to dementia, predicting this transition remains a clinical…
Alzheimer's disease is a progressive neurological disorder characterized by cognitive impairment and memory loss. With the increasing aging population, the incidence of AD is continuously rising, making early diagnosis and intervention an…
In the analysis of remote healthcare monitoring data, time series representation learning offers substantial value in uncovering deeper patterns of patient behavior, especially given the fine temporal granularity of the data. In this study,…
Alzheimer's Disease (AD) causes a continuous decline in memory, thinking, and judgment. Traditional diagnoses are usually based on clinical experience, which is limited by some realistic factors. In this paper, we focus on exploiting deep…
Initial hours of hospital admission impact clinical trajectory, but early clinical decisions often suffer due to data paucity. With clustering analysis for vital signs within six hours of admission, patient phenotypes with distinct…
Mild cognitive impairment (MCI) is characterized by subtle changes in cognitive functions, often associated with disruptions in brain connectivity. The present study introduces a novel fine-grained analysis to examine topological…
The automated evaluation of cognitive status utilizing multimedia technologies presents a promising frontier in early dementia diagnosis. However, the development of robust machine learning models for cognitive impairment detection is…
Clinical depression or Major Depressive Disorder (MDD) is a common and serious medical illness. In this paper, a deep recurrent neural network-based framework is presented to detect depression and to predict its severity level from speech.…
Alzheimer's Disease is a neurodegenerative condition characterized by dementia and impairment in neurological function. The study primarily focuses on the individuals above age 40, affecting their memory, behavior, and cognitive processes…
Deficits in working memory, which includes both the ability to learn and to retain information short-term, are a hallmark of many cognitive disorders. Our study analyzes data from a neuroscience experiment on animal subjects, where…
Background: Electrocardiogram (ECG) analysis has emerged as a promising tool for detecting physiological changes linked to non-cardiac disorders. Given the close connection between cardiovascular and neurocognitive health, ECG abnormalities…