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Cardiovascular disease (CVD) risk prediction models are essential for identifying high-risk individuals and guiding preventive actions. However, existing models struggle with the challenges of real-world clinical practice as they…

Deep learning (DL) methods where interpretability is intrinsically considered as part of the model are required to better understand the relationship of clinical and imaging-based attributes with DL outcomes, thus facilitating their use in…

Image and Video Processing · Electrical Eng. & Systems 2022-12-13 Irem Cetin , Maialen Stephens , Oscar Camara , Miguel Angel Gonzalez Ballester

Usually, clinicians assess the correct hemodynamic behavior and fetal well-being during the gestational age thanks to their professional expertise, with the support of some indices defined for Doppler fetal waveforms. Although this approach…

Cardiopulmonary exercise testing (CPET) provides a comprehensive assessment of functional capacity by measuring key physiological variables including oxygen consumption ($VO_2$), carbon dioxide production ($VCO_2$), and pulmonary…

Machine Learning · Computer Science 2025-03-19 Muhammet Alkan , Gruschen Veldtman , Fani Deligianni

Atrial arrhythmia can be categorized into tachycardia, flutter, and fibrillation. Atrial fibrillation is a prevalent heart disease that results in weak and irregular contractions of the atria. It affects millions people worldwide and…

Medical Physics · Physics 2024-02-01 Jiyue He

Ultrasound imaging of the heart (echocardiography) is widely used to diagnose cardiac diseases. However, obtaining an echocardiogram requires an expert sonographer and a high-quality ultrasound imaging device, which are generally only…

Computer Vision and Pattern Recognition · Computer Science 2025-04-18 Andy Dimnaku , Dominic Yurk , Zhiyuan Gao , Arun Padmanabhan , Mandar Aras , Yaser Abu-Mostafa

In this work we propose a low rank approximation of high fidelity finite element simulations by utilizing weights corresponding to areas of high stress levels for an abdominal aortic aneurysm, i.e. a deformed blood vessel. We focus on the…

Numerical Analysis · Mathematics 2023-05-09 Christoph Striegel , Göran Kauermann , Jonas Biehler

Background: Coronary angiography (CAG) is a cornerstone imaging modality for assessing coronary artery disease and guiding interventional treatment decisions. However, in real-world clinical settings, angiographic images are often…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Jingsong Xia , Siqi Wang

Objective: In this review, we aim to provide an analysis of current cardiac ablation techniques, such as radiofrequency ablation (RF), cryoablation, and pulsed-field ablation (PFA), with a focus on the role of computational modeling in…

Mitral regurgitation (MR) is a heart valve disease with potentially fatal consequences that can only be forestalled through timely diagnosis and treatment. Traditional diagnosis methods are expensive, labor-intensive and require clinical…

Image and Video Processing · Electrical Eng. & Systems 2023-10-10 Ke Xiao , Erik Learned-Miller , Evangelos Kalogerakis , James Priest , Madalina Fiterau

A general-purpose computational homogenization framework is proposed for the nonlinear dynamic analysis of membranes exhibiting complex microscale and/or mesoscale heterogeneity characterized by in-plane periodicity that cannot be…

Computational Engineering, Finance, and Science · Computer Science 2021-01-28 Philip Avery , Daniel Z. Huang , Wanli He , Johanna Ehlers , Armen Derkevorkian , Charbel Farhat

Medical imaging is an important tool for the diagnosis and the evaluation of an aortic dissection (AD); a serious condition of the aorta, which could lead to a life-threatening aortic rupture. AD patients need life-long medical monitoring…

Computer Vision and Pattern Recognition · Computer Science 2020-05-07 Alexander Prutsch , Antonio Pepe , Jan Egger

Accurate assessment of intraventricular blood flow is essential for evaluating hemodynamic conditions in patients supported by Left Ventricular Assist Devices (LVADs). However, clinical imaging is either incompatible with LVADs or yields…

Fully immersive virtual reality (VR) has the potential to improve neurosurgical planning. For example, it may offer 3D visualizations of relevant anatomical structures with complex shapes, such as blood vessels and tumors. However, there is…

Human-Computer Interaction · Computer Science 2019-08-15 Lukas D. J. Fiederer , Hisham Alwanni , Martin Völker , Oliver Schnell , Jürgen Beck , Tonio Ball

Computational fluid dynamics (CFD) based simulation of coronary blood flow provides valuable hemodynamic markers, such as pressure gradients, for diagnosing coronary artery disease (CAD). However, CFD is computationally expensive,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Rene Lisasi , Michele Esposito , Chen Zhao

Cardiovascular disease remains a leading global cause of mortality, necessitating accurate risk prediction tools. Traditional methods, such as QRISK and the Framingham heart score, exhibit limitations in their ability to incorporate…

Genomics · Quantitative Biology 2024-02-12 Farnoush Shishehbori , Zainab Awan

Measuring the blood pressure waveform is becoming a more frequently studied area. The development of sensor technologies opens many new ways to be able to measure high-quality signals. The development of such an aim-specific sensor can be…

Medical Physics · Physics 2025-06-06 Attila Répai , Sándor Földi , Péter Sótonyi , György Cserey

Alzheimer's disease is characterised by the spreading of misfolded proteins and progressive structural changes in the brain. Despite significant clinical research, understanding how microscopic protein dynamics translate into macroscopic…

Computational Engineering, Finance, and Science · Computer Science 2026-03-23 A. Vazquez-Palomo , C. Betegón , J. Weickenmeier , E. Martínez-Pañeda

Background. With the rise of highly portable, wireless, and low-cost ultrasound devices and automatic ultrasound acquisition techniques, an automated interpretation method requiring only a limited set of views as input could make…

Image and Video Processing · Electrical Eng. & Systems 2025-04-29 Li-Hsin Cheng , Pablo B. J. Bosch , Rutger F. H. Hofman , Timo B. Brakenhoff , Eline F. Bruggemans , Rob J. van der Geest , Eduard R. Holman

Each year, approximately 300,000 heart valve repair or replacement procedures are performed worldwide, including approximately 70,000 aortic valve replacement surgeries in the United States alone. This paper describes progress in…