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Medical anomaly detection aims to identify abnormal findings using only normal training data, playing a crucial role in health screening and recognizing rare diseases. Reconstruction-based methods, particularly those utilizing autoencoders…

Machine Learning · Computer Science 2024-07-10 Yu Cai , Hao Chen , Kwang-Ting Cheng

Artificial neural networks trained on large, expert-labelled datasets are considered state-of-the-art for a range of medical image recognition tasks. However, categorically labelled datasets are time-consuming to generate and constrain…

Current unsupervised anomaly localization approaches rely on generative models to learn the distribution of normal images, which is later used to identify potential anomalous regions derived from errors on the reconstructed images. However,…

Image and Video Processing · Electrical Eng. & Systems 2022-07-13 Julio Silva-Rodríguez , Valery Naranjo , Jose Dolz

Multimodal magnetic resonance imaging (MRI) provides complementary information for sub-region analysis of brain tumors. Plenty of methods have been proposed for automatic brain tumor segmentation using four common MRI modalities and…

Image and Video Processing · Electrical Eng. & Systems 2023-03-10 Hong Liu , Dong Wei , Donghuan Lu , Jinghan Sun , Liansheng Wang , Yefeng Zheng

Inverse problems often involve matching observational data using a physical model that takes a large number of parameters as input. These problems tend to be under-constrained and require regularization to impose additional structure on the…

Computational Physics · Physics 2019-06-07 Daniel O'Malley , John K. Golden , Velimir V. Vesselinov

Accurate detection of all pathological findings in 3D medical images remains a significant challenge, as supervised models are limited to detecting only the few pathology classes annotated in existing datasets. To address this, we frame…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Mikhail Goncharov , Eugenia Soboleva , Mariia Donskova , Daniil Ignatyev , Mikhail Belyaev , Ivan Oseledets , Marina Munkhoeva , Maxim Panov

In anomaly detection (AD), one seeks to identify whether a test sample is abnormal, given a data set of normal samples. A recent and promising approach to AD relies on deep generative models, such as variational autoencoders (VAEs), for…

Machine Learning · Computer Science 2021-11-05 Tal Daniel , Thanard Kurutach , Aviv Tamar

This paper introduces MuRAD (Musculoskeletal Radiograph Abnormality Detection tool), a tool that can help radiologists automate the detection of abnormalities in musculoskeletal radiographs (bone X-rays). MuRAD utilizes a Convolutional…

Image and Video Processing · Electrical Eng. & Systems 2020-10-26 Goodarz Mehr

Normative modeling is an emerging and promising approach to effectively study disorder heterogeneity in individual participants. In this study, we propose a novel normative modeling method by combining conditional variational autoencoder…

Machine Learning · Computer Science 2022-11-17 Xuetong Wang , Kanhao Zhao , Rong Zhou , Alex Leow , Ricardo Osorio , Yu Zhang , Lifang He

Detecting anomalies in musculoskeletal radiographs is of paramount importance for large-scale screening in the radiology workflow. Supervised deep networks take for granted a large number of annotations by radiologists, which is often…

Computer Vision and Pattern Recognition · Computer Science 2021-02-23 Antoine Spahr , Behzad Bozorgtabar , Jean-Philippe Thiran

Anomaly detection remains a challenging task in neuroimaging when little to no supervision is available and when lesions can be very small or with subtle contrast. Patch-based representation learning has shown powerful representation…

Image and Video Processing · Electrical Eng. & Systems 2023-04-18 Nicolas Pinon , Robin Trombetta , Carole Lartizien

User and Entity Behaviour Analytics (UEBA) is a broad branch of data analytics that attempts to build a normal behavioural profile in order to detect anomalous events. Among the techniques used to detect anomalies, Deep Autoencoders…

Cryptography and Security · Computer Science 2025-10-31 Jose Fuentes , Ines Ortega-Fernandez , Nora M. Villanueva , Marta Sestelo

This study presents Latent Diffusion Autoencoder (LDAE), a novel encoder-decoder diffusion-based framework for efficient and meaningful unsupervised learning in medical imaging, focusing on Alzheimer disease (AD) using brain MR from the…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Gabriele Lozupone , Alessandro Bria , Francesco Fontanella , Frederick J. A. Meijer , Claudio De Stefano , Henkjan Huisman

The detection of anomalous executions is valuable for reducing potential hazards in assistive manipulation. Multimodal sensory signals can be helpful for detecting a wide range of anomalies. However, the fusion of high-dimensional and…

Robotics · Computer Science 2017-11-03 Daehyung Park , Yuuna Hoshi , Charles C. Kemp

This paper looks into the problem of detecting network anomalies by analyzing NetFlow records. While many previous works have used statistical models and machine learning techniques in a supervised way, such solutions have the limitations…

Machine Learning · Computer Science 2019-03-18 Quoc Phong Nguyen , Kar Wai Lim , Dinil Mon Divakaran , Kian Hsiang Low , Mun Choon Chan

In classification problems, supervised machine-learning methods outperform traditional algorithms, thanks to the ability of neural networks to learn complex patterns. However, in two-class classification tasks like anomaly or fraud…

Machine Learning · Computer Science 2022-04-01 Mihai-Cezar Augustin , Vivien Bonvin , Regis Houssou , Efstratios Rappos , Stephan Robert-Nicoud

Reliable and accurate registration of patient-specific brain magnetic resonance imaging (MRI) scans containing pathologies is challenging due to tissue appearance changes. This paper describes our contribution to the Registration of the…

Image and Video Processing · Electrical Eng. & Systems 2022-11-22 Ramy A. Zeineldin , Mohamed E. Karar , Franziska Mathis-Ullrich , Oliver Burgert

The choice of an appropriate bottleneck dimension and the application of effective regularization are both essential for Autoencoders to learn meaningful representations from unlabeled data. In this paper, we introduce a new class of…

Machine Learning · Computer Science 2025-03-26 Jad Mounayer , Sebastian Rodriguez , Chady Ghnatios , Charbel Farhat , Francisco Chinesta

Unsupervised visual anomaly detection conveys practical significance in many scenarios and is a challenging task due to the unbounded definition of anomalies. Moreover, most previous methods are application-specific, and establishing a…

Computer Vision and Pattern Recognition · Computer Science 2022-11-02 Haiming Yao , Xue Wang , Wenyong Yu

Anomaly localization is an important problem in computer vision which involves localizing anomalous regions within images with applications in industrial inspection, surveillance, and medical imaging. This task is challenging due to the…

Computer Vision and Pattern Recognition · Computer Science 2020-07-20 Shashanka Venkataramanan , Kuan-Chuan Peng , Rajat Vikram Singh , Abhijit Mahalanobis