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Early and accurate diagnosis of Alzheimer's disease (AD) and its prodromal period mild cognitive impairment (MCI) is essential for the delayed disease progression and the improved quality of patients'life. The emerging computer-aided…

Image and Video Processing · Electrical Eng. & Systems 2021-07-29 Fan Zhang , Bo Pan , Pengfei Shao , Peng Liu , Shuwei Shen , Peng Yao , Ronald X. Xu

Unsupervised Anomaly Detection (UAD) with incremental training is crucial in industrial manufacturing, as unpredictable defects make obtaining sufficient labeled data infeasible. However, continual learning methods primarily rely on…

Computer Vision and Pattern Recognition · Computer Science 2024-01-03 Jiaqi Liu , Kai Wu , Qiang Nie , Ying Chen , Bin-Bin Gao , Yong Liu , Jinbao Wang , Chengjie Wang , Feng Zheng

Medical segmentation is performed to determine the bounds of regions of interest (ROI) prior to surgery. By allowing the study of growth, structure, and behaviour of the ROI in the planning phase, critical information can be obtained,…

Image and Video Processing · Electrical Eng. & Systems 2020-10-06 Bao Nguyen , Adam Feldman , Sarath Bethapudi , Andrew Jennings , Chris G. Willcocks

Unsupervised anomaly detection (UAD) methods are trained with normal (or healthy) images only, but during testing, they are able to classify normal and abnormal (or disease) images. UAD is an important medical image analysis (MIA) method to…

Image and Video Processing · Electrical Eng. & Systems 2023-08-16 Yu Tian , Fengbei Liu , Guansong Pang , Yuanhong Chen , Yuyuan Liu , Johan W. Verjans , Rajvinder Singh , Gustavo Carneiro

Traditional deep learning models often lack annotated data, especially in cross-domain applications such as anomaly detection, which is critical for early disease diagnosis in medicine and defect detection in industry. To address this…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Wahyu Rahmaniar , Kenji Suzuki

Unsupervised learning can discover various unseen diseases, relying on large-scale unannotated medical images of healthy subjects. Towards this, unsupervised methods reconstruct a single medical image to detect outliers either in the…

Image and Video Processing · Electrical Eng. & Systems 2020-03-18 Changhee Han , Leonardo Rundo , Kohei Murao , Zoltán Ádám Milacski , Kazuki Umemoto , Evis Sala , Hideki Nakayama , Shin'ichi Satoh

Brain age prediction using neuroimaging data has shown great potential as an indicator of overall brain health and successful aging, as well as a disease biomarker. Deep learning models have been established as reliable and efficient brain…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Bruno Machado Pacheco , Victor Hugo Rocha de Oliveira , Augusto Braga Fernandes Antunes , Saulo Domingos de Souza Pedro , Danilo Silva

Alzheimer's disease (AD) is a progressive and incurable neurodegenerative disease which destroys brain cells and causes loss to patient's memory. An early detection can prevent the patient from further damage of the brain cells and hence…

Image and Video Processing · Electrical Eng. & Systems 2021-01-11 Ali Nawaz , Syed Muhammad Anwar , Rehan Liaqat , Javid Iqbal , Ulas Bagci , Muhammad Majid

Intracranial aneurysms are common nowadays and how to detect them intelligently is of great significance in digital health. While most existing deep learning research focused on medical images in a supervised way, we introduce an…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 Di Shao , Xuequan Lu , Xiao Liu

Artificial intelligence is increasingly integrated into radiotherapy workflows, yet such pipelines remain vulnerable to out-of-distribution image data that may introduce unexpected behavior in clinical tasks. Deep learning-based anomaly…

Harnessing the power of deep neural networks in the medical imaging domain is challenging due to the difficulties in acquiring large annotated datasets, especially for rare diseases, which involve high costs, time, and effort for…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Md Mahfuzur Rahman Siddiquee , Jay Shah , Teresa Wu , Catherine Chong , Todd J. Schwedt , Gina Dumkrieger , Simona Nikolova , Baoxin Li

Despite advances in deep learning for estimating brain age from structural MRI data, incorporating functional MRI data is challenging due to its complex structure and the noisy nature of functional connectivity measurements. To address…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Muhammad Usman , Azka Rehman , Abdullah Shahid , Abd Ur Rehman , Sung-Min Gho , Aleum Lee , Tariq M. Khan , Imran Razzak

Medical images used in clinical practice are heterogeneous and not the same quality as scans studied in academic research. Preprocessing breaks down in extreme cases when anatomy, artifacts, or imaging parameters are unusual or protocols…

Image and Video Processing · Electrical Eng. & Systems 2022-08-31 Mostafa Mehdipour Ghazi , Mads Nielsen

Continuous electrocardiogram (ECG) monitoring via wearable devices is vital for early cardiovascular disease detection. However, deploying deep learning models on resource-constrained microcontrollers faces reliability challenges,…

Machine Learning · Computer Science 2026-01-26 Mustafa Fuad Rifet Ibrahim , Maurice Meijer , Alexander Schlaefer , Peer Stelldinger

Early detection is a crucial goal in the study of Alzheimer's Disease (AD). In this work, we describe several techniques to boost the performance of 3D deep convolutional neural networks (CNNs) trained to detect AD using structural brain…

Image and Video Processing · Electrical Eng. & Systems 2020-04-07 Sheng Liu , Chhavi Yadav , Carlos Fernandez-Granda , Narges Razavian

Magnetic resonance imaging~(MRI) have played a crucial role in brain disease diagnosis, with which a range of computer-aided artificial intelligence methods have been proposed. However, the early explorations usually focus on the limited…

Computer Vision and Pattern Recognition · Computer Science 2023-09-14 Jiayu Lei , Lisong Dai , Haoyun Jiang , Chaoyi Wu , Xiaoman Zhang , Yao Zhang , Jiangchao Yao , Weidi Xie , Yanyong Zhang , Yuehua Li , Ya Zhang , Yanfeng Wang

Predicting future brain state from a baseline magnetic resonance image (MRI) is a central challenge in neuroimaging and has important implications for studying neurodegenerative diseases such as Alzheimer's disease (AD). Most existing…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Ali Farki , Elaheh Moradi , Deepika Koundal , Jussi Tohka

Detecting anomalies in brain MRI scans using supervised deep learning methods presents challenges due to anatomical diversity and labor-intensive requirement of pixel-level annotations. Generative models like Denoising Diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Vivek Kumar Trivedi , Bheeshm Sharma , P. Balamurugan

Anomaly detection (AD) aims at detecting abnormal samples that deviate from the expected normal patterns. Generally, it can be trained merely on normal data, without a requirement for abnormal samples, and thereby plays an important role in…

Computer Vision and Pattern Recognition · Computer Science 2025-02-20 Yu Cai , Weiwen Zhang , Hao Chen , Kwang-Ting Cheng

Many anomaly detection approaches, especially deep learning methods, have been recently developed to identify abnormal image morphology by only employing normal images during training. Unfortunately, many prior anomaly detection methods…