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Angiogenesis is the formation of new blood vessels from pre-existing ones in response to chemical signals secreted by, for example, a wound or a tumour. In this paper, we propose a mesoscopic lattice-based model of angiogenesis, in which…

Tissues and Organs · Quantitative Biology 2016-03-02 Fabian Spill , Pilar Guerrero , Tomas Alarcon , Philip K. Maini , Helen M. Byrne

Stochastic dynamical systems arise naturally across nearly all areas of science and engineering. Typically, a dynamical system model is based on some prior knowledge about the underlying dynamics of interest in which probabilistic features…

Computational Engineering, Finance, and Science · Computer Science 2021-09-03 Chao Yin , Xihaier Luo , Ahsan Kareem

Epithelial-Mesenchymal Transition (EMT), and the corresponding reverse process, Mesenchymal-Epithelial Transition (MET), are dynamic and reversible cellular programs orchestrated by many changes at biochemical and morphological levels. A…

Molecular Networks · Quantitative Biology 2019-07-26 Shubham Tripathi , Jianhua Xing , Herbert Levine , Mohit Kumar Jolly

We propose a stochastic dynamic model of migration and economic aggregation in a system of employed (immobile) and unemployed (mobile) agents which respond to local wage gradients. Dependent on the local economic situation, described by a…

adap-org · Physics 2007-05-23 Frank Schweitzer

The spatio-temporal dynamics of a population present one of the most fascinating aspects and challenges for ecological modelling. In this article we review some simple mathematical models, based on one dimensional…

Populations and Evolution · Quantitative Biology 2008-11-18 A. B. Ryabov , B. Blasius

Simulation models are an absolute necessity in the human and social sciences, which can only very exceptionally use experimental science methods to construct their knowledge. Models enable the simulation of social processes by replacing the…

Computers and Society · Computer Science 2020-01-06 J. Raimbault , D. Pumain

We investigate slow non-equilibrium dynamical processes in two-dimensional $q$--state Potts model with both ferromagnetic and $\pm J$ couplings. Dynamical properties are characterized by means of the mean-flipping time distribution. This…

Statistical Mechanics · Physics 2015-03-20 Ezequiel E. Ferrero , Federico Romá , Sebastián Bustingorry , Pablo M. Gleiser

Hysteresis is treated as a history dependent branching, and the use of the classical Preisach model for the analysis of macroeconomic hysteresis is first discussed. Then, a new Preisach-type model is introduced as a macroeconomic…

Theoretical Economics · Economics 2021-11-01 Isaak D. Mayergoyz , Can E. Korman

A key goal of systems biology is the predictive mathematical description of gene regulatory circuits. Different approaches are used such as deterministic and stochastic models, models that describe cell growth and division explicitly or…

Molecular Networks · Quantitative Biology 2012-10-12 Rahul Marathe , Veronika Bierbaum , David Gomez , Stefan Klumpp

Within the framework of the ViSE (Voting in a Stochastic Environment) model, we examine the dynamics in a society, part of which can be considered an elite. The model allows us to analyze the influence of social attitudes, such as…

Physics and Society · Physics 2025-06-23 Yana Tsodikova , Pavel Chebotarev

Cells use genetic switches to shift between alternate stable gene expression states, e.g., to adapt to new environments or to follow a developmental pathway. Conceptually, these stable phenotypes can be considered as attractive states on an…

Molecular Networks · Quantitative Biology 2021-06-18 Michael Assaf , Shay Be'er , Elijah Roberts

Over the past century, nonlinear difference and differential equations have been used to understand conditions for species coexistence. However, these models fail to account for random fluctuations due to demographic and environmental…

Populations and Evolution · Quantitative Biology 2019-02-12 Sebastian J. Schreiber

Dynamic heterogeneity has often been modeled by assuming that a single-particle observable, fluctuating at a molecular scale, is influenced by its coupling to environmental variables fluctuating on a second, perhaps slower, time scale.…

Condensed Matter · Physics 2009-11-07 Gregor Diezemann , Gerald Hinze , Hans Sillescu

We discuss how to use evolutionary game theory (EGT) as a framework for studying how cultural dynamics and structural properties can influence the evolution of norms and behaviors within a society. We provide a brief tutorial on how EGT…

Computers and Society · Computer Science 2017-03-20 Soham De , Dana S. Nau , Michele J. Gelfand

While the use of spatial agent-based and individual-based models has flourished across many scientific disciplines, the complexities these models generate are often difficult to manage and quantify. This research reduces population-driven,…

Physics and Society · Physics 2021-08-24 John C. Stevenson

An heuristic model of the society, as an assembly of weakly interacting individuals, is discussed. The model allows to connect macroscopic phenomena with features of relations between individuals. Addressing to the problem of inequality, a…

Biological Physics · Physics 2023-10-16 Vladimir Pokrovskii

The gap in statistics between multi-variate and time-series analysis can be bridged by using entropy statistics and recent developments in multi-dimensional scaling. For explaining the evolution of the sciences as non-linear dynamics, the…

Digital Libraries · Computer Science 2012-11-13 Loet Leydesdorff

Mathematical modelling and numerical simulations of interaction populations are crucial topics in systems biology. The interactions of ecological models may occur among individuals of the same species or individuals of different species.…

Quantitative Methods · Quantitative Biology 2017-09-04 Sarbaz H. A. Khoshnaw

We study the impact of contact heterogeneity on epidemic dynamics. A system characterized by multiple susceptible populations is considered. The description of the spread of an infectious disease is obtained through the study of a system of…

Physics and Society · Physics 2021-11-11 Andrea Medaglia , Mattia Zanella

Discrete time, spatially extended models play an important role in ecology, modelling population dynamics of species ranging from micro-organisms to birds. An important question is how 'bottom up', individual-based models can be…

Populations and Evolution · Quantitative Biology 2023-01-20 Linnéa Gyllingberg , David J. T. Sumpter , Åke Brännström