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Haptic feedback is the most significant sensory interface following visual cues. Developing thin, flexible surfaces that function as haptic interfaces is important for augmenting virtual reality, wearable devices, robotics and prostheses.…

Modeling membrane interactions with arbitrarily shaped colloidal particles, such as environmental micro- and nanoplastics, at the cell scale remains particularly challenging, owing to the complexity of particle geometries and the need to…

Soft Condensed Matter · Physics 2025-09-15 Didarul Ahasan Redwan , Justin Reicher , Xin Yong

A parametric simulation tool for pixel sensors is presented. A realistic pixel response is simulated purely based on measurement input, without requiring detailed knowledge of the underlying manufacturing process. As such, it provides an…

While computational modeling may help to develop new treatment options for hand and wrist injuries, at present, few models exist. The time and expertise required to develop and use these models is considerable. Moreover, most do not allow…

Quantitative Methods · Quantitative Biology 2025-05-27 Thor E. Andreassen , Taylor P. Trentadue , Andrew R. Thoreson , Kai-Nan An , Sanjeev Kakar , Kristin D. Zhao

Mathematical modelling is a widely used approach to understand and interpret clinical trial data. This modelling typically involves fitting mechanistic mathematical models to data from individual trial participants. Despite the widespread…

We introduce an Active Vertex Model (AVM) for cell-resolution studies of the mechanics of confluent epithelial tissues consisting of tens of thousands of cells, with a level of detail inaccessible to similar methods. The AVM combines the…

Biological Physics · Physics 2016-12-20 Daniel L. Barton , Silke Henkes , Cornelis J. Weijer , Rastko Sknepnek

Physical interactive robotics, ranging from wearable devices to collaborative humanoid robots, require close coordination between mechanical design and control. However, evaluating interactive dynamics is challenging due to complex human…

Robotics · Computer Science 2026-03-11 Chenhui Zuo , Jinhao Xu , Michael Qian Vergnolle , Yanan Sui

Immersed finite element (IFE) methods are a group of long-existing numerical methods for solving interface problems on unfitted meshes. A core argument of the methods is to avoid mesh regeneration procedure when solving moving interface…

Numerical Analysis · Mathematics 2020-05-01 Ruchi Guo

Mathematical Modelling has a long history in developmental biology. Advances in experimental techniques and computational algorithms now permit the development of increasingly more realistic models of organogenesis. In particular, 3D…

Computational Engineering, Finance, and Science · Computer Science 2014-08-08 Zahra Karimaddini , Erkan Unal , Denis Menshykau , Dagmar Iber

A new computer haptics algorithm to be used in general interactive manipulations of deformable virtual objects is presented. In multimodal interactive simulations, haptic feedback computation often comes from contact forces. Subsequently,…

Graphics · Computer Science 2008-12-18 Christian Duriez , Frédéric Dubois , Abderrahmane Kheddar , Claude Andriot

We present SoftSMPL, a learning-based method to model realistic soft-tissue dynamics as a function of body shape and motion. Datasets to learn such task are scarce and expensive to generate, which makes training models prone to overfitting.…

Computer Vision and Pattern Recognition · Computer Science 2020-12-11 Igor Santesteban , Elena Garces , Miguel A. Otaduy , Dan Casas

In medicolegal situations, the consequences of a stabbing incident are described in terms that are qualitative without being quantitative. Here, the mechanical variables involved in knife-tissue penetration events are used to determine the…

Classical Physics · Physics 2008-11-25 Michael D. Gilchrist , Stephen Keenan , Michael Curtis , Mary Cassidy , Greg Byrne , Michel Destrade

Control strategies for robotic needle steering in soft tissues must account for complex interactions between the needle and the tissue to achieve accurate needle tip positioning. Recent findings show faster robotic command rate can improve…

Data-driven approaches to tactile sensing aim to overcome the complexity of accurately modeling contact with soft materials. However, their widespread adoption is impaired by concerns about data efficiency and the capability to generalize…

Robotics · Computer Science 2020-03-06 Carmelo Sferrazza , Thomas Bi , Raffaello D'Andrea

We present a methodical procedure for topology optimization under uncertainty with multi-resolution finite element models. We use our framework in a bi-fidelity setting where a coarse and a fine mesh corresponding to low- and…

Numerical Analysis · Computer Science 2019-04-08 Vahid Keshavarzzadeh , Robert M. Kirby , Akil Narayan

The simulation of morphogenetic problems requires the simultaneous and coupled simulation of signalling and tissue dynamics. A cellular resolution of the tissue domain is important to adequately describe the impact of cell-based events,…

Quantitative Methods · Quantitative Biology 2015-03-29 Simon Tanaka , David Sichau , Dagmar Iber

Parametric optimization is an important product design technique, especially in the context of the modern parametric feature-based CAD paradigm. Realizing its full potential, however, requires a closed loop between CAD and CAE (i.e.,…

Computational Engineering, Finance, and Science · Computer Science 2023-03-28 Ming Li , Chengfeng Lin , Wei Chen , Yusheng Liu , Shuming Gao , Qiang Zou

We propose a method for efficiently coupling the finite element method with atomistic simulations, while using molecular dynamics or kinetic Monte Carlo techniques. Our method can dynamically build an optimized unstructured mesh that…

Computational Engineering, Finance, and Science · Computer Science 2018-05-23 Mihkel Veske , Andreas Kyritsakis , Kristjan Eimre , Vahur Zadin , Alvo Aabloo , Flyura Djurabekova

Safety of medical devices and of their interoperation is an unresolved issue causing severe and sometimes deadly accidents for patients with shocking frequency. Formal methods, particularly in support of highly reusable and provably safe…

Logic in Computer Science · Computer Science 2010-09-23 Mu Sun , José Meseguer

This paper introduces a new Finite Element biomechanical model of the human face, which has been developed to be integrated into a simulator for plastic and maxillo-facial surgery. The idea is to be able to predict, from an aesthetic and…

Medical Physics · Physics 2007-05-23 Matthieu Chabanas , Yohan Payan