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Deep learning models are notoriously vulnerable to imperceptible perturbations. Most existing research centers on adversarial robustness (AR), which evaluates models under worst-case scenarios by examining the existence of deterministic…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Yi Zhang , Zheng Wang , Zhen Chen , Wenjie Ruan , Qing Guo , Siddartha Khastgir , Carsten Maple , Xingyu Zhao

Recent breakthroughs in self-supervised learning have enabled the use of large unlabeled datasets to train visual foundation models that can generalize to a variety of downstream tasks. While this training paradigm is well suited for the…

Digital pathology is a tool of rapidly evolving importance within the discipline of pathology. Whole slide imaging promises numerous advantages; however, adoption is limited by challenges in ease of use and speed of high-quality image…

Graphics · Computer Science 2025-04-24 Ryan Erik Landvater , Ulysses Balis

From self-supervised, vision-only models to contrastive visual-language frameworks, computational pathology has rapidly evolved in recent years. Generative AI "co-pilots" now demonstrate the ability to mine subtle, sub-visual tissue cues…

Computer Vision and Pattern Recognition · Computer Science 2025-02-13 Mohsin Bilal , Aadam , Manahil Raza , Youssef Altherwy , Anas Alsuhaibani , Abdulrahman Abduljabbar , Fahdah Almarshad , Paul Golding , Nasir Rajpoot

Deep learning-based diagnostic systems have demonstrated potential in skin disease diagnosis. However, their performance can easily degrade on test domains due to distribution shifts caused by input-level corruptions, such as imaging…

Image and Video Processing · Electrical Eng. & Systems 2024-05-21 Ming Hu , Siyuan Yan , Peng Xia , Feilong Tang , Wenxue Li , Peibo Duan , Lin Zhang , Zongyuan Ge

In computational pathology, several foundation models have recently emerged and demonstrated enhanced learning capability for analyzing pathology images. However, adapting these models to various downstream tasks remains challenging,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Jeaung Lee , Jeewoo Lim , Keunho Byeon , Jin Tae Kwak

Electrical Impedance Tomography (EIT) is a powerful imaging technique with diverse applications, e.g., medical diagnosis, industrial monitoring, and environmental studies. The EIT inverse problem is about inferring the internal conductivity…

Machine Learning · Computer Science 2023-10-31 Derick Nganyu Tanyu , Jianfeng Ning , Andreas Hauptmann , Bangti Jin , Peter Maass

Recent work introduced the epinet as a new approach to uncertainty modeling in deep learning. An epinet is a small neural network added to traditional neural networks, which, together, can produce predictive distributions. In particular,…

Machine Learning · Computer Science 2022-07-04 Xiuyuan Lu , Ian Osband , Seyed Mohammad Asghari , Sven Gowal , Vikranth Dwaracherla , Zheng Wen , Benjamin Van Roy

Random testing (RT) is a black-box software testing technique that tests programs by generating random test inputs. It is a widely used technique for software quality assurance, but there has been much debate by practitioners concerning its…

Software Engineering · Computer Science 2019-10-01 Jinfu Chen , Hilary Ackah-Arthur , Chengying Mao , Patrick Kwaku Kudjo

Noisy data and the similarity in the ocular appearances caused by different ophthalmic pathologies pose significant challenges for an automated expert system to accurately detect retinal diseases. In addition, the lack of knowledge…

Image and Video Processing · Electrical Eng. & Systems 2021-10-20 Sharif Amit Kamran , Alireza Tavakkoli , Stewart Lee Zuckerbrod

The field of digital pathology has seen a proliferation of deep learning models in recent years. Despite substantial progress, it remains rare for other researchers and pathologists to be able to access models published in the literature…

Tissues and Organs · Quantitative Biology 2024-01-15 Jakub R. Kaczmarzyk , Alan O'Callaghan , Fiona Inglis , Tahsin Kurc , Rajarsi Gupta , Erich Bremer , Peter Bankhead , Joel H. Saltz

It has been shown that the majority of existing adversarial defense methods achieve robustness at the cost of sacrificing prediction accuracy. The undesirable severe drop in accuracy adversely affects the reliability of machine learning…

Cryptography and Security · Computer Science 2020-11-05 Jiawei Du , Hanshu Yan , Vincent Y. F. Tan , Joey Tianyi Zhou , Rick Siow Mong Goh , Jiashi Feng

Deep learning in digital pathology brings intelligence and automation as substantial enhancements to pathological analysis, the gold standard of clinical diagnosis. However, multiple steps from tissue preparation to slide imaging introduce…

Image and Video Processing · Electrical Eng. & Systems 2023-11-01 Peixiang Huang , Songtao Zhang , Yulu Gan , Rui Xu , Rongqi Zhu , Wenkang Qin , Limei Guo , Shan Jiang , Lin Luo

As deep learning models continue to advance and are increasingly utilized in real-world systems, the issue of robustness remains a major challenge. Existing certified training methods produce models that achieve high provable robustness…

Machine Learning · Computer Science 2023-07-26 Zhakshylyk Nurlanov , Frank R. Schmidt , Florian Bernard

The microscopic examination of surgical tissue remains a cornerstone of disease classification but relies on subjective interpretations and access to highly specialized experts, which can compromise accuracy and clinical care. While…

Automated pavement distresses detection using road images remains a challenging topic in the computer vision research community. Recent developments in deep learning has led to considerable research activity directed towards improving the…

Computer Vision and Pattern Recognition · Computer Science 2020-04-29 Hamed Majidifard , Peng Jin , Yaw Adu-Gyamfi , William G. Buttlar

The escalating global cancer burden underscores the critical need for precise diagnostic tools in oncology. This research employs deep learning to enhance lesion segmentation in PET/CT imaging, utilizing a dataset of 900 whole-body…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Jiayi Liu , Qiaoyi Xue , Youdan Feng , Tianming Xu , Kaixin Shen , Chuyun Shen , Yuhang Shi

Reproducibility of AI models on biomedical data still stays as a major concern for their acceptance into the clinical practice. Initiatives for reproducibility in the development of predictive biomarkers as the MAQC Consortium already…

Quantitative Methods · Quantitative Biology 2020-11-18 Nicole Bussola , Alessia Marcolini , Valerio Maggio , Giuseppe Jurman , Cesare Furlanello

In deep learning applications, robustness measures the ability of neural models that handle slight changes in input data, which could lead to potential safety hazards, especially in safety-critical applications. Pre-deployment assessment of…

Software Engineering · Computer Science 2024-04-26 Wenchuan Mu , Kwan Hui Lim

Artificial intelligence (AI) has transformed digital pathology by enabling biomarker prediction from high-resolution whole-slide images (WSIs). However, current methods are computationally inefficient, processing thousands of redundant…

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