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Nascent quantum computers motivate the exploration of quantum many-body systems in nontraditional scenarios. For example, it has become natural to explore the dynamics of systems evolving under both unitary evolution and measurement. Such…

Statistical Mechanics · Physics 2024-03-15 Nicholas O'Dea , Alan Morningstar , Sarang Gopalakrishnan , Vedika Khemani

We propose a systematic methodology to identify the topological phase transition through a self-supervised machine learning model, which is trained to correlate system parameters to the non-local observables in time-of-flight experiments of…

Quantum Gases · Physics 2021-09-01 Chi-Ting Ho , Daw-Wei Wang

Quantum computing promises to revolutionize several scientific and technological domains through fundamentally new ways of processing information. Among its most compelling applications is digital quantum simulation, where quantum computers…

Quantum Physics · Physics 2026-02-05 Laurin E. Fischer

Discrete combinatorial optimization consists in finding the optimal configuration that minimizes a given discrete objective function. An interpretation of such a function as the energy of a classical system allows us to reduce the…

Quantum Physics · Physics 2015-06-22 Sergio Boixo , Gerardo Ortiz , Rolando Somma

Understanding the dynamic behavior of biomolecules is fundamental to elucidating biological function and facilitating drug discovery. While Molecular Dynamics (MD) simulations provide a rigorous physical basis for studying these dynamics,…

Biomolecules · Quantitative Biology 2026-03-19 Liang Shi , Jiarui Lu , Junqi Liu , Chence Shi , Zhi Yang , Jian Tang

Quantum computers promise to perform computations beyond the reach of modern computers with profound implications for scientific research. Due to remarkable technological advances, small scale devices are now becoming available for use. One…

Strongly Correlated Electrons · Physics 2022-05-20 Adam Smith , Bernhard Jobst , Andrew G. Green , Frank Pollmann

The application of molecular dynamics (MD) simulations to quasistatic loading is severely limited by the large separation between atomic vibration timescales and experimentally relevant deformation rates. In this work we employ the…

Materials Science · Physics 2026-05-27 Sarthok Kumar Baruah , Sabyasachi Chatterjee , Amit Acharya , Gerald J. Wang

Characterization of transient intermediate or transition states is crucial for the description of biomolecular folding pathways, which is however difficult in both experiments and computer simulations. Such transient states are typically of…

Biomolecules · Quantitative Biology 2009-11-13 Yuan Yao , Jian Sun , Xuhui Huang , Gregory R. Bowman , Gurjeet Singh , Michael Lesnick

The quest for real-time dynamic optimization solutions in the process industry represents a formidable computational challenge, particularly within the realm of applications like model-predictive control, where rapid and reliable…

Optimization and Control · Mathematics 2024-04-29 Dennis Michael Nenno , Adrian Caspari

This thesis is based upon the work I have done during my PhD candidature at Macquarie University. In this work we develop quantum technologies that are directed towards realising a quantum computer. Specifically, we have made many…

Quantum Physics · Physics 2017-03-17 Keith R. Motes

Stochastic simulation has been a powerful tool for studying the dynamics of gene regulatory networks, particularly in terms of understanding how cell-phenotype stability and fate-transitions are impacted by noisy gene expression. However,…

Molecular Networks · Quantitative Biology 2018-09-05 Margaret J. Tse , Brian K. Chu , Elizabeth L. Read

We time-evolve a translationally invariant quantum state on the Quantinuum H1-1 trapped-ion quantum processor, studying the dynamical quantum phase transition of the transverse field Ising model. This physics requires a delicate…

Distributed quantum computation is often proposed to increase the scalability of quantum hardware, as it reduces cooperative noise and requisite connectivity by sharing quantum information between distant quantum devices. However, such…

Quantum Physics · Physics 2023-09-13 Abigail McClain Gomez , Taylor L. Patti , Anima Anandkumar , Susanne F. Yelin

Molecular dynamics (MD) simulations present a data-mining challenge, given that they can generate a considerable amount of data but often rely on limited or biased human interpretation to examine their information content. By not asking the…

Materials Science · Physics 2025-07-31 Fabrice Roncoroni , Ana Sanz-Matias , Siddharth Sundararaman , David Prendergast

The simulation of high-energy physics collision events is a key element for data analysis at present and future particle accelerators. The comparison of simulation predictions to data allows looking for rare deviations that can be due to…

High Energy Physics - Experiment · Physics 2024-07-16 Francesco Vaselli , Filippo Cattafesta , Patrick Asenov , Andrea Rizzi

Understanding molecular structure, dynamics, and reactivity requires bridging processes that occur across widely separated time scales. Conventional molecular dynamics simulations provide atomistic resolution, but their femtosecond time…

Chemical Physics · Physics 2025-10-10 Juan Viguera Diez , Mathias Schreiner , Simon Olsson

Molecular dynamics (MD) simulations are widely used to study large-scale molecular systems. HPC systems are ideal platforms to run these studies, however, reaching the necessary simulation timescale to detect rare processes is challenging,…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-08-22 Tu Mai Anh Do , Loïc Pottier , Rafael Ferreira da Silva , Frédéric Suter , Silvina Caíno-Lores , Michela Taufer , Ewa Deelman

Continuous diffusion models have demonstrated remarkable performance in data generation across various domains, yet their efficiency remains constrained by two critical limitations: (1) the local adjacency structure of the forward Markov…

Machine Learning · Statistics 2025-05-29 Xunpeng Huang , Yingyu Lin , Nikki Lijing Kuang , Hanze Dong , Difan Zou , Yian Ma , Tong Zhang

Using a coarse molecular-dynamics (CMD) approach with an appropriate choice of coarse variable (order parameter), we map the underlying effective free-energy landscape for the melting of a crystalline solid. Implementation of this approach…

Materials Science · Physics 2009-11-11 Miguel A. Amat , Ioannis G. Kevrekidis , Dimitrios Maroudas

We develop and implement a method for modeling decoherence processes on an N-dimensional quantum system that requires only an $N^2$-dimensional quantum environment and random classical fields. This model offers the advantage that it may be…

Quantum Physics · Physics 2009-11-10 G. Teklemariam , E. M. Fortunato , C. C. Lopez , J. Emerson , J. P. Paz , T. F. Havel , D. G. Cory