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In real-life applications, machine learning models often face scenarios where there is a change in data distribution between training and test domains. When the aim is to make predictions on distributions different from those seen at…

Machine Learning · Computer Science 2021-11-04 Lucas Mansilla , Rodrigo Echeveste , Diego H. Milone , Enzo Ferrante

Clinical machine learning models experience significantly degraded performance in datasets not seen during training, e.g., new hospitals or populations. Recent developments in domain generalization offer a promising solution to this problem…

Machine Learning · Computer Science 2021-04-16 Haoran Zhang , Natalie Dullerud , Laleh Seyyed-Kalantari , Quaid Morris , Shalmali Joshi , Marzyeh Ghassemi

The rapid development of deep learning, a family of machine learning techniques, has spurred much interest in its application to medical imaging problems. Here, we develop a deep learning algorithm that can accurately detect breast cancer…

Computer Vision and Pattern Recognition · Computer Science 2019-10-08 Li Shen , Laurie R. Margolies , Joseph H. Rothstein , Eugene Fluder , Russell B. McBride , Weiva Sieh

Mammography-based screening has helped reduce the breast cancer mortality rate, but has also been associated with potential harms due to low specificity, leading to unnecessary exams or procedures, and low sensitivity. Digital breast…

Computer Vision and Pattern Recognition · Computer Science 2020-01-24 Sadanand Singh , Thomas Paul Matthews , Meet Shah , Brent Mombourquette , Trevor Tsue , Aaron Long , Ranya Almohsen , Stefano Pedemonte , Jason Su

Domain generalization aims at training machine learning models to perform robustly across different and unseen domains. Several recent methods use multiple datasets to train models to extract domain-invariant features, hoping to generalize…

Machine Learning · Computer Science 2021-05-19 Mattia Segu , Alessio Tonioni , Federico Tombari

Despite much progress being made in the field of object recognition with the advances of deep learning, there are still several factors negatively affecting the performance of deep learning models. Domain shift is one of these factors and…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Kaiyu Guo , Brian Lovell

This paper investigates the impact of breast density distribution on the generalization performance of deep-learning models on mammography images using the VinDr-Mammo dataset. We explore the use of domain adaptation techniques,…

Computer Vision and Pattern Recognition · Computer Science 2023-06-13 Huy T. Nguyen , Thinh B. Lam , Quan D. D. Tran , Minh T. Nguyen , Dat T. Chung , Vinh Q. Dinh

Objective: When training machine learning models, we often assume that the training data and evaluation data are sampled from the same distribution. However, this assumption is violated when the model is evaluated on another unseen but…

Computer Vision and Pattern Recognition · Computer Science 2020-11-13 Theekshana Dissanayake , Tharindu Fernando , Simon Denman , Houman Ghaemmaghami , Sridha Sridharan , Clinton Fookes

Machine learning and computer vision methods are showing good performance in medical imagery analysis. Yetonly a few applications are now in clinical use and one of the reasons for that is poor transferability of themodels to data from…

Image and Video Processing · Electrical Eng. & Systems 2020-10-15 Ekaterina Kondrateva , Marina Pominova , Elena Popova , Maxim Sharaev , Alexander Bernstein , Evgeny Burnaev

Deep learning models have exhibited exceptional effectiveness in Computational Pathology (CPath) by tackling intricate tasks across an array of histology image analysis applications. Nevertheless, the presence of out-of-distribution data…

Image and Video Processing · Electrical Eng. & Systems 2023-10-31 Mostafa Jahanifar , Manahil Raza , Kesi Xu , Trinh Vuong , Rob Jewsbury , Adam Shephard , Neda Zamanitajeddin , Jin Tae Kwak , Shan E Ahmed Raza , Fayyaz Minhas , Nasir Rajpoot

The performance of existing underwater object detection methods degrades seriously when facing domain shift caused by complicated underwater environments. Due to the limitation of the number of domains in the dataset, deep detectors easily…

Computer Vision and Pattern Recognition · Computer Science 2023-01-19 Yang Chen , Pinhao Song , Hong Liu , Linhui Dai , Xiaochuan Zhang , Runwei Ding , Shengquan Li

Current machine learning methods for medical image analysis primarily focus on developing models tailored for their specific tasks, utilizing data within their target domain. These specialized models tend to be data-hungry and often exhibit…

Image and Video Processing · Electrical Eng. & Systems 2024-07-08 Ece Ozkan , Xavier Boix

For deep learning applications, the massive data development (e.g., collecting, labeling), which is an essential process in building practical applications, still incurs seriously high costs. In this work, we propose an effective data…

Machine Learning · Statistics 2019-12-30 Shin'ya Yamaguchi , Sekitoshi Kanai , Takeharu Eda

Supervised deep learning models often achieve excellent performance within their training distribution but struggle to generalize beyond it. In cancer histopathology, for example, a convolutional neural network (CNN) may classify cancer…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Justin Cheung , Samuel Savine , Calvin Nguyen , Lin Lu , Alhassan S. Yasin

Domain shift is a significant problem in histopathology. There can be large differences in data characteristics of whole-slide images between medical centers and scanners, making generalization of deep learning to unseen data difficult. To…

Computer Vision and Pattern Recognition · Computer Science 2019-09-27 Karin Stacke , Gabriel Eilertsen , Jonas Unger , Claes Lundström

Mammography, an X-ray-based imaging technique, remains central to the early detection of breast cancer. Recent advances in artificial intelligence have enabled increasingly sophisticated computer-aided diagnostic methods, evolving from…

Image and Video Processing · Electrical Eng. & Systems 2025-10-09 Daniel G. P. Petrini , Hae Yong Kim

Medical image artificial intelligence models often achieve strong performance in single-center or single-device settings, yet their effectiveness frequently deteriorates in real-world cross-center deployment due to domain shift, limiting…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Jingsong Xia , Siqi Wang

A major limitation in applying deep learning to artificial intelligence (AI) systems is the scarcity of high-quality curated datasets. We investigate strong augmentation based self-supervised learning (SSL) techniques to address this…

Image and Video Processing · Electrical Eng. & Systems 2022-03-18 John D. Miller , Vignesh A. Arasu , Albert X. Pu , Laurie R. Margolies , Weiva Sieh , Li Shen

This paper provides a critical review of the literature on deep learning applications in breast tumor diagnosis using ultrasound and mammography images. It also summarizes recent advances in computer-aided diagnosis (CAD) systems, which…

Image and Video Processing · Electrical Eng. & Systems 2020-10-05 Yuliana Jiménez-Gaona , María José Rodríguez-Álvarez , Vasudevan Lakshminarayanan

Deep learning has revolutionized neuroimage analysis by delivering unprecedented speed and accuracy. However, the narrow scope of many training datasets constrains model robustness and generalizability. This challenge is particularly acute…

Image and Video Processing · Electrical Eng. & Systems 2025-12-08 Malte Hoffmann