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Scientific progress is driven by the deliberate articulation of what remains unknown. This study investigates the ability of large language models (LLMs) to identify research knowledge gaps in the biomedical literature. We define two…

Computation and Language · Computer Science 2025-10-30 Nourah M Salem , Elizabeth White , Michael Bada , Lawrence Hunter

Knowledge graph reasoning is pivotal in various domains such as data mining, artificial intelligence, the Web, and social sciences. These knowledge graphs function as comprehensive repositories of human knowledge, facilitating the inference…

Artificial Intelligence · Computer Science 2024-12-17 Lihui Liu , Zihao Wang , Hanghang Tong

With the advancements in computer technology, there is a rapid development of intelligent systems to understand the complex relationships in data to make predictions and classifications. Artificail Intelligence based framework is rapidly…

Machine Learning · Computer Science 2021-07-30 G Jignesh Chowdary , Suganya G , Premalatha M , Asnath Victy Phamila Y , Karunamurthy K

With the rapid growth of research publications, empowering scientists to keep oversight over the scientific progress is of paramount importance. In this regard, the Leaderboards facet of information organization provides an overview on the…

Computation and Language · Computer Science 2021-09-28 Salomon Kabongo , Jennifer D'Souza , Sören Auer

This paper describes a new kind of knowledge representation and mining system which we are calling the Semantic Knowledge Graph. At its heart, the Semantic Knowledge Graph leverages an inverted index, along with a complementary uninverted…

Information Retrieval · Computer Science 2016-09-06 Trey Grainger , Khalifeh AlJadda , Mohammed Korayem , Andries Smith

Background: Conventional electrocardiogram (ECG) analysis faces a persistent dichotomy: expert-driven features ensure interpretability but lack sensitivity to latent patterns, while deep learning offers high accuracy but functions as a…

Quantitative Methods · Quantitative Biology 2026-01-23 Deyun Zhang , Jun Li , Shijia Geng , Yue Wang , Shijie Chen , Sumei Fan , Qinghao Zha , Shenda Hong

Large language models (LLMs) are rapidly transforming various domains, including biomedicine and healthcare, and demonstrate remarkable potential from scientific research to new drug discovery. Graph-based retrieval-augmented generation…

Quantitative Methods · Quantitative Biology 2025-11-14 Guofeng Meng , Li Shen , Qiuyan Zhong , Wei Wang , Haizhou Zhang , Xiaozhen Wang

Screening patients for clinical trial eligibility remains a manual, time-consuming, and resource-intensive process. We present a secure, scalable proof-of-concept system for Artificial Intelligence (AI)-augmented patient-trial matching that…

The scientific literature is growing faster than ever. Finding an expert in a particular scientific domain has never been as hard as today because of the increasing amount of publications and because of the ever growing diversity of…

Information Retrieval · Computer Science 2020-04-09 Robin Brochier , Antoine Gourru , Adrien Guille , Julien Velcin

Verification of biomedical claims is critical for healthcare decision-making, public health policy and scientific research. We present an interactive biomedical claim verification system by integrating LLMs, transparent model explanations,…

Human-Computer Interaction · Computer Science 2025-03-03 Siting Liang , Daniel Sonntag

We explore the potential for combining generative AI with grammar-based visualizations for biomedical data discovery. In our prototype, we use a multi-agent system to generate visualization specifications and apply filters. These…

Human-Computer Interaction · Computer Science 2025-09-23 Devin Lange , Shanghua Gao , Pengwei Sui , Austen Money , Priya Misner , Marinka Zitnik , Nils Gehlenborg

Knowledge mining is the process of deriving new and useful knowledge from vast volumes of data and background knowledge. Modern healthcare organizations regularly generate huge amount of electronic data stored in the databases. These data…

Logic in Computer Science · Computer Science 2011-07-26 Nittaya Kerdprasop , Kittisak Kerdprasop

Discovery gene-disease links is important in biology and medicine areas, enabling disease identification and drug repurposing. Machine learning approaches accelerate this process by leveraging biological knowledge represented in ontologies…

Machine Learning · Computer Science 2025-04-14 Catarina Canastra , Cátia Pesquita

The landscape of science and technology is characterized by its dynamic and evolving nature, constantly reshaped by new discoveries, innovations, and paradigm shifts. Moreover, science is undergoing a remarkable shift towards increasing…

Information Retrieval · Computer Science 2025-12-22 Ashkan Ebadi , Alain Auger , Yvan Gauthier

The effectiveness of artificial intelligence (AI) in healthcare is significantly hindered by unstructured clinical documentation, which results in noisy, inconsistent, and logically fragmented training data. To address this challenge, we…

Machine Learning · Computer Science 2025-10-21 Dun Liu , Qin Pang , Guangai Liu , Hongyu Mou , Jipeng Fan , Yiming Miao , Pin-Han Ho , Limei Peng

An artificial intelligence (AI) model can be viewed as a function that maps inputs to outputs in high-dimensional spaces. Once designed and well trained, the AI model is applied for inference. However, even optimized AI models can produce…

Artificial Intelligence · Computer Science 2026-02-27 Sha Hu

The exponential growth of scientific knowledge has created significant barriers to cross-disciplinary knowledge discovery, synthesis and research collaboration. In response to this challenge, we present BioSage, a novel compound AI…

A promising application of AI to healthcare is the retrieval of information from electronic health records (EHRs), e.g. to aid clinicians in finding relevant information for a consultation or to recruit suitable patients for a study. This…

Computation and Language · Computer Science 2020-11-02 Claudia Schulz , Josh Levy-Kramer , Camille Van Assel , Miklos Kepes , Nils Hammerla

The use of electronic textbooks (e-book) has been heavily studied over the years due to their flexibility, accessibility, interactivity and extensibility. Yet current shortcomings of e-book, which is often just a digitized version of the…

Digital Libraries · Computer Science 2018-01-23 Noel Nuo Wi Tay , Sheng-Chi Yang , Chang-Shing Lee , Naoyuki Kubota

In recent years, AI models that mine intrinsic patterns from molecular structures and protein sequences have shown promise in accelerating drug discovery. However, these methods partly lag behind real-world pharmaceutical approaches of…

Machine Learning · Computer Science 2023-10-17 Yizhen Luo , Xing Yi Liu , Kai Yang , Kui Huang , Massimo Hong , Jiahuan Zhang , Yushuai Wu , Zaiqing Nie