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Statistical analysis of magnetic resonance imaging (MRI) can help radiologists to detect pathologies that are otherwise likely to be missed. Deep learning (DL) has shown promise in modeling complex spatial data for brain anomaly detection.…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 Victor Saase , Holger Wenz , Thomas Ganslandt , Christoph Groden , Máté E. Maros

Parkinson's Disease (PD) is a devastating neurodegenerative disorder that affects millions of people around the globe. Many researchers are continuously working to understand PD and develop treatments to improve the condition of PD…

Applications · Statistics 2025-12-16 Malinda Iluppangama , Dilmi Abeywardana , Chris Tsokos

Epilepsy significantly impacts global health, affecting about 65 million people worldwide, along with various animal species. The diagnostic processes of epilepsy are often hindered by the transient and unpredictable nature of seizures.…

Signal Processing · Electrical Eng. & Systems 2026-04-21 Z. Wang , S. Li , Dongrui Wu

Objective: Post-traumatic epilepsy (PTE) is a debilitating neurological disorder that develops after traumatic brain injury (TBI). Early prediction of PTE remains challenging due to heterogeneous clinical data, limited positive cases, and…

Machine Learning · Computer Science 2026-04-17 Wenhui Cui , Nicholas Swingle , Anand A. Joshi , Dileep Nair , Richard M. Leahy

During clinical treatment for epilepsy, the area of the brain thought to be responsible for pathological activity is identified. This identification is typically performed through visual assessment of EEG recordings; however, this is time…

Over the past few decades, electroencephalography (EEG) monitoring has become a pivotal tool for diagnosing neurological disorders, particularly for detecting seizures. Epilepsy, one of the most prevalent neurological diseases worldwide,…

Machine Learning · Computer Science 2025-08-08 Andrea Pollastro , Francesco Isgrò , Roberto Prevete

Proton pencil beam scanning (PBS) treatment planning for head and neck (H&N) cancers is a time-consuming and experience-demanding task where a large number of planning objectives are involved. Deep reinforcement learning (DRL) has recently…

Quantitative Methods · Quantitative Biology 2024-09-19 Qingqing Wang , Chang Chang

Epilepsy is one of the common neurological disorders characterized by recurrent and uncontrollable seizures, which seriously affect the life of patients. In many cases, electroencephalograms signal can provide important physiological…

Neurons and Cognition · Quantitative Biology 2023-08-15 Mohammad Reza Yousefi , Saina Golnejad , Melika Mohammad Hosseini , Amin Dehghani

In this work, we explore the various Brain Neuron tracking techniques, which is one of the most significant applications of Diffusion Tensor Imaging. Tractography provides us with a non-invasive method to analyze underlying tissue…

Computer Vision and Pattern Recognition · Computer Science 2018-06-12 Nandakishore Puttashamachar , Ulas Bagci

Hippocampus segmentation on magnetic resonance imaging is of key importance for the diagnosis, treatment decision and investigation of neuropsychiatric disorders. Automatic segmentation is an active research field, with many recent models…

Image and Video Processing · Electrical Eng. & Systems 2021-02-12 Diedre Carmo , Bruna Silva , Clarissa Yasuda , Letícia Rittner , Roberto Lotufo

Deep Brain Stimulation (DBS) is effective in treating neurological disorders but involves invasive surgery. Non-invasive DBS aims to overcome surgical risks by means of externally applied electromagnetic fields. In this work, we present a…

Medical Physics · Physics 2026-02-24 Mika Söderström , Melker Carlsson , Patrik Nicolausson , Mariana Dalarsson

Guideline-based treatment for sepsis and septic shock is difficult because sepsis is a disparate range of life-threatening organ dysfunctions whose pathophysiology is not fully understood. Early intervention in sepsis is crucial for patient…

Machine Learning · Computer Science 2021-09-24 Ran Liu , Joseph L. Greenstein , James C. Fackler , Jules Bergmann , Melania M. Bembea , Raimond L. Winslow

Recently, neural architecture search (NAS) has been applied to automatically search high-performance networks for medical image segmentation. The NAS search space usually contains a network topology level (controlling connections among…

Computer Vision and Pattern Recognition · Computer Science 2021-03-31 Yufan He , Dong Yang , Holger Roth , Can Zhao , Daguang Xu

Brain stroke has become a significant burden on global health and thus we need remedies and prevention strategies to overcome this challenge. For this, the immediate identification of stroke and risk stratification is the primary task for…

Image and Video Processing · Electrical Eng. & Systems 2025-01-07 Prantik Deb , Lalith Bharadwaj Baru , Kamalaker Dadi , Bapi Raju S

Advancements in neurosurgical robotics have improved medical procedures, particularly deep brain stimulation, where robots combine human and machine intelligence to precisely implant electrodes in the brain. While effective, this procedure…

Systems and Control · Electrical Eng. & Systems 2023-12-14 Mobina Zibandepour , Akram Shojaei , Arash Abbasi Larki , Mehdi Delrobaei

Epilepsy is a neurological disorder arising from anomalies of the electrical activity in the brain, affecting about 0.5--0.8\% of the world population. Several studies investigated the relationship between seizures and brainwave…

Machine Learning · Computer Science 2018-01-25 Paolo Detti , Garazi Zabalo Manrique de Lara , Renato Bruni , Marco Pranzo , Francesco Sarnari

While Deep Learning (DL) is often considered the state-of-the art for Artificial Intelligence-based medical decision support, it remains sparsely implemented in clinical practice and poorly trusted by clinicians due to insufficient…

Machine Learning · Computer Science 2020-12-23 Valentin Gabeff , Tomas Teijeiro , Marina Zapater , Leila Cammoun , Sylvain Rheims , Philippe Ryvlin , David Atienza

Accurate and timely detection of medical adverse events (AEs) from free-text medical narratives is challenging. Natural language processing (NLP) with deep learning has already shown great potential for analyzing free-text data, but its…

Computation and Language · Computer Science 2020-11-26 Alireza Borjali , Martin Magneli , David Shin , Henrik Malchau , Orhun K. Muratoglu , Kartik M. Varadarajan

Vagus Nerve Stimulation (VNS) is an established palliative treatment for drug resistant epilepsy. While effective for many patients, its mechanism of action is incompletely understood. Predicting individuals' response, or optimum…

Neurons and Cognition · Quantitative Biology 2024-06-06 John F. Ingham , Frances Hutchings , Paolo Zuliani , Yujiang Wang , Sadegh Soudjani , Peter N. Taylor

Sepsis is a potentially life threatening inflammatory response to infection or severe tissue damage. It has a highly variable clinical course, requiring constant monitoring of the patient's state to guide the management of intravenous…

Machine Learning · Computer Science 2022-02-21 Thesath Nanayakkara , Gilles Clermont , Christopher James Langmead , David Swigon