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Phase separation routinely occurs in both living and synthetic systems. These phases are often complex and distinguished by features including crystallinity, nematic order, and a host of other nonconserved order parameters. For systems at…

Statistical Mechanics · Physics 2025-12-08 Daniel Evans , Ahmad K. Omar

Multicomponent phase separation is a routine occurrence in both living and synthetic systems. Thermodynamics provides a straightforward path to determine the phase boundaries that characterize these transitions for systems at equilibrium.…

Statistical Mechanics · Physics 2025-12-08 Yu-Jen Chiu , Daniel Evans , Ahmad K. Omar

The discerning behavior of living systems relies on accurate interactions selected from the lot of molecular collisions occurring in the cell. To ensure the reliability of interactions, binding partners are classically envisioned as finely…

Molecular Networks · Quantitative Biology 2016-09-28 Denis Michel , Benjamin Boutin , Philippe Ruelle

Understanding the rules underlying organismal development is a major unsolved problem in biology. Each cell in a developing organism responds to signals in its local environment by dividing, excreting, consuming, or reorganizing, yet how…

Cell Behavior · Quantitative Biology 2025-08-20 Ramya Deshpande , Francesco Mottes , Ariana-Dalia Vlad , Michael P. Brenner , Alma dal Co

Overcoming robotics challenges in the real world requires resilient control systems capable of handling a multitude of environments and unforeseen events. Evolutionary optimization using simulations is a promising way to automatically…

Robotics · Computer Science 2019-04-12 Jørgen Nordmoen , Tønnes F. Nygaard , Kai Olav Ellefsen , Kyrre Glette

We consider a new class of interacting particle systems with a countable number of interacting components. The system represents the time evolution of the membrane potentials of an infinite set of interacting neurons. We prove the existence…

Methodology · Statistics 2016-03-23 Karina Y. Yaginuma

The ability to absorb mutations while retaining structure and function, or mutational robustness, is a remarkable property of natural proteins. In this Letter, we use a computational model of organismic evolution [Zeldovich et al, PLOS Comp…

Biomolecules · Quantitative Biology 2008-06-25 Konstantin B. Zeldovich , Eugene I. Shakhnovich

Motor proteins are active enzymatic molecules that drive a variety of biological processes, including transfer of genetic information, cellular transport, cell motility and muscles contraction. It is known that these biological molecular…

Soft Condensed Matter · Physics 2018-01-17 Luiza V. F. Gomes , Anatoly B. Kolomeisky

Motivated by a model of an area-wide integrated pest management, we develop an interacting particle system evolving in a random environment. It is a generalised contact process in which the birth rate takes two possible values, determined…

Probability · Mathematics 2015-08-27 Kevin Kuoch

Phase separation is the thermodynamic process that explains how droplets form in multicomponent fluids. These droplets can provide controlled compartments to localize chemical reactions, and reactions can also affect the droplets' dynamics.…

Soft Condensed Matter · Physics 2022-09-02 David Zwicker

Phase separation dynamics with an initially non-uniform concentration are studied. Critical and off-critical behavior is observed simultaneously. A mechanism for an expanding phase separated region is demonstrated and the time dependence of…

Condensed Matter · Physics 2009-10-22 A. M. Lacasta , J. M. Sancho , Chuck Yeung

We numerically investigate the competition between phase separation and dynamical arrest in a colloidal system interacting via a short ranged attractive potential. Equilibrium fluid configurations are quenched at two different temperatures…

Soft Condensed Matter · Physics 2007-05-23 G. Foffi , C. De Michele , F. Sciortino , P. Tartaglia

The effect of interactions on dynamics of coupled motor proteins is investigated theoretically. A simple stochastic discrete model, that allows to calculate explicitly the dynamic properties of the system, is developed. It is shown that…

Soft Condensed Matter · Physics 2009-11-11 Evgeny B. Stukalin , Anatoly B. Kolomeisky

A new method is introduced for analysis of interactions between time-dependent coupled oscillators, based on the signals they generate. It distinguishes unsynchronized dynamics from noise-induced phase slips, and enables the evolution of…

Data Analysis, Statistics and Probability · Physics 2012-08-09 Tomislav Stankovski , Andrea Duggento , Peter V. E. McClintock , Aneta Stefanovska

This paper demonstrates that simple yet important characteristics of coevolution can occur in evolutionary algorithms when only a few conditions are met. We find that interaction-based fitness measurements such as fitness (linear) ranking…

Neural and Evolutionary Computing · Computer Science 2009-07-03 James M Whitacre

Ecological communities with many species can be classified into dynamical phases. In systems with all-to-all interactions, a phase where a fixed point is always reached and a dynamically-fluctuating phase have been found. The dynamics when…

Populations and Evolution · Quantitative Biology 2023-08-04 Stav Marcus , Ari M Turner , Guy Bunin

Complex systems are often characterized by the interplay of multiple interconnected dynamical processes operating across a range of temporal scales. This phenomenon is widespread in both biological and artificial scenarios, making it…

Statistical Mechanics · Physics 2025-09-08 Giorgio Nicoletti , Daniel M. Busiello

Interacting proteins coevolve at multiple but interconnected scales, from the residue-residue over the protein-protein up to the family-family level. The recent accumulation of enormous amounts of sequence data allows for the development of…

Biomolecules · Quantitative Biology 2019-06-25 Hendrik Szurmant , Martin Weigt

The phase transition kinetics in three phase systems was investigated using the numerically efficient cell dynamics method. A phasefield model with a simple analytical free energy and single order parameter was used to study the kinetics…

Materials Science · Physics 2010-03-23 Masao Iwamatsu

Biological cells exhibit a hierarchical spatial organization, where various compartments harbor condensates that form by phase separation. Cells can control the emergence of these condensates by affecting compartment size, the amount of the…

Biological Physics · Physics 2025-04-03 Riccardo Rossetto , Gerrit Wellecke , David Zwicker