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Low-dose computed tomography (CT) denoising algorithms aim to enable reduced patient dose in routine CT acquisitions while maintaining high image quality. Recently, deep learning~(DL)-based methods were introduced, outperforming…

Image and Video Processing · Electrical Eng. & Systems 2022-10-21 Fabian Wagner , Mareike Thies , Felix Denzinger , Mingxuan Gu , Mayank Patwari , Stefan Ploner , Noah Maul , Laura Pfaff , Yixing Huang , Andreas Maier

Computed tomography (CT) is routinely used for three-dimensional non-invasive imaging. Numerous data-driven image denoising algorithms were proposed to restore image quality in low-dose acquisitions. However, considerably less research…

The use of deep learning has successfully solved several problems in the field of medical imaging. Deep learning has been applied to the CT denoising problem successfully. However, the use of deep learning requires large amounts of data to…

Image and Video Processing · Electrical Eng. & Systems 2022-04-04 Mayank Patwari , Ralf Gutjahr , Rainer Raupach , Andreas Maier

Denoising of clinical CT images is an active area for deep learning research. Current clinically approved methods use iterative reconstruction methods to reduce the noise in CT images. Iterative reconstruction techniques require multiple…

Image and Video Processing · Electrical Eng. & Systems 2020-07-10 Mayank Patwari , Ralf Gutjahr , Rainer Raupach , Andreas Maier

With the development of deep learning, medical image processing has been widely used to assist clinical research. This paper focuses on the denoising problem of low-dose computed tomography using deep learning. Although low-dose computed…

Image and Video Processing · Electrical Eng. & Systems 2026-05-19 Zhilin Guan , Wei Zhang

Long lasting efforts have been made to reduce radiation dose and thus the potential radiation risk to the patient for computed tomography acquisitions without severe deterioration of image quality. To this end, numerous reconstruction and…

Medical Physics · Physics 2024-10-07 Elias Eulig , Björn Ommer , Marc Kachelrieß

Denoising low-dose computed tomography (CT) images is a critical task in medical image computing. Supervised deep learning-based approaches have made significant advancements in this area in recent years. However, these methods typically…

Image and Video Processing · Electrical Eng. & Systems 2023-07-17 Xuan Liu , Yaoqin Xie , Jun Cheng , Songhui Diao , Shan Tan , Xiaokun Liang

Despite the indispensable role of X-ray computed tomography (CT) in diagnostic medicine field, the associated ionizing radiation is still a major concern considering that it may cause genetic and cancerous diseases. Decreasing the exposure…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Ti Bai , Dan Nguyen , Biling Wang , Steve Jiang

Computed tomography (CT) has been used worldwide as a non-invasive test to assist in diagnosis. However, the ionizing nature of X-ray exposure raises concerns about potential health risks such as cancer. The desire for lower radiation doses…

Image and Video Processing · Electrical Eng. & Systems 2024-07-01 Yucheng Lu , Zhixin Xu , Moon Hyung Choi , Jimin Kim , Seung-Won Jung

Noise in low-dose computed tomography (LDCT) can obscure important diagnostic details. While deep learning offers powerful denoising, supervised methods require impractical paired data, and self-supervised alternatives often use opaque,…

Image and Video Processing · Electrical Eng. & Systems 2026-02-19 Yipeng Sun , Linda-Sophie Schneider , Siyuan Mei , Jinhua Wang , Ge Hu , Mingxuan Gu , Chengze Ye , Fabian Wagner , Lan Song , Siming Bayer , Andreas Maier

Most of the Deep Neural Networks (DNNs) based CT image denoising literature shows that DNNs outperform traditional iterative methods in terms of metrics such as the RMSE, the PSNR and the SSIM. In many instances, using the same metrics, the…

Computer Vision and Pattern Recognition · Computer Science 2021-11-19 Prabhat KC , Rongping Zeng , M. Mehdi Farhangi , Kyle J. Myers

Computed tomography (CT) has played a vital role in medical diagnosis, assessment, and therapy planning, etc. In clinical practice, concerns about the increase of X-ray radiation exposure attract more and more attention. To lower the X-ray…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 Zhicheng Zhang , Xiaokun Liang , Wei Zhao , Lei Xing

Deep learning based solutions are being succesfully implemented for a wide variety of applications. Most notably, clinical use-cases have gained an increased interest and have been the main driver behind some of the cutting-edge data-driven…

Image and Video Processing · Electrical Eng. & Systems 2023-04-04 Theodor Cheslerean-Boghiu , Felix C. Hofmann , Manuel Schultheiß , Franz Pfeiffer , Daniela Pfeiffer , Tobias Lasser

Low-dose CT images are essential for reducing radiation exposure in cancer screening, pediatric imaging, and longitudinal monitoring protocols, but their quality is often degraded by noise from low-dose acquisition, patient motion, or…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Jitindra Fartiyal , Pedro Freire , Sergei K. Turitsyn , Sergei G. Solovski

Image denoising techniques are essential to reducing noise levels and enhancing diagnosis reliability in low-dose computed tomography (CT). Machine learning based denoising methods have shown great potential in removing the complex and…

Computer Vision and Pattern Recognition · Computer Science 2017-08-29 Dufan Wu , Kyungsang Kim , Georges El Fakhri , Quanzheng Li

The resurgence of deep neural networks has created an alternative pathway for low-dose computed tomography denoising by learning a nonlinear transformation function between low-dose CT (LDCT) and normal-dose CT (NDCT) image pairs. However,…

Image and Video Processing · Electrical Eng. & Systems 2022-11-04 Sutanu Bera , Prabir Kumar Biswas

The current deep learning approaches for low-dose CT denoising can be divided into paired and unpaired methods. The former involves the use of well-paired datasets, whilst the latter relaxes this constraint. The large availability of…

Image and Video Processing · Electrical Eng. & Systems 2023-04-12 Francesco Di Feola , Lorenzo Tronchin , Paolo Soda

Low-dose CT denoising is a challenging task that has been studied by many researchers. Some studies have used deep neural networks to improve the quality of low-dose CT images and achieved fruitful results. In this paper, we propose a deep…

Image and Video Processing · Electrical Eng. & Systems 2019-02-28 Maryam Gholizadeh-Ansari , Javad Alirezaie , Paul Babyn

Low dose computed tomography (LDCT) is desirable for both diagnostic imaging and image guided interventions. Denoisers are openly used to improve the quality of LDCT. Deep learning (DL)-based denoisers have shown state-of-the-art…

Image and Video Processing · Electrical Eng. & Systems 2020-12-08 Ti Bai , Biling Wang , Dan Nguyen , Bao Wang , Bin Dong , Wenxiang Cong , Mannudeep K. Kalra , Steve Jiang

Commercial iterative reconstruction techniques on modern CT scanners target radiation dose reduction but there are lingering concerns over their impact on image appearance and low contrast detectability. Recently, machine learning,…

Computer Vision and Pattern Recognition · Computer Science 2019-07-16 Hongming Shan , Atul Padole , Fatemeh Homayounieh , Uwe Kruger , Ruhani Doda Khera , Chayanin Nitiwarangkul , Mannudeep K. Kalra , Ge Wang
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