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A single biomedical image can be meaningfully segmented in multiple ways, depending on the desired application. For instance, a brain MRI can be segmented according to tissue types, vascular territories, broad anatomical regions,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Marianne Rakic , Siyu Gai , Etienne Chollet , John V. Guttag , Adrian V. Dalca

Drawing and visualisation of molecular structures are some of the most common tasks carried out in structural glycobiology, typically using various software. In this perspective article, we outline developments in the computational tools…

Quantitative Methods · Quantitative Biology 2020-10-07 Kanhaya Lal , Rafael Bermeo , Serge Pérez

Brains with complex distortion of cerebral anatomy present several challenges to automatic tissue segmentation methods of T1-weighted MR images. First, the very high variability in the morphology of the tissues can be incompatible with the…

Tissues and Organs · Quantitative Biology 2020-03-25 Gabriele Amorosino , Denis Peruzzo , Pietro Astolfi , Daniela Redaelli , Paolo Avesani , Filippo Arrigoni , Emanuele Olivetti

A recent interest in resting state functional magnetic resonance imaging (rsfMRI) lies in subdividing the human brain into anatomically and functionally distinct regions of interest. For example, brain parcellation is often used for…

Scientists often explore and analyze large-scale scientific simulation data by leveraging two- and three-dimensional visualizations. The data and tasks can be complex and therefore best supported using myriad display technologies, from…

Human-Computer Interaction · Computer Science 2024-04-30 Thomas Marrinan , Madeleine Moeller , Alina Kanayinkal , Victor A. Mateevitsi , Michael E. Papka

Analysis of genomics data is central to nearly all areas of modern biology. Despite significant progress in artificial intelligence (AI) and computational methods, these technologies require significant human oversight to generate novel and…

Deep neural networks are a family of computational models that have led to a dramatical improvement of the state of the art in several domains such as image, voice or text analysis. These methods provide a framework to model complex,…

Machine Learning · Statistics 2018-02-12 Louis Falissard , Guy Fagherazzi , Newton Howard , Bruno Falissard

Visualisation facilitates the understanding of scientific data both through exploration and explanation of visualised data. Provenance contributes to the understanding of data by containing the contributing factors behind a result. With the…

Databases · Computer Science 2015-02-06 Bilal Arshad , Kamran Munir , Richard McClatchey , Saad Liaquat

Brain tumor segmentation is a fundamental step in assessing a patient's cancer progression. However, manual segmentation demands significant expert time to identify tumors in 3D multimodal brain MRI scans accurately. This reliance on manual…

Image and Video Processing · Electrical Eng. & Systems 2024-05-07 Fadillah Maani , Anees Ur Rehman Hashmi , Numan Saeed , Mohammad Yaqub

Neuropathological analyses benefit from spatially precise volumetric reconstructions that enhance anatomical delineation and improve morphometric accuracy. Our prior work has shown the feasibility of reconstructing 3D brain volumes from 2D…

Advances in data collection in radiation therapy have led to an abundance of opportunities for applying data mining and machine learning techniques to promote new data-driven insights. In light of these advances, supporting collaboration…

Human-Computer Interaction · Computer Science 2020-10-22 Andrew Wentzel , Guadalupe Canahuate , Lisanne van Dijk , Abdallah Mohamed , Clifton David Fuller , G. Elisabeta Marai

The R programming language is built on an ecosystem of packages, some that allow analysts to accomplish the same tasks. For example, there are at least two clear workflows for creating data visualizations in R: using the base graphics…

Other Statistics · Statistics 2019-03-06 Leslie Myint , Aboozar Hadavand , Leah Jager , Jeffrey Leek

In this work, we utilize image segmentation to visually identify blood vessels in retinal examination images. This process is typically carried out manually. However, we can employ heuristic methods and machine learning to automate or at…

Image and Video Processing · Electrical Eng. & Systems 2023-09-01 João Henrique Pereira Machado , Gilson Adamczuk Oliveira , Érick Oliveira Rodrigues

It is shown how to set up, conduct, and analyze large simulation studies with the new R package simsalapar = simulations simplified and launched parallel. A simulation study typically starts with determining a collection of input variables…

Computation · Statistics 2013-09-18 Marius Hofert , Martin Mächler

Physical models in the form of partial differential equations serve as important priors for many under-constrained problems. One such application is tumor treatment planning, which relies on accurately estimating the spatial distribution of…

We present a light and fast, public available, ray-tracer {\tt Splotch} software tool which supports the effective visualization of cosmological simulations data. We describe the algorithm it relies on, which is designed in order to deal…

Astrophysics · Physics 2008-12-18 K. Dolag , M. Reinecke , C. Gheller , S. Imboden

Brain MR image segmentation is a key task in neuroimaging studies. It is commonly conducted using standard computational tools, such as FSL, SPM, multi-atlas segmentation etc, which are often registration-based and suffer from expensive…

Image and Video Processing · Electrical Eng. & Systems 2019-08-29 Chengliang Dai , Yuanhan Mo , Elsa Angelini , Yike Guo , Wenjia Bai

Computational neuroimaging involves analyzing brain images or signals to provide mechanistic insights and predictive tools for human cognition and behavior. While diffusion models have shown stability and high-quality generation in natural…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Haokai Zhao , Haowei Lou , Lina Yao , Wei Peng , Ehsan Adeli , Kilian M Pohl , Yu Zhang

Fully immersive virtual reality (VR) has the potential to improve neurosurgical planning. For example, it may offer 3D visualizations of relevant anatomical structures with complex shapes, such as blood vessels and tumors. However, there is…

Human-Computer Interaction · Computer Science 2019-08-15 Lukas D. J. Fiederer , Hisham Alwanni , Martin Völker , Oliver Schnell , Jürgen Beck , Tonio Ball

We propose a visualization application, designed for the exploration of human spine simulation data. Our goal is to support research in biomechanical spine simulation and advance efforts to implement simulation-backed analysis in surgical…

Graphics · Computer Science 2021-02-02 Pepe Eulzer , Sabine Bauer , Francis Kilian , Kai Lawonn