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Publicly available collections of drug-like molecules have grown to comprise 10s of billions of possibilities in recent history due to advances in chemical synthesis. Traditional methods for identifying "hit" molecules from a large…

On-device learning has emerged as a prevailing trend that avoids the slow response time and costly communication of cloud-based learning. The ability to learn continuously and indefinitely in a changing environment, and with resource…

Machine Learning · Computer Science 2024-03-08 Xiaofan Yu , Anthony Thomas , Ivannia Gomez Moreno , Louis Gutierrez , Tajana Rosing

The curse of dimensionality presents a pervasive challenge in optimization problems, with exponential expansion of the search space rapidly causing traditional algorithms to become inefficient or infeasible. An adaptive sampling strategy is…

Numerical Analysis · Mathematics 2025-11-18 Julian Soltes

Epilepsy is a common disease of the nervous system. Timely prediction of seizures and intervention treatment can significantly reduce the accidental injury of patients and protect the life and health of patients. This paper presents a…

Signal Processing · Electrical Eng. & Systems 2024-10-01 Qinyu Chen , Congyi Sun , Chang Gao , Shih-Chii Liu

Electroencephalography (EEG) analysis extracts critical information from brain signals, which has provided fundamental support for various applications, including brain-disease diagnosis and brain-computer interface. However, the real-time…

Signal Processing · Electrical Eng. & Systems 2023-01-25 Tao Yan , Maoqi Zhang , Sen Wan , Kaifeng Shang , Haiou Zhang , Xun Cao , Xing Lin , Qionghai Dai

Epilepsy is a neurological disorder classified as the second most serious neurological disease known to humanity, after stroke. Localization of the epileptogenic zone is an important step for epileptic patient treatment, which starts with…

The two-point central difference is a common algorithm in biological signal processing and is particularly useful in analyzing physiological signals. In this paper, we develop a model-based classification method to detect epileptic seizures…

Applications · Statistics 2020-06-01 Antonio Quintero-Rincon , Carlos D'Giano , Hadj Batatia

In this study, we developed and tested machine learning models to predict epilepsy surgical outcome using noninvasive clinical and demographic data from patients. Methods: Seven dif-ferent categorization algorithms were used to analyze the…

In current clinical practice, electroencephalograms (EEG) are reviewed and analyzed by well-trained neurologists to provide supports for therapeutic decisions. The way of manual reviewing is labor-intensive and error prone. Automatic and…

Signal Processing · Electrical Eng. & Systems 2019-06-07 Xinghua Yao , Qiang Cheng , Guo-Qiang Zhang

Machine Learning algorithms based on Brain-inspired Hyperdimensional(HD) computing imitate cognition by exploiting statistical properties of high-dimensional vector spaces. It is a promising solution for achieving high energy efficiency in…

Machine Learning · Computer Science 2022-10-12 Samuel Bosch , Alexander Sanchez de la Cerda , Mohsen Imani , Tajana Simunic Rosing , Giovanni De Micheli

Hyperdimensional Computing (HDC) has obtained abundant attention as an emerging non von Neumann computing paradigm. Inspired by the way human brain functions, HDC leverages high dimensional patterns to perform learning tasks. Compared to…

Neural and Evolutionary Computing · Computer Science 2022-07-27 Dongning Ma , Xun Jiao

In clinical practice, electroencephalography (EEG) plays an important role in the diagnosis of epilepsy. EEG-based computer-aided diagnosis of epilepsy can greatly improve the ac-curacy of epilepsy detection while reducing the workload of…

Signal Processing · Electrical Eng. & Systems 2026-03-24 Andong Li , Zhaohong Deng , Qiongdan Lou

Hyperdimensional computing (HDC) is a method to perform classification that uses binary vectors with high dimensions and the majority rule. This approach has the potential to be energy-efficient and hence deemed suitable for…

Machine Learning · Computer Science 2023-10-13 Zhanglu Yan , Shida Wang , Kaiwen Tang , Weng-Fai Wong

Reliable seizure detection is critical for diagnosing and managing epilepsy, yet clinical workflows remain dependent on time-consuming manual EEG interpretation. While machine learning has shown promise, existing approaches often rely on…

Machine Learning · Computer Science 2025-08-12 Bartlomiej Chybowski , Shima Abdullateef , Hollan Haule , Alfredo Gonzalez-Sulser , Javier Escudero

Early management and better clinical outcomes for epileptic patients depend on seizure prediction. The accuracy and false alarm rates of existing systems are often compromised by their dependence on static thresholds and basic…

Signal Processing · Electrical Eng. & Systems 2025-01-29 Mathan Kumar Mounagurusamy , Thiyagarajan V S , Abdur Rahman , Shravan Chandak , D. Balaji , Venkateswara Rao Jallepalli

Epilepsy is a chronic neurological condition characterized by recurrent seizures, with global prevalence estimated at 50 million people worldwide. While progress in high-throughput sequencing has allowed for broad-based transcriptomic…

Genomics · Quantitative Biology 2025-10-02 Muhammad Omer Latif , Hayat Ullah , Muhammad Ali Shafique , Zhihua Dong

Alcohol consumption has a significant impact on individuals' health, with even more pronounced consequences when consumption becomes excessive. One approach to promoting healthier drinking habits is implementing just-in-time interventions,…

Since the manual detection of electrographic seizures in continuous electroencephalogram (EEG) monitoring is very time-consuming and requires a trained expert, attempts to develop automatic seizure detection are diverse and ongoing. Machine…

Signal Processing · Electrical Eng. & Systems 2019-08-02 Poomipat Boonyakitanont , Apiwat Lek-uthai , Krisnachai Chomtho , Jitkomut Songsiri

Epileptic seizure detection from EEG signals remains challenging due to the high dimensionality and nonlinear, potentially stochastic, dynamics of neural activity. In this work, we investigate whether features derived from topological data…

Machine Learning · Computer Science 2026-04-15 Sunia Tanweer , Narayan Puthanmadam Subramaniyam , Firas A. Khasawneh

Since last 2 decades, High Frequency Oscillations (HFOs) are studied as a promising biomarker to localize the epileptogenic zone of patients with refractory focal epilepsy. As HFOs visual detection is time consuming and subjective,…

Signal Processing · Electrical Eng. & Systems 2023-01-23 Gaëlle Milon-Harnois , Nisrine Jrad , Daniel Schang , Patrick van Bogaert , Pierre Chauvet
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