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High-density microfluidics is becoming an important experimental platform for studying complex biological systems such as synthetic gene regulatory networks, molecular biocomputating of engineered cells, distributing rapid point-of-care…

Biological Physics · Physics 2021-07-21 Sankar Raju Narayanasamy , Ramakrishna Vasireddi , Hoi-Ying Holman

Small volume fluid handling in single and multiphase microfluidics provides a promising strategy for efficient bio-chemical assays, low-cost point-of-care diagnostics and new approaches to scientific discoveries. However multiple barriers…

Instrumentation and Detectors · Physics 2015-06-22 George Korir , Manu Prakash

We present a microfluidic device that enables trapping, analysis, and on-demand release of individual microparticles through membrane deformation driven by pneumatic actuation. Inspired by Pachinko-style architectures, the system features…

Applied Physics · Physics 2025-07-10 Alexandre Chargueraud , Lars Kool , Jacques Fattaccioli

Microfluidic valves play a key role within microfluidic systems by regulating fluid flow through distinct microchannels, enabling many advanced applications in medical diagnostics, lab-on-chips, and laboratory automation. While microfluidic…

Materials Science · Physics 2023-12-19 Tinku Supakar , David Space , Sophy Meija , Rou Yu Tan , Jeffrey R. Alston , Eric A. Josephs

We propose a synthesis method for the design of digital twins applicable to various systems (pneumatic, hydraulic, electrical/electronic circuits). The methodology allows representing the operation of these systems through an active digital…

Systems and Control · Electrical Eng. & Systems 2024-10-01 Veyis Gunes

The vision of creating entirely-soft robots capable of performing complex tasks will be accomplished only when the controllers required for autonomous operation can be fully implemented on soft components. Despite recent advances in…

Robotics · Computer Science 2020-03-10 Ke Xu , Nestor O. Perez-Arancibia

Encapsulation of chemicals using polymer membranes enables to control their transport and delivery for applications such as agrochemistry or detergency. To rationalize the design of polymer capsules, it is necessary to understand how the…

Soft Condensed Matter · Physics 2018-12-18 Corentin Tregouët , Thomas Salez , Mathilde Reyssat , Cécile Monteux

Microfluidics involves the manipulation of flows at the microscale, typically requiring external power sources to generate pressure gradients. Alternatively, harnessing flows from active fluids, which are usually chaotic, has been proposed…

Microfluidics, the study of fluids in microscopic channels, has led to important advances in fields as diverse as microelectronics, biotechnology and chemistry. Microfluidic research is primarily based on the use of microfluidic chips,…

Systems and Control · Electrical Eng. & Systems 2024-07-15 Jorge Vicente Martinez , Edgar Ramirez-Laboreo , Pablo Calderon Gil

The miniaturization and integration of electronic circuitry has not only made the enormous increase in performance of semiconductor devices possible but also spawned a myriad of new products and applications ranging from a cellular phone to…

Fluid Dynamics · Physics 2011-03-16 A. Rathgeber , C. Strobl , H. -J. Kutschera , A. Wixforth

Microfluidic chips provide unparalleled control over droplets and jets, which have advanced all natural sciences. However, microfluidic applications could be vastly expanded by increasing the per-channel throughput and directly exploiting…

The integration of a PDMS membrane within orthogonally placed PMMA microfluidic channels enables the pneumatic actuation of valves within bonded PMMA-PDMS-PMMA multilayer devices. Here, surface functionalization of PMMA substrates via acid…

Other Computer Science · Computer Science 2008-12-18 A. G. G. Toh , Z. F. Wang , S. H. Ng

We implement a computational periporomechanics model for simulating localized failure in unsaturated porous media. The coupled periporomechanics model is based on the peridynamic state concept and the effective force state concept. The…

Numerical Analysis · Mathematics 2021-07-07 Shashank Menon , Xiaoyu Song

In this paper, we present a modular pressure control system called PneuDrive that can be used for large-scale, pneumatically-actuated soft robots. The design is particularly suited for situations which require distributed pressure control…

Robotics · Computer Science 2025-04-02 Curtis C. Johnson , Daniel G. Cheney , Dallin L. Cordon , Marc D. Killpack

We propose a neural physics system for real-time, interactive fluid simulations. Traditional physics-based methods, while accurate, are computationally intensive and suffer from latency issues. Recent machine-learning methods reduce…

Machine Learning · Computer Science 2025-05-27 Jingxuan Xu , Hong Huang , Chuhang Zou , Manolis Savva , Yunchao Wei , Wuyang Chen

Inexpensive, portable lab-on-a-chip devices would revolutionize fields like environmental monitoring and global health, but current microfluidic chips are tethered to extensive off-chip hardware. Insects, however, are self-contained and…

Arrays of H-shape microfluidic channels connecting two different fluidic reservoirs have been built with silicon/SU8 microfabrication technologies utilized in production of thermal inkjet printheads. The fluids are delivered to the channels…

Fluid Dynamics · Physics 2018-02-13 Brandon S. Hayes , Alexander N. Govyadinov , Pavel E. Kornilovitch

To facilitate the use and portability of Lab on a chip technology, it is desirable to avoid the use of bulky electronic systems for flow control. Developed self-powered microsystems typically move only small volumes of fluid performing up…

Acoustic manipulation in microfluidic devices enables contactless handling of biological cells for Lab-on-Chip applications. This paper analyzes the controllability of multi-particle systems in a one-dimensional acoustic standing wave…

Systems and Control · Electrical Eng. & Systems 2025-04-07 Dongjun Wu , Guilherme Perticarari , Thierry Baasch

Microfluidics and lab-on-a-chip technologies have made it possible to manipulate small volume liquids with unprecedented resolution, automation and integration. However, most current microfluidic systems still rely on bulky off-chip…

Instrumentation and Detectors · Physics 2014-05-22 Baichen Li , Lin Li , Allan Guan , Quan Dong , Kangcheng Ruan , Ronggui Hu , Zhenyu Li
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