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With the advent of structured data in the form of social networks, genetic circuits and protein interaction networks, statistical analysis of networks has gained popularity over recent years. Stochastic block model constitutes a classical…

Statistics Theory · Mathematics 2015-05-27 Debdeep Pati , Anirban Bhattacharya

This study aims to estimate the parameters of a stochastic exposed-infected epidemiological model for the transmission dynamics of notifiable infectious diseases, based on observations related to isolated cases counts only. We use the…

Applications · Statistics 2024-04-15 Ibrahim Bouzalmat , Benoîte de Saporta , Solym M. Manou-Abi

In this paper, we outline the theory of epidemic percolation networks and their use in the analysis of stochastic SIR epidemic models on undirected contact networks. We then show how the same theory can be used to analyze stochastic SIR…

Quantitative Methods · Quantitative Biology 2023-10-24 Eben Kenah , James M. Robins

Computational models for the simulation of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic evolution would be extremely useful to support authorities in designing healthcare policies and lockdown measures to…

Populations and Evolution · Quantitative Biology 2020-04-20 Marco Paggi

With the unfolding of the COVID-19 pandemic, mathematical modeling of epidemics has been perceived and used as a central element in understanding, predicting, and governing the pandemic event. However, soon it became clear that long term…

Populations and Evolution · Quantitative Biology 2020-07-09 Ziqi Wang , Marco Broccardo , Arnaud Mignan , Didier Sornette

Dynamic models - often deterministic in nature - were used to estimate the basic reproductive number, R_0, of the 2014-5 Ebola virus disease (EVD) epidemic outbreak in West Africa. Estimates of R_0 were then used to project the likelihood…

Populations and Evolution · Quantitative Biology 2016-01-27 Bradford P Taylor , Jonathan Dushoff , Joshua S Weitz

We study sequential Bayesian inference in stochastic kinetic models with latent factors. Assuming continuous observation of all the reactions, our focus is on joint inference of the unknown reaction rates and the dynamic latent states,…

Computation · Statistics 2014-09-10 Junjing Lin , Michael Ludkovski

Stochasticity and spatial heterogeneity are of great interest recently in studying the spread of an infectious disease. The presented method solves an inverse problem to discover the effectively decisive topology of a heterogeneous network…

Artificial Intelligence · Computer Science 2015-03-13 Yoshiharu Maeno

Individual-based models of contagious processes are useful for predicting epidemic trajectories and informing intervention strategies. In such models, the incorporation of contact network information can capture the non-randomness and…

Populations and Evolution · Quantitative Biology 2023-11-09 Maxwell H. Wang , Jukka-Pekka Onnela

We extend the classical Susceptible-Infected-Recovered (SIR) model to a network-based framework where the degree distribution of nodes follows a Poisson distribution. This extension incorporates an additional parameter representing the mean…

Populations and Evolution · Quantitative Biology 2025-01-03 Josephine K. Wairimu , Andrew Gothard , Grzegorz A. Rempala

Recent pandemics have highlighted the critical role of infectious disease models in guiding public health decision-making, driving demand for realistic models that can provide timely answers under uncertainty. Compartmental models are…

Methodology · Statistics 2026-03-18 Xiahui Li , Fergus J. Chadwick , Ben Swallow

Moment-closure techniques are commonly used to generate low-dimensional deterministic models to approximate the average dynamics of stochastic systems on networks. The quality of such closures is usually difficult to asses and the…

Populations and Evolution · Quantitative Biology 2015-05-14 Lorenzo Pellis , Thomas House , Matt J. Keeling

This paper proposes a sequential ensemble methodology for epidemic modeling that integrates discrete-time Hawkes processes (DTHP) and Susceptible-Exposed-Infectious-Removed (SEIR) models. Motivated by the need for accurate and reliable…

Applications · Statistics 2026-01-21 Dhorasso Temfack , Jason Wyse

The ability to actually implement epidemic models is a crucial stake for public institutions, as they may be overtaken by the increasing complexity of current models and sometimes tend to revert to less elaborate models such as the SIR. In…

Physics and Society · Physics 2023-12-19 Louis Bremaud , Olivier Giraud , Denis Ullmo

In this project, identifiability, observability and uncertainty properties of the deterministic and Chain Binomial stochastic SIR, SEIR and SEIAR epidemiological models are studied. Techniques for modeling overdispersion are investigated…

Applications · Statistics 2024-05-29 Jonas Hjulstad

The expectation maximization (EM) algorithm is a widespread method for empirical Bayesian inference, but its expectation step (E-step) is often intractable. Employing a stochastic approximation scheme with Markov chain Monte Carlo (MCMC)…

Computation · Statistics 2024-02-29 Samuel Gruffaz , Kyurae Kim , Alain Oliviero Durmus , Jacob R. Gardner

We study the SIRS (Susceptible-Infected-Recovered-Susceptible) spreading processes over complex networks, by considering its exact $3^n$-state Markov chain model. The Markov chain model exhibits an interesting connection with its $2n$-state…

Social and Information Networks · Computer Science 2016-03-17 Navid Azizan Ruhi , Babak Hassibi

Accurate and reliable forecasting of epidemic incidences is critical for public health preparedness, yet it remains a challenging task due to complex nonlinear temporal dependencies and heterogeneous spatial interactions. Often, point…

Machine Learning · Statistics 2026-03-10 Rajdeep Pathak , Tanujit Chakraborty

We consider the case of performing Bayesian inference for stochastic epidemic compartment models, using incomplete time course data consisting of incidence counts that are either the number of new infections or removals in time intervals of…

Stochastic infectious disease models capture uncertainty in public health outcomes and have become increasingly popular in epidemiological practice. However, calibrating these models to observed data is challenging with existing methods for…

Methodology · Statistics 2024-12-18 Prayag Chatha , Fan Bu , Jeffrey Regier , Evan Snitkin , Jon Zelner