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Despite growing interest in using large language models (LLMs) in healthcare, current explorations do not assess the real-world utility and safety of LLMs in clinical settings. Our objective was to determine whether two LLMs can serve…

We know from prior work that LLMs encode social biases, and that this manifests in clinical tasks. In this work we adopt tools from mechanistic interpretability to unveil sociodemographic representations and biases within LLMs in the…

Computation and Language · Computer Science 2025-09-29 Hiba Ahsan , Arnab Sen Sharma , Silvio Amir , David Bau , Byron C. Wallace

Managing personal health data is a challenge in today's fragmented and institution-centric healthcare ecosystem. Individuals often lack meaningful control over their medical records, which are scattered across incompatible systems and…

Multimedia · Computer Science 2026-02-24 Sujaya Maiyya , Shantanu Sharma , Avinash Kumar

Large language models (LLMs) have been applied to tasks in healthcare, ranging from medical exam questions to responding to patient questions. With increasing institutional partnerships between companies producing LLMs and healthcare…

Computation and Language · Computer Science 2024-04-10 Jesutofunmi A. Omiye , Haiwen Gui , Shawheen J. Rezaei , James Zou , Roxana Daneshjou

Research is a tertiary priority in the EHR, where the priorities are patient care and billing. Because of this, the data is not standardized or formatted in a manner easily adapted to machine learning approaches. Data may be missing for a…

Machine Learning · Computer Science 2017-07-25 Brett K. Beaulieu-Jones

People increasingly rely on online sources for health information seeking due to their convenience and timeliness, traditionally using search engines like Google as the primary search agent. Recently, the emergence of generative Artificial…

Human-Computer Interaction · Computer Science 2024-03-18 Xin Sun , Rongjun Ma , Xiaochang Zhao , Zhuying Li , Janne Lindqvist , Abdallah El Ali , Jos A. Bosch

Electronic Health Records (EHRs) and routine documentation practices play a vital role in patients' daily care, providing a holistic record of health, diagnoses, and treatment. However, complex and verbose EHR narratives overload healthcare…

Computation and Language · Computer Science 2025-02-26 Yanjun Gao , Ruizhe Li , Emma Croxford , John Caskey , Brian W Patterson , Matthew Churpek , Timothy Miller , Dmitriy Dligach , Majid Afshar

The utilization of large language models (LLMs) in the Healthcare domain has generated both excitement and concern due to their ability to effectively respond to freetext queries with certain professional knowledge. This survey outlines the…

Computation and Language · Computer Science 2025-01-28 Kai He , Rui Mao , Qika Lin , Yucheng Ruan , Xiang Lan , Mengling Feng , Erik Cambria

Federated learning holds great potential for enabling large-scale healthcare research and collaboration across multiple centres while ensuring data privacy and security are not compromised. Although numerous recent studies suggest or…

Machine Learning · Computer Science 2025-02-05 Ming Li , Pengcheng Xu , Junjie Hu , Zeyu Tang , Guang Yang

Sensitive information is intrinsically tied to interactions in healthcare, and its protection is of paramount importance for achieving high-quality patient outcomes. Research in healthcare privacy and security is predominantly focused on…

Human-Computer Interaction · Computer Science 2023-06-27 Faiza Tazi , Archana Nandakumar , Josiah Dykstra , Prashanth Rajivan , Sanchari Das

Large language models (LLMs) are starting to complement traditional information seeking mechanisms such as web search. LLM-powered chatbots like ChatGPT are gaining prominence among the general public. AI chatbots are also increasingly…

Computation and Language · Computer Science 2025-11-25 Vibhor Agarwal , Yiqiao Jin , Mohit Chandra , Munmun De Choudhury , Srijan Kumar , Nishanth Sastry

Gastrointestinal (GI) tract cancers account for a substantial portion of the global cancer burden, where early diagnosis is critical for improved management and patient outcomes. The complex aetiologies and overlapping symptoms across GI…

Computation and Language · Computer Science 2025-03-19 Aniket Deroy , Subhankar Maity

Although large language models (LLMs) have been assessed for general medical knowledge using licensing exams, their ability to support clinical decision-making, such as selecting medical calculators, remains uncertain. We assessed nine…

Computation and Language · Computer Science 2025-03-25 Nicholas Wan , Qiao Jin , Joey Chan , Guangzhi Xiong , Serina Applebaum , Aidan Gilson , Reid McMurry , R. Andrew Taylor , Aidong Zhang , Qingyu Chen , Zhiyong Lu

Eating disorders (ED), a severe mental health condition with high rates of mortality and morbidity, affect millions of people globally, especially adolescents. The proliferation of online communities that promote and normalize ED has been…

Social and Information Networks · Computer Science 2024-05-24 Minh Duc Chu , Zihao He , Rebecca Dorn , Kristina Lerman

As Large Language Models (LLMs) become widely accessible, a detailed understanding of their knowledge within specific domains becomes necessary for successful real world use. This is particularly critical in the domains of medicine and…

Large language models (LLMs) have attracted significant attention for potential applications in digital health, while their application in mental health is subject to ongoing debate. This systematic review aims to evaluate the usage of LLMs…

Computers and Society · Computer Science 2024-08-14 Zhijun Guo , Alvina Lai , Johan Hilge Thygesen , Joseph Farrington , Thomas Keen , Kezhi Li

Using administrative patient-care data such as Electronic Health Records (EHR) and medical/ pharmaceutical claims for population-based scientific research has become increasingly common. With vast sample sizes leading to very small standard…

Methodology · Statistics 2023-08-21 Ritoban Kundu , Xu Shi , Jean Morrison , Jessica Barrett , Bhramar Mukherjee

This paper explores the development of the Six Stages of Information Search Model and its enhancement through the application of the Large Language Model (LLM) powered Information Search Processes (ISP) in healthcare. The Six Stages Model,…

Information Retrieval · Computer Science 2024-07-03 Forhan Bin Emdad , Mohammad Ishtiaque Rahman

Connected health is a multidisciplinary approach focused on health management, prioritizing pa-tient needs in the creation of tools, services, and treatments. This paradigm ensures proactive and efficient care by facilitating the timely…

Computers and Society · Computer Science 2025-10-13 Mira Raheem , Michael Papazoglou , Bernd Krämer , Neamat El-Tazi , Amal Elgammal

There is a clear need to involve patients in medical decisions. However, cognitive psychological research has highlighted the cognitive limitations of humans with respect to 1. Probabilistic assessment of the patient state and of potential…

Artificial Intelligence · Computer Science 2021-02-04 Yuval Shahar