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We review selected results related to robustness of networked systems in finite and asymptotically large size regimes, under static and dynamical settings. In the static setting, within the framework of flow over finite networks, we discuss…

Systems and Control · Electrical Eng. & Systems 2019-09-17 Ketan Savla , Jeff S. Shamma , Munther A. Dahleh

Deployment of neural networks on resource-constrained devices demands models that are both compact and robust to adversarial inputs. However, compression and adversarial robustness often conflict. In this work, we introduce a dynamical…

Machine Learning · Computer Science 2025-09-24 Steffen Schotthöfer , H. Lexie Yang , Stefan Schnake

Prevailing network control strategies, which rely on static shortest-path logic, suffer from catastrophic "stress concentration" on critical nodes. This paper introduces the System Relaxation Algorithm (SRA), a new control paradigm inspired…

Networking and Internet Architecture · Computer Science 2025-09-23 Zhiyuan Ren , Zhiliang Shuai , Wenchi Cheng

We analyze networked heterogeneous nonlinear systems, with diffusive coupling and interconnected over a generic static directed graph. Due to the network's hetereogeneity, complete synchronization is impossible, in general, but an emergent…

Optimization and Control · Mathematics 2022-06-01 Mohamed Maghenem , Elena Panteley , Antonio Loria

A convolutional neural network strongly robust to adversarial perturbations at reasonable computational and performance cost has not yet been demonstrated. The primate visual ventral stream seems to be robust to small perturbations in…

Machine Learning · Computer Science 2020-07-01 Manish V. Reddy , Andrzej Banburski , Nishka Pant , Tomaso Poggio

Reaction networks can display a wide array of dynamics. However, it is possible for different reaction networks to display the same dynamics. This phenomenon is called dynamical equivalence and makes network identification a hard problem to…

Dynamical Systems · Mathematics 2022-05-03 Abhishek Deshpande

In this paper we show that the dynamics of a class of kinetic compartmental models with bounded capacities, monotone reaction rates and a strongly connected interconnection structure is persistent. The result is based on the chemical…

Dynamical Systems · Mathematics 2022-01-25 G. Szederkenyi , B. Acs , Gy. Liptak , M. A. Vaghy

The recent discovery of universal principles underlying many complex networks occurring across a wide range of length scales in the biological world has spurred physicists in trying to understand such features using techniques from…

Biological Physics · Physics 2015-05-13 Sitabhra Sinha

We present a systematic mathematical analysis of the qualitative steady-state response to rate perturbations in large classes of reaction networks. This includes multimolecular reactions and allows for catalysis, enzymatic reactions,…

Dynamical Systems · Mathematics 2017-11-22 Bernhard Brehm , Bernold Fiedler

A reaction network together with a choice of rate constants uniquely gives rise to a system of differential equations, according to the law of mass-action kinetics. On the other hand, different networks can generate the same dynamical…

Dynamical Systems · Mathematics 2021-05-18 Gheorghe Craciun , Jiaxin Jin , Polly Y. Yu

We present a model of adaptive regulatory networks consisting of a simple biologically-motivated rewiring procedure coupled to an elementary stability criterion. The resulting networks exhibit a characteristic stationary heavy-tailed degree…

Physics and Society · Physics 2020-08-05 Ben D. MacArthur , Rubén J. Sánchez-García , Avi Ma'ayan

Chemical reaction networks (CRNs) provide a convenient language for modelling a broad variety of biological systems. These models are commonly studied with respect to the time series they generate in deterministic or stochastic simulations.…

Molecular Networks · Quantitative Biology 2019-07-11 Ozan Kahramanoğulları

Robustness of routing policies for networks is a central problem which is gaining increased attention with a growing awareness to safeguard critical infrastructure networks against natural and man-induced disruptions. Routing under limited…

Systems and Control · Computer Science 2012-05-02 Giacomo Como , Ketan Savla , Daron Acemoglu , Munther A. Dahleh , Emilio Frazzoli

A reaction network is a chemical system involving multiple reactions and chemical species. Stochastic models of such networks treat the system as a continuous time Markov chain on the number of molecules of each species with reactions as…

Probability · Mathematics 2007-05-23 Karen Ball , Thomas G. Kurtz , Lea Popovic , Greg Rempala

Many systems on our planet are known to shift abruptly and irreversibly from one state to another when they are forced across a "tipping point," such as mass extinctions in ecological networks, cascading failures in infrastructure systems,…

Quantitative Methods · Quantitative Biology 2022-05-23 Xueming Liu , Daqing Li , Manqing Ma , Boleslaw K. Szymanski , H Eugene Stanley , Jianxi Gao

In this essay, we investigate some relations between Chemical Reaction Networks (CRN) and Mathematical Epidemiology (ME) and report on several pleasant surprises which we had simply by putting these two topics together. Firstly, we propose…

Molecular Networks · Quantitative Biology 2025-05-22 Florin Avram , Rim Adenane , Andrei D. Halanay , Matthew D. Johnston

This work concerns the development of deep networks that are certifiably robust to adversarial attacks. Joint robust classification-detection was recently introduced as a certified defense mechanism, where adversarial examples are either…

Computer Vision and Pattern Recognition · Computer Science 2023-05-12 Sina Baharlouei , Fatemeh Sheikholeslami , Meisam Razaviyayn , Zico Kolter

A class of chemical reaction networks is described with the property that each positive equilibrium is locally asymptotically stable relative to its stoichiometry class, an invariant subspace on which it lies. The reaction systems treated…

Dynamical Systems · Mathematics 2013-04-11 Pete Donnell , Murad Banaji

Adaptation to dynamic conditions requires a certain degree of diversity. If all agents take the best current action, learning that the underlying state has changed and behavior should adapt will be slower. Diversity is harder to maintain…

Social and Information Networks · Computer Science 2023-05-02 Daron Acemoglu , Asuman Ozdaglar , Sarath Pattathil

The persistence conjecture is a long-standing open problem in chemical reaction network theory. It concerns the behavior of solutions to coupled ODE systems that arise from applying mass-action kinetics to a network of chemical reactions.…

Dynamical Systems · Mathematics 2014-10-07 Abhishek Deshpande , Manoj Gopalkrishnan
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