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The analysis of excursion sets in imaging data is essential to a wide range of scientific disciplines such as neuroimaging, climatology and cosmology. Despite growing literature, there is little published concerning the comparison of…

Methodology · Statistics 2022-01-11 Thomas Maullin-Sapey , Armin Schwartzman , Thomas E. Nichols

Capturing dynamic spatiotemporal neural activity is essential for understanding large-scale brain mechanisms. Functional magnetic resonance imaging (fMRI) provides high-resolution cortical representations that form a strong basis for…

Image and Video Processing · Electrical Eng. & Systems 2026-04-01 Wanying Qu , Jianxiong Gao , Wei Wang , Yanwei Fu

This paper presents an annotated dataset of brain MRI images designed to advance the field of brain symmetry study. Magnetic resonance imaging (MRI) has gained interest in analyzing brain symmetry in neonatal infants, and challenges remain…

Computer Vision and Pattern Recognition · Computer Science 2024-01-23 Arnaud Gucciardi , Safouane El Ghazouali , Francesca Venturini , Vida Groznik , Umberto Michelucci

For a long time, many methods are developed to make temporal signal analyses based on time series. However, for geographical systems, spatial signal analyses are as important as temporal signal analyses. Nonstationary spatial and temporal…

Physics and Society · Physics 2020-12-29 Yanguang Chen , Yuqing Long

Segmentation of Multiple Sclerosis (MS) lesions in longitudinal brain MR scans is performed for monitoring the progression of MS lesions. We hypothesize that the spatio-temporal cues in longitudinal data can aid the segmentation algorithm.…

Image and Video Processing · Electrical Eng. & Systems 2020-09-29 Stefan Denner , Ashkan Khakzar , Moiz Sajid , Mahdi Saleh , Ziga Spiclin , Seong Tae Kim , Nassir Navab

Most brain disorders are very heterogeneous in terms of their underlying biology and developing analysis methods to model such heterogeneity is a major challenge. A promising approach is to use probabilistic regression methods to estimate…

Machine Learning · Statistics 2018-12-03 Seyed Mostafa Kia , Christian F. Beckmann , Andre F. Marquand

Large language models (LLMs) and vision-language models (VLMs) have demonstrated remarkable performance across a wide range of tasks and domains. Despite this promise, spatial understanding and reasoning -- a fundamental component of human…

Computer Vision and Pattern Recognition · Computer Science 2024-11-06 Jiayu Wang , Yifei Ming , Zhenmei Shi , Vibhav Vineet , Xin Wang , Yixuan Li , Neel Joshi

Recent works have shown that Deep Recurrent Neural Networks using the LSTM architecture can achieve strong single-channel speech enhancement by estimating time-frequency masks. However, these models do not naturally generalize to…

Sound · Computer Science 2020-12-04 Felix Grezes , Zhaoheng Ni , Viet Anh Trinh , Michael Mandel

A common analytical problem in neuroscience is the interpretation of neural activity with respect to sensory input or behavioral output. This is typically achieved by regressing measured neural activity against known stimuli or behavioral…

Computation · Statistics 2016-06-28 Kamiar Rahnama Rad , Timothy A. Machado , Liam Paninski

Cardiac real-time magnetic resonance imaging (MRI) is an emerging technology that images the heart at up to 50 frames per second, offering insight into the respiratory effects on the heartbeat. However, this method significantly increases…

Brain activation mapping using functional MRI (fMRI) based on blood oxygenation level-dependent (BOLD) contrast has been conventionally focused on probing gray matter, the BOLD contrast in white matter having been generally disregarded.…

Signal Processing · Electrical Eng. & Systems 2019-10-25 David Abramian , Martin Larsson , Anders Eklund , Hamid Behjat

Representations from transformer-based unidirectional language models are known to be effective at predicting brain responses to natural language. However, most studies comparing language models to brains have used GPT-2 or similarly sized…

Computation and Language · Computer Science 2024-01-31 Richard Antonello , Aditya Vaidya , Alexander G. Huth

Bayesian whole-brain functional magnetic resonance imaging (fMRI) analysis with three-dimensional spatial smoothing priors has been shown to produce state-of-the-art activity maps without pre-smoothing the data. The proposed inference…

Methodology · Statistics 2020-10-02 Per Sidén , Finn Lindgren , David Bolin , Anders Eklund , Mattias Villani

Recent advances in multimodal large language models (LLMs) have enabled unified reasoning across images, audio, and video, but extending such capability to brain imaging remains largely unexplored. Bridging this gap is essential to link…

Computation and Language · Computer Science 2026-05-15 Yuxiang Wei , Yanteng Zhang , Xi Xiao , Chengxuan Qian , Tianyang Wang , Vince D. Calhoun

Quantitative characterization of cellular spatial organization is critical for understanding tumor progression and immune response. Recent advances in artificial intelligence (AI) enable large-scale segmentation and classification of nuclei…

Bayesian Image-on-Scalar Regression (ISR) provides flexible, uncertainty-aware neuroimaging analysis. However, applying ISR to large-scale datasets such as the UK Biobank is challenging due to intensive computational demands and the need to…

Applications · Statistics 2026-02-09 Yuliang Xu , Timothy D. Johnson , Thomas E. Nichols , Jian Kang

Important applications of advancements in machine learning, are in the area of healthcare, more so for neurological disorder detection. A crucial step towards understanding the neurological status, is to estimate the brain age using…

Image and Video Processing · Electrical Eng. & Systems 2024-07-10 Vamshi Krishna Kancharla , Neelam Sinha

Understanding how the brain represents the multifaceted properties of words in context is essential for explaining the neural architecture of human language. Here, we combine large-scale psycholinguistic modeling with naturalistic fMRI to…

Neurons and Cognition · Quantitative Biology 2026-01-21 Xuan Yang , Chuanji Gao , Cheng Xiao , Nicholas Riccardi , Rutvik H. Desai

Multimodal MRI offers complementary multi-scale information to characterize the brain structure. However, it remains challenging to effectively integrate multimodal MRI while achieving neuroscience interpretability. Here we propose to use…

Neurons and Cognition · Quantitative Biology 2025-12-15 Chengzhi Xia , Jianwei Chen , Yixuan Jiang , Qi Yan , Chao Li

Biological processes involve a variety of spatial and temporal scales. A holistic understanding of many biological processes therefore requires multi-scale models which capture the relevant properties on all these scales. In this manuscript…

Molecular Networks · Quantitative Biology 2015-06-23 Jan Hasenauer , Nick Jagiella , Sabrina Hross , Fabian J. Theis