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Whole Slide Image (WSI) analysis is a powerful method to facilitate the diagnosis of cancer in tissue samples. Automating this diagnosis poses various issues, most notably caused by the immense image resolution and limited annotations. WSIs…

Computer Vision and Pattern Recognition · Computer Science 2023-04-19 Ahmet Gokberk Gul , Oezdemir Cetin , Christoph Reich , Tim Prangemeier , Nadine Flinner , Heinz Koeppl

We present a self-supervised algorithm for several classification tasks within hematoxylin and eosin (H&E) stained images of breast cancer. Our method is robust to stain variations inherent to the histology images acquisition process, which…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Alexandre Tiard , Alex Wong , David Joon Ho , Yangchao Wu , Eliram Nof , Alvin C. Goh , Stefano Soatto , Saad Nadeem

Automated segmentation of cancer on medical images can aid targeted diagnostic and therapeutic procedures. However, its adoption is limited by the high cost of expert annotations required for training and inter-observer variability in…

Image and Video Processing · Electrical Eng. & Systems 2025-05-26 Lynn Karam , Yipei Wang , Veeru Kasivisvanathan , Mirabela Rusu , Yipeng Hu , Shaheer U. Saeed

Automated semantic segmentation of whole-slide images (WSIs) stained with hematoxylin and eosin (H&E) is essential for large-scale artificial intelligence-based biomarker analysis in breast cancer. However, existing public datasets for…

Along with the breakthrough of convolutional neural networks, learning-based segmentation has emerged in many research works. Most of them are based on supervised learning, requiring plenty of annotated data; however, to support…

Computer Vision and Pattern Recognition · Computer Science 2023-03-23 Junhuan Yang , Yi Sheng , Yuzhou Zhang , Weiwen Jiang , Lei Yang

With the development of multimodality and large language models, the deep learning-based technique for medical image captioning holds the potential to offer valuable diagnostic recommendations. However, current generic text and image…

Computer Vision and Pattern Recognition · Computer Science 2024-01-02 Zhenyu Zhang , Benlu Wang , Weijie Liang , Yizhi Li , Xuechen Guo , Guanhong Wang , Shiyan Li , Gaoang Wang

In this paper, we propose an unsupervised method for hyperspectral remote sensing image segmentation. The method exploits the mean-shift clustering algorithm that takes as input a preliminary hyperspectral superpixels segmentation together…

Computer Vision and Pattern Recognition · Computer Science 2022-10-10 Mirko Paolo Barbato , Paolo Napoletano , Flavio Piccoli , Raimondo Schettini

Medical images used in clinical practice are heterogeneous and not the same quality as scans studied in academic research. Preprocessing breaks down in extreme cases when anatomy, artifacts, or imaging parameters are unusual or protocols…

Image and Video Processing · Electrical Eng. & Systems 2022-08-31 Mostafa Mehdipour Ghazi , Mads Nielsen

While large language-image pre-trained models like CLIP offer powerful generic features for image clustering, existing methods typically freeze the encoder. This creates a fundamental mismatch between the model's task-agnostic…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Zihan Li , Wei Sun , Jing Hu , Jianhua Yin , Jianlong Wu , Liqiang Nie

Hyperspectral image classification demands spatially coherent predictions and precise boundary delineation. Yet prevailing superpixel-based methods face an inherent contradiction: clustering aggregates similar pixels into regions, but the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Peifu Liu , Tingfa Xu , Jie Wang , Huan Chen , Huiyan Bai , Jianan Li

Segmenting tumors in histological images is vital for cancer diagnosis. While fully supervised models excel with pixel-level annotations, creating such annotations is labor-intensive and costly. Accurate histopathology image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Yinsheng He , Xingyu Li , Roger J. Zemp

The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

Image and Video Processing · Electrical Eng. & Systems 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold

We present two practical improvement techniques for unsupervised segmentation learning. These techniques address limitations in the resolution and accuracy of predicted segmentation maps of recent state-of-the-art methods. Firstly, we…

Computer Vision and Pattern Recognition · Computer Science 2024-12-02 Alp Eren Sari , Francesco Locatello , Paolo Favaro

Image clustering is an important and open-challenging task in computer vision. Although many methods have been proposed to solve the image clustering task, they only explore images and uncover clusters according to the image features, thus…

Computer Vision and Pattern Recognition · Computer Science 2023-04-11 Shaotian Cai , Liping Qiu , Xiaojun Chen , Qin Zhang , Longteng Chen

Advancements in clinical treatment are increasingly constrained by the limitations of supervised learning techniques, which depend heavily on large volumes of annotated data. The annotation process is not only costly but also demands…

Computer Vision and Pattern Recognition · Computer Science 2024-05-20 Pranav Singh , Raviteja Chukkapalli , Shravan Chaudhari , Luoyao Chen , Mei Chen , Jinqian Pan , Craig Smuda , Jacopo Cirrone

Recent advances in whole-slide image (WSI) scanners and computational capabilities have significantly propelled the application of artificial intelligence in histopathology slide analysis. While these strides are promising, current…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Weiyi Wu , Chongyang Gao , Joseph DiPalma , Soroush Vosoughi , Saeed Hassanpour

Molecular subtyping of breast cancer is crucial for personalized treatment and prognosis. Traditional classification approaches rely on either histopathological images or gene expression profiling, limiting their predictive power. In this…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Amin Honarmandi Shandiz

Segmentation is a critical task in computational pathology, as it identifies areas affected by disease or abnormal growth and is essential for diagnosis and treatment. However, acquiring high-quality pixel-level supervised segmentation data…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Zhiling Yan , Sicheng Chen , Tianyi Zhang , Nan Ying , Yanli Lei , Guanglei Zhang

Semantic segmentation is crucial in remote sensing, where high-resolution satellite images are segmented into meaningful regions. Recent advancements in deep learning have significantly improved satellite image segmentation. However, most…

Computer Vision and Pattern Recognition · Computer Science 2024-08-07 Santiago Rivier , Carlos Hinojosa , Silvio Giancola , Bernard Ghanem

Several unsupervised image segmentation approaches have been proposed which eliminate the need for dense manually-annotated segmentation masks; current models separately handle either semantic segmentation (e.g., STEGO) or class-agnostic…

Computer Vision and Pattern Recognition · Computer Science 2023-12-29 Dantong Niu , Xudong Wang , Xinyang Han , Long Lian , Roei Herzig , Trevor Darrell