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Related papers: VaxEquity: A Data-Driven Risk Assessment and Optim…

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Predictive contagion models are ubiquitous in epidemiology, social sciences, engineering, and management. This paper formulates a prescriptive contagion analytics model where a decision-maker allocates shared resources across multiple…

Optimization and Control · Mathematics 2023-10-24 Alexandre Jacquillat , Michael Lingzhi Li , Martin Ramé , Kai Wang

Vaccines play a crucial role in the prevention and control of infectious diseases. However, the vaccine supply chain faces numerous challenges that hinder its efficiency. To address these challenges and enhance public health outcomes, many…

Theoretical Economics · Economics 2025-10-07 Ran Gu , Enhui Ding , Shigui Ma

This study presents a mathematical model for optimal vaccination strategies in interconnected metropolitan areas, considering commuting patterns. It is a compartmental model with a vaccination rate for each city, acting as a control…

Populations and Evolution · Quantitative Biology 2024-04-29 Lucas Machado Moschen , María Soledad Aronna

The COVID-19 pandemic has so far accounted for reported 5.5M deaths worldwide, with 8.7% of these coming from India. The pandemic exacerbated the weakness of the Indian healthcare system. As of January 20, 2022, India is the second worst…

Computers and Society · Computer Science 2022-06-07 Tanvi Karandikar , Avinash Prabhu , Mehul Mathur , Megha Arora , Hemank Lamba , Ponnurangam Kumaraguru

The COVID-19 pandemic has severely affected the world in terms of health, economy and peace. Fortunately, the countries are trying to overcome the situation by actively carrying out vaccinations. However, like any other massive operation…

Cryptography and Security · Computer Science 2024-12-03 Sankha Das , Amit Dua

Many stochastic optimization problems include chance constraints that enforce constraint satisfaction with a specific probability; however, solving an optimization problem with chance constraints assumes that the solver has access to the…

Optimization and Control · Mathematics 2021-09-21 Joshua Comden , Ahmed S. Zamzam , Andrey Bernstein

Voluntary vaccination is essential to protect oneself from infection and suppress the spread of infectious diseases. Voluntary vaccination behavior is influenced by factors such as age and interaction patterns. Differences in health…

Physics and Society · Physics 2024-12-11 Yanyi Nie , Tao Lin , Yanbing Liu , Wei Wang

This paper considers a risk-constrained infinite-horizon optimal control problem and proposes to solve it in an iterative manner. Each iteration of the algorithm generates a trajectory from the starting point to the target equilibrium state…

Optimization and Control · Mathematics 2021-11-29 Alireza Zolanvari , Ashish Cherukuri

In the context of SARS-CoV-2 pandemic, mathematical modelling has played a fundamental role for making forecasts, simulating scenarios and evaluating the impact of preventive political, social and pharmaceutical measures. Optimal control…

Optimization and Control · Mathematics 2022-11-01 Giovanni Ziarelli , Luca Dede' , Nicola Parolini , Marco Verani , Alfio Quarteroni

The COVID-19 pandemic has adversely affected US public health, resulting in over a hundred million cases and more than one million deaths. Vaccination is the key intervention against the COVID-19 pandemic. Multiple COVID-19 vaccines are now…

Applications · Statistics 2025-02-25 Asim K. Dey

Vaccination has played an important role in preventing the spread of infectious diseases. However, the limited availability of vaccines and personnel at the roll-out of a new vaccine and the costs of vaccination campaigns often limit how…

Physics and Society · Physics 2026-01-27 Rowan Hoogervorst , Evelien van der Hurk , David Pisinger

Predicting an individual's risk of experiencing a future clinical outcome is a statistical task with important consequences for both practicing clinicians and public health experts. Modern observational databases such as electronic health…

This work proposes a scalable, blockchain-based platform for the secure sharing of COVID-19 or other disease vaccination certificates. As an indicative use case, we simulate a large-scale deployment by considering the countries of the…

The paper provides a framework for the assessment and optimization of the total risk of complex distributed systems. The framework takes into account the risk of each agent, which may arise from heterogeneous sources, as well as the risk…

Optimization and Control · Mathematics 2025-09-09 Aray Almen , Darinka Dentcheva

Estimates of national immunization coverage are crucial for guiding policy and decision-making in national immunization programs and setting the global immunization agenda. WHO and UNICEF estimates of national immunization coverage (WUENIC)…

We propose a distributionally robust logistic regression model with an unfairness penalty that prevents discrimination with respect to sensitive attributes such as gender or ethnicity. This model is equivalent to a tractable convex…

Machine Learning · Computer Science 2020-07-21 Bahar Taskesen , Viet Anh Nguyen , Daniel Kuhn , Jose Blanchet

For time-to-event data with finitely many competing risks, the proportional hazards model has been a popular tool for relating the cause-specific outcomes to covariates [Prentice et al. Biometrics 34 (1978) 541--554]. This article studies…

Statistics Theory · Mathematics 2009-03-04 Yanqing Sun , Peter B. Gilbert , Ian W. McKeague

Data-driven decision-making under uncertainty typically presumes the collection of historical data from an unknown target probability distribution. However, one may have no access to any data from the target distribution prior to…

Optimization and Control · Mathematics 2026-04-23 Xianyu Li , Huan Xu , Xiaolin Huang , Chao Shang

Vaccination policies play a central role in public health interventions and models are often used to assess the effectiveness of these policies. Many vaccines are leaky, in which case the observed vaccine effectiveness depends on the force…

Populations and Evolution · Quantitative Biology 2025-04-21 Gray Manicom , Emily Harvey , Joshua Looker , David Wu , Oliver Maclaren , Dion O' Neale

A pandemic poses particular challenges to decision-making because of the need to continuously adapt decisions to rapidly changing evidence and available data. For example, which countermeasures are appropriate at a particular stage of the…

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