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Related papers: VaxEquity: A Data-Driven Risk Assessment and Optim…

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The optimal allocation of vaccines to population subgroups over time is a challenging health care management problem. In the context of a pandemic, the interaction between vaccination policies adopted by multiple agents and the cooperation…

Optimization and Control · Mathematics 2021-09-22 David Rey , Ahmed W Hammad , Meead Saberi

The COVID-19 vaccine development, manufacturing, transportation, and administration proved an extreme logistics operation of global magnitude. Global vaccination levels, however, remain a key concern in preventing the emergence of new…

General Economics · Economics 2025-01-10 Sharika J. Hegde , Max T. M. Ng , Marcos Rios , Hani S. Mahmassani , Ying Chen , Karen Smilowitz

With the approval of vaccines for the coronavirus disease by many countries worldwide, most developed nations have begun, and developing nations are gearing up for the vaccination process. This has created an urgent need to provide a…

Computers and Society · Computer Science 2021-02-09 Mahzabeen Emu , Dhivya Chandrasekaran , Vijay Mago , Salimur Choudhury

Balancing social utility and equity in distributing limited vaccines represents a critical policy concern for protecting against the prolonged COVID-19 pandemic. What is the nature of the trade-off between maximizing collective welfare and…

Computers and Society · Computer Science 2021-11-15 Lin Chen , Fengli Xu , Zhenyu Han , Kun Tang , Pan Hui , James Evans , Yong Li

The COVID-19 pandemic has led to a need for widespread and rapid vaccine development. As several vaccines have recently been approved for human use or are in different stages of development, governments across the world are preparing…

The outbreak of COVID-19 led to a record-breaking race to develop a vaccine. However, the limited vaccine capacity creates another massive challenge: how to distribute vaccines to mitigate the near-end impact of the pandemic? In the United…

Populations and Evolution · Quantitative Biology 2021-07-20 Dimitris Bertsimas , Vassilis Digalakis , Alexander Jacquillat , Michael Lingzhi Li , Alessandro Previero

Purpose: Only few companies were able to produce vaccine again COVID-19. Thus, one producer supplied it to many countries. The distribution was not effective. Some countries overstocked the vaccine while other countries were not able to buy…

Physics and Society · Physics 2024-08-20 Béla Vizvári , Gergely Kovács

We develop a model of infection spread that takes into account the existence of a vulnerable group as well as the variability of the social relations of individuals. We develop a compartmentalized power-law model, with power-law connections…

Physics and Society · Physics 2020-10-13 Simone Santini

Epidemic risk assessment poses inherent challenges, with traditional approaches often failing to balance health outcomes and economic constraints. This paper presents a data-driven decision support tool that models epidemiological dynamics…

Applications · Statistics 2025-11-24 Chang Zhai , Ping Chen , Zhuo Jin , David Pitt

Vaccinations against viruses have always been the need of the hour since long past. However, it is hard to efficiently distribute the vaccines (on time) to all the corners of a country, especially during a pandemic. Considering the vastness…

Machine Learning · Computer Science 2022-08-03 Jayeeta Mondal , Jeet Dutta , Hrishav Bakul Barua

During various stages of the COVID-19 pandemic, countries implemented diverse vaccine management approaches, influenced by variations in infrastructure and socio-economic conditions. This article provides a comprehensive overview of…

Optimization and Control · Mathematics 2024-05-27 Shibshankar Dey , Ali Kaan Kurbanzade , Esma S. Gel , Joseph Mihaljevic , Sanjay Mehrotra

In this paper, we present a decision support framework for optimizing multiple aspects of vaccine distribution across a multitier cold chain network. We propose two multi-period optimization formulations within this framework: first to…

Physics and Society · Physics 2022-01-12 Shanmukhi Sripada , Ayush Jain , Prasanna Ramamoorthy , Varun Ramamohan

Since early 2020, the world has been dealing with a raging pandemic outbreak: COVID-19. A year later, vaccines have become accessible, but in limited quantities, so that governments needed to devise a strategy to decide which part of the…

Populations and Evolution · Quantitative Biology 2022-04-13 Sander Tonkens , Paul de Klaver , Mauro Salazar

We propose a mathematical framework, based on conic geometric programming, to control a susceptible-infected-susceptible viral spreading process taking place in a directed contact network with unknown contact rates. We assume that we have…

Optimization and Control · Mathematics 2014-12-09 Shuo Han , Victor M. Preciado , Cameron Nowzari , George J. Pappas

Covid-19 has caused hundred of thousands of deaths and an economic damage amounting to trillions of dollars, creating a desire for the rapid development of vaccine. Once available, vaccine is gradually produced, evoking the question on how…

Populations and Evolution · Quantitative Biology 2020-06-30 Jens Grauer , Hartmut Löwen , Benno Liebchen

Massive vaccination against pandemics such as Coronavirus SARS-CoV-2 presents several complexities. The criteria to assess public health policies are fundamental to distribute vaccines in an effective way in order to avoid as many…

Optimization and Control · Mathematics 2023-12-01 José Luis Sainz-Pardo , José Valero

Timely and effective decision-making is critical during epidemics to reduce preventable infections and deaths. This demands integrated models that jointly capture disease dynamics, vaccine distribution, regional disparities, and behavioral…

Social and Information Networks · Computer Science 2025-11-26 Kimiya Jozani , Nihal A. Sageer , Hode Eldardiry , Sait Tunc , Esra Buyuktahtakin Toy

The pandemic caused by the SARS-CoV-2 virus has exposed many flaws in the decision-making strategies used to distribute resources to combat global health crises. In this paper, we leverage reinforcement learning and optimization to improve…

Artificial Intelligence · Computer Science 2021-01-06 Lawrence Thul , Warren Powell

The global SARS-CoV-2 (COVID-19) pandemic highlighted the challenge of equitable vaccine distribution between high- and low-income countries. Many high-income countries were reluctant or slow to distribute extra doses of the vaccine to…

Populations and Evolution · Quantitative Biology 2024-08-21 Abraham Holleran , Susan E. Martonosi , Michael Veatch

In a world being hit by waves of COVID-19, vaccination is a light on the horizon. However, the roll-out of vaccination strategies and their influence on the pandemic are still open problems. In order to compare the effect of various…

Physics and Society · Physics 2021-04-23 N. L. Barreiro , C. I. Ventura , T. Govezensky , M. Núñez , P. G. Bolcatto , R. A. Barrio
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