Related papers: Critical periods and Autism Spectrum Disorders, a …
Brain rhythms contribute to every aspect of brain function. Here, we study critical and resonance phenomena that precede the emergence of brain rhythms. Using an analytical approach and simulations of a cortical circuit model of neural…
Autism Spectrum Disorder (ASD) is characterized by challenges with social interaction and communication and by restricted or repetitive patterns of thought and behavior, with significant variability in presentation. Approximately a quarter…
Spike-timing-dependent plasticity (STDP) with asymmetric learning windows is commonly found in the brain and useful for a variety of spike-based computations such as input filtering and associative memory. A natural consequence of STDP is…
A sleep forecast allows individuals and healthcare providers to anticipate and proactively address factors influencing restful rest, ultimately improving mental and physical well-being. This work presents an adaptive spatial and temporal…
Critical slowing down (CSD) has been a trademark of critical dynamics for equilibrium phase transitions of a many-body system, where the relaxation time for the system to reach thermal equilibrium or quantum ground state diverges with…
Refractory periods are an unavoidable feature of excitable elements, resulting in necessary time-lags for re-excitation. Herein, we measure neuronal absolute refractory periods (ARPs) in synaptic blocked neuronal cultures. In so doing, we…
Diagnostic procedures for ASD (autism spectrum disorder) involve semi-naturalistic interactions between the child and a clinician. Computational methods to analyze these sessions require an end-to-end speech and language processing pipeline…
Brain plasticity refers to brain's ability to change neuronal connections, as a result of environmental stimuli, new experiences, or damage. In this work, we study the effects of the synaptic delay on both the coupling strengths and…
The traditional methods for detecting autism spectrum disorder (ASD) are expensive, subjective, and time-consuming, often taking years for a diagnosis, with many children growing well into adolescence and even adulthood before finally…
Although there is increasing evidence of criticality in the brain, the processes that guide neuronal networks to reach or maintain criticality remain unclear. The present research examines the role of neuronal gain plasticity in time-series…
Sleep traits are shaped by genetic and environmental factors and may influence many health conditions. The All of Us Research Program, which includes EHR, physical measurements, genomic data, and wearable data across ancestry groups,…
Sleep is particularly important to the health of infants, children, and adolescents, and sleep scoring is the first step to accurate diagnosis and treatment of potentially life-threatening conditions. But pediatric sleep is severely…
We show that the local Spike Timing-Dependent Plasticity (STDP) rule has the effect of regulating the trans-synaptic weights of loops of any length within a simulated network of neurons. We show that depending on STDP's polarity, functional…
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder (NDD) that is caused by genetic, epigenetic, and environmental factors. Recent advances in genomic analysis have uncovered numerous candidate genes with common…
The interplay between structure and function is crucial in determining some emerging properties of many natural systems. Here we use an adaptive neural network model inspired in observations of synaptic pruning that couples activity and…
The critical brain hypothesis posits that neural systems operate near a phase transition, optimizing the processing of information. While scale invariance and non-Gaussian dynamics--hallmarks of criticality--have been observed in brain…
Autism Spectrum Disorder (ASD) is a multi-factorial neurodevelopmental disorder, whose causes are still poorly understood. Effective therapies to reduce all the heterogeneous symptoms of the disorder do not exists yet, but behavioural…
Autism Spectrum Disorder (ASD) represents a multifaceted neurodevelopmental condition marked by difficulties in social interaction, communication impediments, and repetitive behaviors. Despite progress in understanding ASD, its diagnosis…
Socially assistive robotics (SAR) research has shown great potential for supplementing and augmenting therapy for children with autism spectrum disorders (ASD). However, the vast majority of SAR research has been limited to short-term…
Autism Spectrum Disorder (ASD) is a prevalent neurological disorder. However, the multi-faceted symptoms and large individual differences among ASD patients are hindering the diagnosis process, which largely relies on subject descriptions…