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Convolutional neural networks (CNNs) have been recently used for a variety of histology image analysis. However, availability of a large dataset is a major prerequisite for training a CNN which limits its use by the computational pathology…

Computer Vision and Pattern Recognition · Computer Science 2018-03-07 Ruqayya Awan , Navid Alemi Koohbanani , Muhammad Shaban , Anna Lisowska , Nasir Rajpoot

Model explainability is essential for the creation of trustworthy Machine Learning models in healthcare. An ideal explanation resembles the decision-making process of a domain expert and is expressed using concepts or terminology that is…

Machine Learning · Computer Science 2021-07-14 Sumedha Singla , Stephen Wallace , Sofia Triantafillou , Kayhan Batmanghelich

Interpretable machine learning has emerged as central in leveraging artificial intelligence within high-stakes domains such as healthcare, where understanding the rationale behind model predictions is as critical as achieving high…

Machine Learning · Computer Science 2024-04-30 Christel Sirocchi , Martin Urschler , Bastian Pfeifer

Breast cancer (BC) remains a significant health threat, with no long-term cure currently available. Early detection is crucial, yet mammography interpretation is hindered by high false positives and negatives. With BC incidence projected to…

Computer Vision and Pattern Recognition · Computer Science 2023-06-22 Jai Vardhan , Taraka Satya Krishna Teja Malisetti

Gene and protein networks are very important to model complex large-scale systems in molecular biology. Inferring or reverseengineering such networks can be defined as the process of identifying gene/protein interactions from experimental…

Machine Learning · Computer Science 2017-03-10 Stefano Beretta , Mauro Castelli , Ivo Goncalves , Ivan Merelli , Daniele Ramazzotti

Cervical cancer, the fourth leading cause of cancer in women globally, requires early detection through Pap smear tests to identify precancerous changes and prevent disease progression. In this study, we performed a focused analysis by…

Image and Video Processing · Electrical Eng. & Systems 2025-05-22 Abdul Samad Shaik , Shashaank Mattur Aswatha , Rahul Jashvantbhai Pandya

In this work, we present a deep learning framework for multi-class breast cancer image classification as our submission to the International Conference on Image Analysis and Recognition (ICIAR) 2018 Grand Challenge on BreAst Cancer…

Computer Vision and Pattern Recognition · Computer Science 2018-02-06 Yeeleng S. Vang , Zhen Chen , Xiaohui Xie

With the increase in the use of deep learning for computer-aided diagnosis in medical images, the criticism of the black-box nature of the deep learning models is also on the rise. The medical community needs interpretable models for both…

Image and Video Processing · Electrical Eng. & Systems 2020-12-21 Mookund Sureka , Abhijeet Patil , Deepak Anand , Amit Sethi

Breast cancer is one of the most common causes of cancer-related death in women worldwide. Early and accurate diagnosis of breast cancer may significantly increase the survival rate of patients. In this study, we aim to develop a fully…

Image and Video Processing · Electrical Eng. & Systems 2019-09-27 Sara Hosseinzadeh Kassani , Peyman Hosseinzadeh Kassani , Michal J. Wesolowski , Kevin A. Schneider , Ralph Deters

Deep learning has introduced several learning-based methods to recognize breast tumours and presents high applicability in breast cancer diagnostics. It has presented itself as a practical installment in Computer-Aided Diagnostic (CAD)…

Image and Video Processing · Electrical Eng. & Systems 2022-02-15 Timothy Kwong , Samaneh Mazaheri

In recent years Artificial Intelligence has emerged as a fundamental tool in medical applications. Despite this rapid development, deep neural networks remain black boxes that are difficult to explain, and this represents a major limitation…

Image and Video Processing · Electrical Eng. & Systems 2024-05-22 Tommaso Torda , Andrea Ciardiello , Simona Gargiulo , Greta Grillo , Simone Scardapane , Cecilia Voena , Stefano Giagu

Explainability is critical for deep learning applications in healthcare which are mandated to provide interpretations to both patients and doctors according to legal regulations and responsibilities. Explainable AI methods, such as feature…

Image and Video Processing · Electrical Eng. & Systems 2023-11-01 Jinze Zhao

Deep learning has demonstrated expert-level performance in melanoma classification, positioning it as a powerful tool in clinical dermatology. However, model opacity and the lack of interpretability remain critical barriers to clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Junwen Zheng , Xinran Xu , Li Rong Wang , Chang Cai , Lucinda Siyun Tan , Dingyuan Wang , Hong Liang Tey , Xiuyi Fan

The opaque nature of deep learning models remains a significant barrier to their clinical adoption in medical imaging. This paper presents a multimodal explainability framework that bridges the gap between convolutional neural network (CNN)…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Paul Valery Nguezet , Elie Tagne Fute , Yusuf Brima , Benoit Martin Azanguezet , Marcellin Atemkeng

Breast cancer investigation is of great significance, and developing tumor detection methodologies is a critical need. However, it is a challenging task for breast ultrasound due to the complicated breast structure and poor quality of the…

Computer Vision and Pattern Recognition · Computer Science 2019-10-24 Fei Xu , Yingtao Zhang , Min Xian , H. D. Cheng , Boyu Zhang , Jianrui Ding , Chunping Ning , Ying Wang

Deep Learning (DL) holds enormous potential for improving medical imaging diagnostics, yet the lack of interpretability in most models hampers clinical trust and adoption. This paper presents an explainable deep learning framework for…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Sai Teja Erukude , Viswa Chaitanya Marella , Suhasnadh Reddy Veluru

Deep learning models designed for visual classification tasks on natural images have become prevalent in medical image analysis. However, medical images differ from typical natural images in many ways, such as significantly higher…

Machine Learning · Computer Science 2019-08-21 Yiqiu Shen , Nan Wu , Jason Phang , Jungkyu Park , Gene Kim , Linda Moy , Kyunghyun Cho , Krzysztof J. Geras

Breast cancer is one of the leading causes of death globally, and thus there is an urgent need for early and accurate diagnostic techniques. Although ultrasound imaging is a widely used technique for breast cancer screening, it faces…

Image and Video Processing · Electrical Eng. & Systems 2025-02-11 Pandiyaraju V , Shravan Venkatraman , Pavan Kumar S , Santhosh Malarvannan , Kannan A

Breast histology image classification is a crucial step in the early diagnosis of breast cancer. In breast pathological diagnosis, Convolutional Neural Networks (CNNs) have demonstrated great success using digitized histology slides.…

Computer Vision and Pattern Recognition · Computer Science 2021-08-25 Zakaria Senousy , Mohammed M. Abdelsamea , Mohamed Medhat Gaber , Moloud Abdar , U Rajendra Acharya , Abbas Khosravi , Saeid Nahavandi

Nowadays, Breast cancer has risen to become one of the most prominent causes of death in recent years. Among all malignancies, this is the most frequent and the major cause of death for women globally. Manually diagnosing this disease…

Machine Learning · Computer Science 2022-07-01 Taminul Islam , Arindom Kundu , Nazmul Islam Khan , Choyon Chandra Bonik , Flora Akter , Md Jihadul Islam