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We propose a new dynamic SIR model that, in contrast with the available model on time scales, is biological relevant. For the new SIR model we obtain an explicit solution, we prove the asymptotic stability of the extinction and disease-free…

Physics and Society · Physics 2025-11-14 Márcia Lemos-Silva , Sandra Vaz , Delfim F. M. Torres

Non-adaptive group testing refers to the problem of inferring a sparse set of defectives from a larger population using the minimum number of simultaneous pooled tests. Recent positive results for noiseless group testing have motivated the…

Information Theory · Computer Science 2021-07-16 Gabriel Arpino , Nicolò Grometto , Afonso S. Bandeira

In many scenarios such as genome-wide association studies where dependences between variables commonly exist, it is often of interest to infer the interaction effects in the model. However, testing pairwise interactions among millions of…

Methodology · Statistics 2022-09-02 Jingyi Duan , Yang Ning , Xi Chen , Yong Chen

To better predict the dynamics of epidemics such as COVID-19, it is important not only to investigate the network of local and long-range contagious contacts but also to understand the temporal dynamics of infectiousness and detectable…

Populations and Evolution · Quantitative Biology 2025-09-03 Miguel A. Cajahuanca Ricaldi , Yaroslav Ispolatov

Model-based recursive partitioning (MOB) is a semi-parametric statistical approach allowing the identification of subgroups that can be combined with a broad range of outcome measures including continuous time-to-event outcomes. When time…

Methodology · Statistics 2022-09-15 Cynthia Huber , Matthias Schmid , Tim Friede

Much effort has been directed towards using mathematical models to understand and predict contagious disease, in particular Ebola outbreaks. Classical SIR (susceptible-infected-recovered) compartmental models capture well the dynamics of…

Populations and Evolution · Quantitative Biology 2015-12-22 Anca Radulescu , Joanna Herron

In this study, we present an integro-differential model to simulate the local spread of infections. The model incorporates a standard susceptible-infected-recovered (\textit{SIR}-) model enhanced by an integral kernel, allowing for…

Dynamical Systems · Mathematics 2023-07-20 Moritz Schäfer , Karol Niedzielewski , Thomas Götz , Tyll Krüger

Detection of defective members of large populations has been widely studied in the statistics community under the name "group testing", a problem which dates back to World War II when it was suggested for syphilis screening. There the main…

Information Theory · Computer Science 2009-09-28 Mahdi Cheraghchi , Ali Hormati , Amin Karbasi , Martin Vetterli

In this article, we model and study the spread of COVID-19 in Germany, Japan, India and highly impacted states in India, i.e., in Delhi, Maharashtra, West Bengal, Kerala and Karnataka. We consider recorded data published in Worldometers and…

Physics and Society · Physics 2022-03-15 Ian Cooper , Argha Mondal , Chris G. Antonopoulos , Arindam Mishra

In group testing, the task is to identify defective items by testing groups of them together using as few tests as possible. We consider the setting where each item is defective with a constant probability $\alpha$, independent of all other…

Discrete Mathematics · Computer Science 2024-11-15 Lukas Hintze , Lena Krieg , Olga Scheftelowitsch , Haodong Zhu

An optimal dynamic treatment regime (DTR) is a sequence of decision rules aimed at providing the best course of treatments individualized to patients. While conventional DTR estimation uses longitudinal data, such data can also be…

Methodology · Statistics 2025-02-06 Larry Dong , Eleanor Pullenayegum , Rodolphe Thiébaut , Olli Saarela

The COVID-19 pandemic poses challenges for continuing economic activity while reducing health risks. While these challenges can be mitigated through testing, testing budget is often limited. Here we study how institutions, such as nursing…

Physics and Society · Physics 2021-01-05 Janni Yuval , Mor Nitzan , Neta Ravid Tannenbaum , Boaz Barak

We consider the SIR model and study the first time the number of infected individuals begins to decrease and the first time this population is below a given threshold. We interpret these times as functions of the initial susceptible and…

Classical Analysis and ODEs · Mathematics 2020-09-23 Ryan Hynd , Dennis Ikpe , Terrance Pendleton

We introduce a kinetic framework for modeling the time evolution of the statistical distributions of the population densities in the three compartments of susceptible, infectious, and recovered individuals, under epidemic spreading driven…

Analysis of PDEs · Mathematics 2025-12-16 Giorgio Martalò , Giuseppe Toscani , Mattia Zanella

In this paper, we propose a continuous-time stochastic intensity model, namely, two-phase dynamic contagion process(2P-DCP), for modelling the epidemic contagion of COVID-19 and investigating the lockdown effect based on the dynamic…

Physics and Society · Physics 2020-06-30 Zezhun Chen , Angelos Dassios , Valerie Kuan , Jia Wei Lim , Yan Qu , Budhi Surya , Hongbiao Zhao

There are multiple testing methods to ascertain an infection in an individual and they vary in their performances, cost and delay. Unfortunately, better performing tests are sometimes costlier and time consuming and can only be done for a…

Social and Information Networks · Computer Science 2021-06-17 Harish Sasikumar , Manoj Varma

We study a susceptible-infected-recovered (SIR) epidemic model on a network of $n$ interacting subpopulations. We analyze the transient and asymptotic behavior of the infection dynamics in each node of the network. In contrast to the…

Dynamical Systems · Mathematics 2024-03-18 Martina Alutto , Leonardo Cianfanelli , Giacomo Como , Fabio Fagnani

In epidemic or pandemic situations, resources for testing the infection status of individuals may be scarce. Although group testing can help to significantly increase testing capabilities, the (repeated) testing of entire populations can…

Populations and Evolution · Quantitative Biology 2021-10-29 Günther Koliander , Georg Pichler

Clinicians and researchers alike are increasingly interested in how best to personalize interventions. A dynamic treatment regimen (DTR) is a sequence of pre-specified decision rules which can be used to guide the delivery of a sequence of…

In this work we introduce a differential equation model with time-delay that describes the three-stage dynamics and the two time scales observed in HIV infection. Assuming that the virus has high mutation and rapid reproduction rates that…

Biological Physics · Physics 2015-03-13 Flora S. Bacelar , Roberto F. S. Andrade , Rita M. Zorzenon dos Santos