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Medical image segmentation is a fundamental and critical step in many image-guided clinical approaches. Recent success of deep learning-based segmentation methods usually relies on a large amount of labeled data, which is particularly…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Rushi Jiao , Yichi Zhang , Le Ding , Rong Cai , Jicong Zhang

A multi-reader multi-case (MRMC) analysis is applied to account for both reader and case variability when evaluating the clinical performance of a medical imaging device or reader performance under different reading modalities. For a…

Quantitative Methods · Quantitative Biology 2023-12-27 Si Wen , Brandon D. Gallas

The framework of variational autoencoders allows us to efficiently learn deep latent-variable models, such that the model's marginal distribution over observed variables fits the data. Often, we're interested in going a step further, and…

Machine Learning · Statistics 2020-12-22 Ilyes Khemakhem , Diederik P. Kingma , Ricardo Pio Monti , Aapo Hyvärinen

Combining multi-site data can strengthen and uncover trends, but is a task that is marred by the influence of site-specific covariates that can bias the data and therefore any downstream analyses. Post-hoc multi-site correction methods…

Image and Video Processing · Electrical Eng. & Systems 2021-11-09 Pedro Borges , Richard Shaw , Thomas Varsavsky , Kerstin Klaser , David Thomas , Ivana Drobnjak , Sebastien Ourselin , M Jorge Cardoso

Machine learning has been widely adopted for medical image analysis in recent years given its promising performance in image segmentation and classification tasks. The success of machine learning, in particular supervised learning, depends…

Computer Vision and Pattern Recognition · Computer Science 2022-06-03 Chengliang Dai , Shuo Wang , Yuanhan Mo , Elsa Angelini , Yike Guo , Wenjia Bai

Recent advances in Neural Variational Inference allowed for a renaissance in latent variable models in a variety of domains involving high-dimensional data. While traditional variational methods derive an analytical approximation for the…

Machine Learning · Computer Science 2019-08-20 Alexander I. Cowen-Rivers , Pasquale Minervini , Tim Rocktaschel , Matko Bosnjak , Sebastian Riedel , Jun Wang

In this work, we explore the issue of the inter-annotator agreement for training and evaluating automated segmentation of skin lesions. We explore what different degrees of agreement represent, and how they affect different use cases for…

Computer Vision and Pattern Recognition · Computer Science 2019-06-07 Vinicius Ribeiro , Sandra Avila , Eduardo Valle

Medical image segmentation annotations suffer from inter- and intra-observer variations even among experts due to intrinsic differences in human annotators and ambiguous boundaries. Leveraging a collection of annotators' opinions for an…

Image and Video Processing · Electrical Eng. & Systems 2021-05-04 Zahra Mirikharaji , Kumar Abhishek , Saeed Izadi , Ghassan Hamarneh

Maternal-fetal Ultrasound is the primary modality for monitoring fetal development, yet automated segmentation remains challenging due to the scarcity of high-quality annotations. To address this limitation, we propose a semi-supervised…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Fangyijie Wang , Guénolé Silvestre , Kathleen M. Curran

Manual annotation of medical images is highly subjective, leading to inevitable and huge annotation biases. Deep learning models may surpass human performance on a variety of tasks, but they may also mimic or amplify these biases. Although…

Computer Vision and Pattern Recognition · Computer Science 2022-03-23 Zehui Liao , Shishuai Hu , Yutong Xie , Yong Xia

Automated detection of anatomical landmarks plays a crucial role in many diagnostic and surgical applications. Progresses in deep learning (DL) methods have resulted in significant performance enhancement in tasks related to anatomical…

Image and Video Processing · Electrical Eng. & Systems 2024-11-28 Soorena Salari , Hassan Rivaz , Yiming Xiao

How can we perform efficient inference and learning in directed probabilistic models, in the presence of continuous latent variables with intractable posterior distributions, and large datasets? We introduce a stochastic variational…

Machine Learning · Statistics 2022-12-13 Diederik P Kingma , Max Welling

This article focuses on covariance estimation for multi-view data. Popular approaches rely on factor-analytic decompositions that have shared and view-specific latent factors. Posterior computation is conducted via expensive and brittle…

Methodology · Statistics 2026-04-20 Lorenzo Mauri , David B. Dunson

Segmentation tasks in medical imaging are inherently ambiguous: the boundary of a target structure is oftentimes unclear due to image quality and biological factors. As such, predicted segmentations from deep learning algorithms are…

Image and Video Processing · Electrical Eng. & Systems 2019-11-18 Katharina Hoebel , Ken Chang , Jay Patel , Praveer Singh , Jayashree Kalpathy-Cramer

Segmentation of anatomical structures is a fundamental image analysis task for many applications in the medical field. Deep learning methods have been shown to perform well, but for this purpose large numbers of manual annotations are…

Computer Vision and Pattern Recognition · Computer Science 2019-12-24 Firat Ozdemir , Zixuan Peng , Philipp Fuernstahl , Christine Tanner , Orcun Goksel

In the domain of medical imaging, many supervised learning based methods for segmentation face several challenges such as high variability in annotations from multiple experts, paucity of labelled data and class imbalanced datasets. These…

Computer Vision and Pattern Recognition · Computer Science 2025-05-15 Soumick Chatterjee , Franziska Gaidzik , Alessandro Sciarra , Hendrik Mattern , Gábor Janiga , Oliver Speck , Andreas Nürnberger , Sahani Pathiraja

We present a foundation model for brain MRI that can work with different combinations of imaging sequences. The model uses one encoder with learnable modality embeddings, conditional layer normalization, and a masked autoencoding objective…

Computer Vision and Pattern Recognition · Computer Science 2025-11-06 Minh Sao Khue Luu , Bair N. Tuchinov

Medical image annotation is a major hurdle for developing precise and robust machine learning models. Annotation is expensive, time-consuming, and often requires expert knowledge, particularly in the medical field. Here, we suggest using…

Computer Vision and Pattern Recognition · Computer Science 2020-09-28 Holger R Roth , Dong Yang , Ziyue Xu , Xiaosong Wang , Daguang Xu

Semi-supervised segmentation tackles the scarcity of annotations by leveraging unlabeled data with a small amount of labeled data. A prominent way to utilize the unlabeled data is by consistency training which commonly uses a…

Computer Vision and Pattern Recognition · Computer Science 2022-03-14 Sukesh Adiga , Jose Dolz , Herve Lombaert

The task of inferring high-level causal variables from low-level observations, commonly referred to as causal representation learning, is fundamentally underconstrained. As such, recent works to address this problem focus on various…

Machine Learning · Statistics 2024-03-26 Simon Bing , Urmi Ninad , Jonas Wahl , Jakob Runge
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