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The expected growth in wind energy capacity requires efficient and accurate models for wind farm layout optimization, control, and annual energy predictions. Although analytical wake models are widely used for these applications, several…

Fluid Dynamics · Physics 2023-02-16 Frederik Aerts , Luca Lanzilao , Johan Meyers

The clinical application of patient-specific modelling of the heart can provide valuable insights in supplementing and advancing methods of diagnosis as well as helping to devise the best possible therapeutic approach for each individual…

Medical Physics · Physics 2023-08-03 Sebastian Skatulla , Carlo Sansour , Mary Familusi , Jagir Hussan , Ntobeko Ntusi

Recent developments in cardiovascular modelling allow us to simulate blood flow in an entire human body. Such model can also be used to create databases of virtual subjects, with sizes limited only by computational resources. In this work,…

Medical Physics · Physics 2020-07-01 Janne M. J. Huttunen , Leo Kärkkäinen , Harri Lindholm

Autonomous methods to align beamlines can decrease the amount of time spent on diagnostics, and also uncover better global optima leading to better beam quality. The alignment of these beamlines is a high-dimensional, expensive-to-sample…

In this article, we propose a novel method for sampling potential functions based on noisy observation data of a finite number of observables in quantum canonical ensembles, which leads to the accurate sampling of a wide class of test…

Numerical Analysis · Mathematics 2020-04-08 Ziheng Chen , Zhennan Zhou

Physics-based computer models based on numerical solution of the governing equations generally cannot make rapid predictions, which in turn, limits their applications in the clinic. To address this issue, we developed a physics-informed…

Computational Engineering, Finance, and Science · Computer Science 2024-10-14 Ehsan Naghavi , Haifeng Wang , Lei Fan , Jenny S. Choy , Ghassan Kassab , Seungik Baek , Lik-Chuan Lee

This paper considers the computer model calibration problem and provides a general frequentist solution. Under the proposed framework, the data model is semi-parametric with a nonparametric discrepancy function which accounts for any…

Methodology · Statistics 2015-09-14 Raymond K. W. Wong , Curtis B. Storlie , Thomas C. M. Lee

In the present paper, we derive lower bounds for the risk of the nonparametric empirical Bayes estimators. In order to attain the optimal convergence rate, we propose generalization of the linear empirical Bayes estimation method which…

Statistics Theory · Mathematics 2013-06-12 Rida Benhaddou , Marianna Pensky

Cardiac pulsations in the human brain have received recent interest due to their possible role in the pathogenesis of neurodegenerative diseases. Further interest stems from their possible application as an endogenous signal source that can…

Numerical Analysis · Mathematics 2025-02-06 Lukas Weissinger , Simon Hubmer , Ronny Ramlau , Henning Uwe Voss

Nonclassical correlations provide a resource for many applications in quantum technology as well as providing strong evidence that a system is indeed operating in the quantum regime. Optomechanical systems can be arranged to generate…

The aim of this paper is to put the problem of vibroacoustic imaging into the mathematical framework of inverse problems (more precisely, coefficient identification in PDEs) and regularization. We present a model in frequency domain, prove…

Analysis of PDEs · Mathematics 2021-09-07 Barbara Kaltenbacher

This paper studies the problem of parameter estimation in resonant, acoustic fluid-structure interaction problems over a wide frequency range. Problems with multiple resonances are known to be subjected to local minima, which represents a…

Computational Physics · Physics 2019-03-06 Peter Göransson , Jacques Cuenca , Timo Lähivaara

Parameters in climate models are usually calibrated manually, exploiting only small subsets of the available data. This precludes both optimal calibration and quantification of uncertainties. Traditional Bayesian calibration methods that…

Statistics Theory · Mathematics 2021-10-04 Oliver R. A. Dunbar , Alfredo Garbuno-Inigo , Tapio Schneider , Andrew M. Stuart

Non-invasive assessment of the electrical activation pattern can significantly contribute to the diagnosis and treatment of cardiac arrhythmias, due to faster and safer diagnosis, improved surgical planning and easier follow-up. One…

Medical Physics · Physics 2024-01-09 Nathan Dermul , Hans Dierckx

Data collected by the Interstellar Boundary Explorer (IBEX) satellite, recording heliospheric energetic neutral atoms (ENAs), exhibit a phenomenon that has caused space scientists to revise hypotheses about the physical processes, and…

Inverse parameter estimation of process-based models is a long-standing problem in many scientific disciplines. A key question for inverse parameter estimation is how to define the metric that quantifies how well model predictions fit to…

Populations and Evolution · Quantitative Biology 2014-05-09 Florian Hartig , Claudia Dislich , Thorsten Wiegand , Andreas Huth

This work deals with an inverse two-dimensional nonlinear heat conduction problem to determine the top and lateral surface transfer coefficients. For this, the \textsc{B}ayesian framework with the \textsc{M}arkov Chain \textsc{M}onte…

Computational Engineering, Finance, and Science · Computer Science 2022-06-20 Julien Berger , Clemence Legros

Simulation models for pedestrian crowds are a ubiquitous tool in research and industry. It is crucial that the parameters of these models are calibrated carefully and ultimately it will be of interest to compare competing models to decide…

Multiagent Systems · Computer Science 2020-05-13 Nikolai Bode

Comparing mathematical models offers a means to evaluate competing scientific theories. However, exact methods of model calibration are not applicable to many probabilistic models which simulate high-dimensional spatio-temporal data.…

Quantitative Methods · Quantitative Biology 2026-01-13 Robert A McDonald , Helen M Byrne , Heather A Harrington , Thomas Thorne , Bernadette J Stolz

High precision measurements are essential to solve major scientific and technological challenges, from gravitational wave detection to healthcare diagnostics. Quantum sensing delivers greater precision, but an in-depth optimisation of…