Related papers: Contact-mediated signaling enables disorder-driven…
We give a constructive method for realizing an arbitrary directed graph (with no one-cycles) as a heteroclinic or an excitable dynamic network in the phase space of a system of coupled cells of two types. In each case, the system is…
Signals recorded from neurons with extracellular planar sensors have a wide range of waveforms and amplitudes. This variety is a result of different physical conditions affecting the ion currents through a cellular membrane. The…
Cells in tissues can organize into a broad spectrum of structures according to their function. Drastic changes of organization, such as epithelial-mesenchymal transitions or the formation of spheroidal aggregates, are often associated…
Non-reciprocal interactions play a crucial role in many social and biological complex systems. While directionality has been thoroughly accounted for in networks with pairwise interactions, its effects in systems with higher-order…
Contacts' temporal ordering and dynamics are crucial for understanding the transmission of infectious diseases. We introduce an interaction-driven model of an airborne disease over contact networks. We demonstrate our interaction-driven…
The feedback between mechanical and chemical signals plays a key role in controlling many biological processes and collective cell behavior. Here we focus on the emergence of spatiotemporal density waves in a one-dimensional "cell train."…
Non-genetic heterogeneity is key to cellular decisions, as even genetically identical cells respond in very different ways to the same external stimulus, e.g., during cell differentiation or therapeutic treatment of disease. Strong…
The collective behaviour of confluent cell sheets is strongly influenced both by polar forces, arising through cytoskeletal propulsion and by active inter-cellular forces, which are mediated by interactions across cell-cell junctions. We…
Neuromorphic networks can be described in terms of coarse-grained variables, where emergent sustained behaviours spontaneously arise if stochasticity is properly taken in account. For example it has been recently found that a directed…
We generalize the Cable Model to describe the transport characteristics of the gap junctions coupling adjacent cells in the heart muscle. Our model takes into account recent experimental information about the time dependence of the…
Synchronization of activity among myocytes constituting vital organs, e.g., the heart, is crucial for physiological functions. Self-organized coordination in such heterogeneous ensemble of excitable and oscillatory cells is therefore of…
A fundamental challenge in physics is controlling the propagation of waves in disordered media despite strong scattering from inhomogeneities. Spatial light modulators enable one to synthesize (shape) the incident wavefront, optimizing the…
We analyse the single-mode transmission of microwaves in a guide with internal random structure. The waveguide contains scatterers characterised by random heights and positions, corresponding to compositional and structural disorder. We…
Cellular signaling is essential in information processing and decision making. Therefore, a variety of experimental approaches have been developed to study signaling on bulk and single-cell level. Single-cell measurements of signaling…
Cells collectively migrate as a cluster in three-dimensional (3D) tissues, such as in embryogenesis and cancer invasion. Here, numerical simulations using a 3D vertex model show that polarized interfacial tension, expressing cell adhesion…
Interactions between crawling cells, which are essential for many biological processes, can be quantified by measuring cell-cell collisions. Conventionally, experiments of cell-cell collisions are conducted on two-dimensional flat…
We investigate the dynamic behavior of lattices with disorder introduced through non-local network connections. Inspired by the Watts-Strogatz small-world model, we employ a single parameter to determine the probability of local connections…
We introduce a model of percolation induced by disorder, where an initially homogeneous network with links of equal weight is disordered by the introduction of heterogeneous weights for the links. We consider a pair of nodes i and j to be…
A number of microorganisms leave persistent trails while moving along surfaces. For single-cell organisms, the trail-mediated self-interaction will influence its dynamics. It has been discussed recently [Kranz \textit{et al.} Phys. Rev.…
The dynamics of active matter driven by interacting molecular motors has a non-potential structure at the local scale. However, we show that there exists a quasi-potential effectively describing the collective self-organization of the…