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MRI scans appearance significantly depends on scanning protocols and, consequently, the data-collection institution. These variations between clinical sites result in dramatic drops of CNN segmentation quality on unseen domains. Many of the…

Image and Video Processing · Electrical Eng. & Systems 2020-08-18 Boris Shirokikh , Ivan Zakazov , Alexey Chernyavskiy , Irina Fedulova , Mikhail Belyaev

Medical image registration drives quantitative analysis across organs, modalities, and patient populations. Recent deep learning methods often combine low-level "trend-driven" computational blocks from computer vision, such as large-kernel…

Image and Video Processing · Electrical Eng. & Systems 2025-12-02 Bailiang Jian , Jiazhen Pan , Rohit Jena , Morteza Ghahremani , Hongwei Bran Li , Daniel Rueckert , Christian Wachinger , Benedikt Wiestler

Retinal vessel segmentation serves as a critical prerequisite for automated diagnosis of retinal pathologies. While recent advances in Convolutional Neural Networks (CNNs) have demonstrated promising performance in this task, significant…

Computer Vision and Pattern Recognition · Computer Science 2026-04-03 Zhanqiang Guo , Jianjiang Feng , Jie Zhou

Robustness and generalizability in medical image segmentation are often hindered by scarcity and limited diversity of training data, which stands in contrast to the variability encountered during inference. While conventional strategies --…

Computer Vision and Pattern Recognition · Computer Science 2024-12-18 Yimu Pan , Sitao Zhang , Alison D. Gernand , Jeffery A. Goldstein , James Z. Wang

Segmentation is one of the most important tasks in MRI medical image analysis and is often the first and the most critical step in many clinical applications. In brain MRI analysis, head segmentation is commonly used for measuring and…

Image and Video Processing · Electrical Eng. & Systems 2022-08-11 Haleh Akrami , Wenhui Cui , Anand A Joshi , Richard M. Leahy

Purpose: Different Magnetic resonance imaging (MRI) modalities of the same anatomical structure are required to present different pathological information from the physical level for diagnostic needs. However, it is often difficult to…

Image and Video Processing · Electrical Eng. & Systems 2021-09-15 Yuchen Fei , Bo Zhan , Mei Hong , Xi Wu , Jiliu Zhou , Yan Wang

Automatic segmentation of white matter hyperintensities in magnetic resonance images is of paramount clinical and research importance. Quantification of these lesions serve as a predictor for risk of stroke, dementia and mortality. During…

Image and Video Processing · Electrical Eng. & Systems 2020-09-11 Julian Alberto Palladino , Diego Fernandez Slezak , Enzo Ferrante

Medical image segmentation is vital to the area of medical imaging because it enables professionals to more accurately examine and understand the information offered by different imaging modalities. The technique of splitting a medical…

Image and Video Processing · Electrical Eng. & Systems 2024-09-01 Aitik Gupta , Joydip Dhar

The volume estimation of brain regions from MRI data is a key problem in many clinical applications, where the acquisition of data at high spatial resolution is desirable. While parallel MRI and constrained image reconstruction algorithms…

Image and Video Processing · Electrical Eng. & Systems 2021-05-20 Aniket Pramanik , Xiaodong Wu , Mathews Jacob

This paper presents a comprehensive study focused on disentangling hippocampal shape variations from diffusion tensor imaging (DTI) datasets within the context of neurological disorders. Leveraging a Mesh Variational Autoencoder (VAE)…

Computer Vision and Pattern Recognition · Computer Science 2024-11-12 Jakaria Rabbi , Johannes Kiechle , Christian Beaulieu , Nilanjan Ray , Dana Cobzas

One often lacks sufficient annotated samples for training deep segmentation models. This is in particular the case for less common imaging modalities such as Quantitative Susceptibility Mapping (QSM). It has been shown that deep models tend…

Hippocampus segmentation on magnetic resonance imaging is of key importance for the diagnosis, treatment decision and investigation of neuropsychiatric disorders. Automatic segmentation is an active research field, with many recent models…

Image and Video Processing · Electrical Eng. & Systems 2021-02-12 Diedre Carmo , Bruna Silva , Clarissa Yasuda , Letícia Rittner , Roberto Lotufo

Domain shifts in medical image segmentation, particularly when data comes from different centers, pose significant challenges. Intra-center variability, such as differences in scanner models or imaging protocols, can cause domain shifts as…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jin Hong , Bo Liu

Deep learning holds immense promise for transforming medical image analysis, yet its clinical generalization remains profoundly limited. A major barrier is data heterogeneity. This is particularly true in Magnetic Resonance Imaging, where…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Mehmet Yigit Avci , Pedro Borges , Virginia Fernandez , Paul Wright , Mehmet Yigitsoy , Sebastien Ourselin , Jorge Cardoso

Medical image segmentation is crucial for accurate clinical diagnoses, yet it faces challenges such as low contrast between lesions and normal tissues, unclear boundaries, and high variability across patients. Deep learning has improved…

Image and Video Processing · Electrical Eng. & Systems 2024-12-09 Houze Liu , Tong Zhou , Yanlin Xiang , Aoran Shen , Jiacheng Hu , Junliang Du

Identifying new disease-related patterns in medical imaging data with the help of machine learning enlarges the vocabulary of recognizable findings. This supports diagnostic and prognostic assessment. However, image appearance varies not…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Jeanny Pan , Philipp Seeböck , Christoph Fürböck , Svitlana Pochepnia , Jennifer Straub , Lucian Beer , Helmut Prosch , Georg Langs

Recent advances in deep learning methods have come to define the state-of-the-art for many medical imaging applications, surpassing even human judgment in several tasks. Those models, however, when trained to reduce the empirical risk on a…

Computer Vision and Pattern Recognition · Computer Science 2019-01-14 Christian S. Perone , Pedro Ballester , Rodrigo C. Barros , Julien Cohen-Adad

Semantic segmentation is a critical step in automated image interpretation and analysis where pixels are classified into one or more predefined semantically meaningful classes. Deep learning approaches for semantic segmentation rely on…

Computer Vision and Pattern Recognition · Computer Science 2023-07-10 Tushar Kataria , Beatrice Knudsen , Shireen Elhabian

Domain shift, the mismatch between training and testing data characteristics, causes significant degradation in the predictive performance in multi-source imaging scenarios. In medical imaging, the heterogeneity of population, scanners and…

Machine Learning · Computer Science 2021-12-21 Rongguang Wang , Pratik Chaudhari , Christos Davatzikos

Disentanglement, a critical concern in interpretable machine learning, has also garnered significant attention from the computer vision community. Many existing GAN-based class disentanglement (unsupervised) approaches, such as InfoGAN and…

Computer Vision and Pattern Recognition · Computer Science 2024-06-03 Jiangwei Zhao , Zejia Liu , Xiaohan Guo , Lili Pan