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Time-of-flight (TOF) information provides more accurate location data for annihilation photons, thereby enhancing the quality of PET reconstruction images and reducing noise. List-mode reconstruction has a significant advantage in handling…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Rui Hu , Chenxu Li , Kun Tian , Jianan Cui , Yunmei Chen , Huafeng Liu

Single-bed whole-body positron emission tomography based on resistive plate chamber detectors (RPC-PET) has been proposed for human studies, as a complementary resource to scintillator-based PET scanners. The purpose of this work is mainly…

Uncompressed clinical data from modern positron emission tomography (PET) scanners are very large, exceeding 350 million data points (projection bins). The last decades have seen tremendous advancements in mathematical imaging tools many of…

Medical Physics · Physics 2020-01-08 Matthias J. Ehrhardt , Pawel Markiewicz , Carola-Bibiane Schönlieb

Historically, patient datasets have been used to develop and validate various reconstruction algorithms for PET/MRI and PET/CT. To enable such algorithm development, without the need for acquiring hundreds of patient exams, in this paper we…

PET detectors provide the information of the position, the energy and the timing about the decay events on the LOR. Traditional PET image reconstruction has not taken the timing information into account, only used the timing information for…

Medical Physics · Physics 2020-06-09 Zhenzhou Deng

Small animal PET scanners require high spatial resolution and good sensitivity. To reconstruct high-resolution images in 3D-PET, iterative methods, such as OSEM, are superior to analytical reconstruction algorithms, although their high…

Medical Physics · Physics 2007-05-23 J. L. Herraiz , S. Espana , J. J. Vaquero , M. Desco , J. M. Udias

In this article, we introduce, a novel open-source framework designed for efficient parallel computation of projections in tomography leveraging either multiple CPU cores or GPUs. This framework efficiently implements forward and back…

Medical Physics · Physics 2023-12-18 Georg Schramm , Kris Thielemans

The integration of Time-of-Flight (TOF) information in the reconstruction process of Positron Emission Tomography (PET) yields improved image properties. However, implementing the cutting-edge model-based deep learning methods for TOF-PET…

Image and Video Processing · Electrical Eng. & Systems 2023-02-22 Chenxu Li , Rui Hu , Jianan Cui , Huafeng Liu

Positron Emission Tomography (PET) is an important molecular imaging tool widely used in medicine. Traditional PET systems rely on complete detector rings for full angular coverage and reliable data collection. However, incomplete-ring PET…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Yeqi Fang , Rong Zhou

In recent years, computational Time-of-Flight (ToF) imaging has emerged as an exciting and a novel imaging modality that offers new and powerful interpretations of natural scenes, with applications extending to 3D, light-in-flight, and…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Ruiming Guo , Ayush Bhandari

In positron emission tomography (PET), it is indispensable to perform attenuation correction in order to obtain the quantitatively accurate activity map (tracer distribution) in the body. Generally, this is carried out based on the…

Medical Physics · Physics 2025-10-16 Liyang Hu , Chong Chen

In positron emission tomography (PET), time-of-flight (TOF) information localizes source positions along lines of response. Cherenkov-radiator-integrated microchannel-plate photomultiplier tubes have achieved 30 ps TOF resolution,…

To reconstruct a radioactive tracer distribution with positron emission tomography (PET), the background attenuation correction is needed to eliminate image artifacts. Recent research shows that time-of-flight (TOF) PET data determine the…

Medical Physics · Physics 2013-12-30 Qingsong Yang , Wenxiang Cong , Ge Wang

Spatially and temporally highly resolved depth information enables numerous applications including human-machine interaction in gaming or safety functions in the automotive industry. In this paper, we address this issue using Time-of-flight…

Numerical Analysis · Mathematics 2018-12-27 Stephan Antholzer , Christoph Wolf , Michael Sandbichler , Markus Dielacher , Markus Haltmeier

PET is a functional imaging method that visualizes metabolic processes. TOF information can be derived from coincident detector signals and incorporated into image reconstruction to enhance the SNR. PET detectors are typically assessed by…

Instrumentation and Detectors · Physics 2025-04-24 Stephan Naunheim , Luis Lopes de Paiva , Vanessa Nadig , Yannick Kuhl , Stefan Gundacker , Florian Mueller , Volkmar Schulz

Whole-body PET imaging is often hindered by respiratory motion during acquisition, causing significant degradation in the quality of reconstructed activity images. An additional challenge in PET/CT imaging arises from the respiratory phase…

Intraoperative Gamma Probe (IPG) remains the current gold standard modality for sentinel lymph node identification and tumor removal in cancer patients. However, even alongside the optical dyes they do not meet with <5% false negative rates…

Medical Physics · Physics 2022-01-26 S. Sajedi , L. Blackberg , S. Majewski , H. Sabet

Single-photon lidar has become a prominent tool for depth imaging in recent years. At the core of the technique, the depth of a target is measured by constructing a histogram of time delays between emitted light pulses and detected photon…

Signal Processing · Electrical Eng. & Systems 2022-01-06 Michael P. Sheehan , Julián Tachella , Mike E. Davies

Sparse active illumination enables precise time-of-flight depth sensing as it maximizes signal-to-noise ratio for low power budgets. However, depth completion is required to produce dense depth maps for 3D perception. We address this task…

Computer Vision and Pattern Recognition · Computer Science 2022-05-26 Xiaowen Jiang , Valerio Cambareri , Gianluca Agresti , Cynthia Ifeyinwa Ugwu , Adriano Simonetto , Fabien Cardinaux , Pietro Zanuttigh

We perform a parametric study of the newly developed time-of-flight (TOF) image reconstruction algorithm, proposed for the real-time imaging in total-body Jagiellonian PET (J-PET) scanners. The asymmetric 3D filtering kernel is applied at…

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