Related papers: Molecular Noise In Synaptic Communication
Avalanches with power-law distributed size parameters have been observed in neuronal networks. This observation might be a manifestation of the self-organized criticality (SOC). Yet, the physiological mechanicsm of this behavior is…
Recently Segev et al. (Phys. Rev. E 64,2001, Phys.Rev.Let. 88, 2002) made long-term observations of spontaneous activity of in-vitro cortical networks, which differ from predictions of current models in many features. In this paper we…
Stochasticity is a defining feature of the pairwise forces governing interactions in biological systems-from molecular motors to cell-cell adhesion-yet its consequences on large-scale dynamics remain poorly understood. Here, we show that…
Diffusion Probabilistic Models have demonstrated remarkable performance across a wide range of generative tasks. However, we have observed that these models often suffer from a Signal-to-Noise Ratio-timestep (SNR-t) bias. This bias refers…
Semantic image synthesis (SIS) is a task to generate realistic images corresponding to semantic maps (labels). However, in real-world applications, SIS often encounters noisy user inputs. To address this, we propose Stochastic Conditional…
This paper is devoted to the study of the performance of the Linear Minimum Mean-Square Error receiver for (receive) correlated Multiple-Input Multiple-Output systems. By the random matrix theory, it is well-known that the Signal-to-Noise…
This paper analyses of a stochastic model of a chemical reaction network with three types of chemical species ${\cal R}$, ${\cal M}$ and ${\cal U}$ that interact to transform a flow of external resources, the chemical species ${\cal Q}$, to…
In the mammalian nervous system, various synaptic plasticity rules act, either individually or synergistically, and over wide-ranging timescales to dictate the processes that enable learning and memory formation. To mimic biological…
We introduce a weight update formula that is expressed only in terms of firing rates and their derivatives and that results in changes consistent with those associated with spike-timing dependent plasticity (STDP) rules and biological…
In this paper, we consider a diffusive mobile molecular communication (MC) system consisting of a pair of mobile transmitter and receiver nano-machines suspended in a fluid medium, where we model the mobility of the nano-machines by…
Serotonergic neurons of the dorsal raphe nuclei, with their extensive innervation of nearly the whole brain have important modulatory effects on many cognitive and physiological processes. They play important roles in clinical depression…
An increasing body of evidence suggests that the trial-to-trial variability of spiking activity in the brain is not mere noise, but rather the reflection of a sampling-based encoding scheme for probabilistic computing. Since the precise…
We propose a novel discrete model of central pattern generators (CPG), neuronal ensembles generating rhythmic activity. The model emphasizes the role of nonsynaptic interactions and the diversity of electrical properties in nervous systems.…
Epilepsy is a neurological disorder with recurrent seizures of complexity and randomness. Until now, the mechanism of epileptic randomness has not been fully elucidated. Inspired by the recent finding that astrocyte GTPase-activating…
Neurons in the central nervous system are affected by complex and noisy signals due to fluctuations in their cellular environment and in the inputs they receive from many other cells 1,2. Such noise usually increases the probability that a…
Conventional analysis of neuroscience data involves computing average neural activity over a group of trials and/or a period of time. This approach may be particularly problematic when assessing the response patterns of neurons to more than…
In this paper, we develop a mathematical framework for modeling the time-variant stochastic channels of diffusive mobile MC systems. In particular, we consider a diffusive mobile MC system consisting of a pair of transmitter and receiver…
We consider a sequential cascade of molecular first-reaction events towards a terminal reaction centre in which each reaction step is controlled by diffusive motion of the particles. The model studied here represents a typical reaction…
Statistical modal Energy distribution Analysis (SmEdA) can be used as an alternative to Statistical Energy Analysis for describing subsystems with low modal overlap. In its original form, SmEdA predicts the power flow exchanged between the…
Recently, hybrid models have emerged that combine microscopic and mesoscopic regimes in a single stochastic reaction-diffusion simulation. Microscopic simulations track every individual molecule and are generally more accurate. Mesoscopic…