English
Related papers

Related papers: Curvature effects in charge-regulated lipid bilaye…

200 papers

Plasma membranes appear as deformable systems wherein molecules are free to move and diffuse giving rise to condensed microdomains (composed of ordered lipids, transmembrane proteins and cholesterol) surrounded by disordered lipid…

Soft Condensed Matter · Physics 2024-09-25 Chiara Bernard , Angelo Rosario Carotenuto , Nicola Maria Pugno , Luca Deseri , Massimiliano Fraldi

In this paper the problem of surface charge of the lipid membrane immersed in the physiological solution is considered. It is shown that both side of the bilayer phospholipid membrane surface are negatively charged. A self-consistent model…

Biological Physics · Physics 2015-05-14 M. Pekker , M. N. Shneider

We investigate a model of an asymmetric bilayer consisting of sphigomyelin, phosphatidylcholine, and cholesterol in the outer leaflet, and phosphatidyl\-ethanolamine, (PE), phosphatidylserine, and cholesterol in the inner leaflet.…

Soft Condensed Matter · Physics 2016-08-23 H. Giang , M. Schick

Linear sweep and cyclic voltammetry techniques are important tools for electrochemists and have a variety of applications in engineering. Voltammetry has classically been treated with the Randles-Sevcik equation, which assumes an…

Chemical Physics · Physics 2017-03-15 David Yan , Martin Z. Bazant , P. M. Biesheuvel , Mary C. Pugh , Francis P. Dawson

Experiments on supported lipid bilayers featuring liquid ordered/disordered domains have shown that the spatial arrangement of the lipid domains and their chemical composition are strongly affected by the curvature of the substrate.…

Soft Condensed Matter · Physics 2021-02-17 Melissa Rinaldin , Piermarco Fonda , Luca Giomi , Daniela J. Kraft

We present a simple and computationally efficient coarse-grained and solvent-free model for simulating lipid bilayer membranes. In order to be used in concert with particle-based reaction-diffusion simulations, the model is purely based on…

Biological Physics · Physics 2018-01-31 Mohsen Sadeghi , Thomas R. Weikl , Frank Noé

We discuss the dynamics of a bilayer membrane with partial slip boundary conditions between the monolayers and the bulk fluid. Using Onsager's variational principle to account for the associated dissipations, we derive the coupled dynamic…

Soft Condensed Matter · Physics 2018-07-18 Kento Yasuda , Ryuichi Okamoto , Shigeyuki Komura , Jean-Baptiste Fournier

The interplay of membrane proteins is vital for many biological processes, such as cellular transport, cell division, and signal transduction between nerve cells. Theoretical considerations have led to the idea that the membrane itself…

Soft Condensed Matter · Physics 2016-11-28 Casper van der Wel , Afshin Vahid , Anđela Šarić , Timon Idema , Doris Heinrich , Daniela J. Kraft

Monolayer spontaneous curvatures for cholesterol, DOPE, POPE, DOPC, DPPC, DSPC, POPC, SOPC, and egg sphingomyelin were obtained using small-angle X-ray scattering (SAXS) on inverted hexagonal phases (HII). Spontaneous curvatures of bilayer…

Soft Condensed Matter · Physics 2013-10-08 Benjamin Kollmitzer , Peter Heftberger , Michael Rappolt , Georg Pabst

We study the problem of charge regulation and its effects on electrostatic interactions between dissociable charge groups immersed in a univalent electrolyte, within a family of one dimensional exactly solvable models. We consider the case…

Soft Condensed Matter · Physics 2015-06-23 A. C. Maggs , R. Podgornik

Common models for two-phase lipid bilayer membranes are based on an energy that consists of an elastic term for each lipid phase and a line energy at interfaces. Although such an energy controls only the length of interfaces, the membrane…

Analysis of PDEs · Mathematics 2016-03-10 Michael Helmers

We report a new and facile method for measuring edge tensions of lipid membranes. The approach is based on electroporation of giant unilamellar vesicles and analysis of the pore closure dynamics. We applied this method to evaluate the edge…

Biological Physics · Physics 2011-02-11 Thomas Portet , Rumiana Dimova

Charge regulation is an important aspect of electrostatics in biological and colloidal systems, where the charges are generally not fixed, but depend on the environmental variables. Here, we analyze the charge regulation mechanism in…

Soft Condensed Matter · Physics 2018-08-01 Anže Lošdorfer Božič , Rudolf Podgornik

The study of interactions between biomimetic membranes and micron-sized particles is crucial for understanding various biological processes. Here, we control microparticle spontaneous engulfment by giant lipid vesicles by tuning particle…

Soft Condensed Matter · Physics 2025-01-22 Clément Marque , Gaetano D'Avino , Domenico Larobina , Aude Michel , Ali Abou-Hassan , Antonio Stocco

Onsager's variational principle is generalized to address the diffusive dynamics of an electrolyte solution composed of charge-regulated macro-ions and counterions. The free energy entering the Rayleighian corresponds to the…

Soft Condensed Matter · Physics 2025-05-26 Bin Zheng , Shigeyuki Komura , David Andelman , Rudolf Podgornik

We investigate the interaction between highly charged lipid bilayers in the presence of monovalent counterions. Neutron and X-ray reflectivity experiments show that the water layer between like-charged bilayers is thinner than for…

We study membrane-protein interactions and membrane-mediated protein-protein interactions by Monte Carlo simulations of a generic coarse-grained model for lipid bilayers with cylindrical hydrophobic inclusions. The strength of the…

Biological Physics · Physics 2009-11-13 Beate West , Frank L. H. Brown , Friederike Schmid

Cholesterol plays an essential role in biological membranes and is crucial for maintaining their stability and functionality. It is necessary for a variety of membranes, including planar bilayers, liposomes, curved bilayers, nanodiscs, and…

Biomolecules · Quantitative Biology 2025-04-09 Ehsaneh Khodadadi , Ehsan Khodadadi , Parth Chaturvedi , Mahmoud Moradi

We employ 100 ns molecular dynamics simulations to study the influence of cholesterol on structural and dynamic properties of dipalmitoylphosphatidylcholine (DPPC) bilayers in the fluid phase. The effects of the cholesterol content on the…

Soft Condensed Matter · Physics 2009-11-10 Emma Falck , Michael Patra , Mikko Karttunen , Marja T. Hyvonen , Ilpo Vattulainen

On the basis of a hydrodynamical model analogous to that in critical fluids, we investigate the influences of shear flow upon the electrostatic contribution to the viscosity of binary electrolyte solutions in the Debye-H\"{u}ckel…

Statistical Mechanics · Physics 2007-05-23 Hirofumi Wada