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Alzheimer's disease and Frontotemporal dementia are common forms of neurodegenerative dementia. Behavioral alterations and cognitive impairments are found in the clinical courses of both diseases and their differential diagnosis is…

Image and Video Processing · Electrical Eng. & Systems 2023-09-12 Huy-Dung Nguyen , Michaël Clément , Vincent Planche , Boris Mansencal , Pierrick Coupé

The recent boom of large language models (LLMs) has re-ignited the hope that artificial intelligence (AI) systems could aid medical diagnosis. Yet despite dazzling benchmark scores, LLM assistants have yet to deliver measurable improvements…

Artificial Intelligence · Computer Science 2025-07-03 Matthew JY Kang , Wenli Yang , Monica R Roberts , Byeong Ho Kang , Charles B Malpas

In this study, we employ a transformer encoder model to characterize the significance of longitudinal patient data for forecasting the progression of Alzheimer's Disease (AD). Our model, Longitudinal Forecasting Model for Alzheimer's…

Machine Learning · Computer Science 2024-05-28 Batuhan K. Karaman , Mert R. Sabuncu

Missing data theory deals with the statistical methods in the occurrence of missing data. Missing data occurs when some values are not stored or observed for variables of interest. However, most of the statistical theory assumes that data…

Data-driven method for Structural Health Monitoring (SHM), that mine the hidden structural performance from the correlations among monitored time series data, has received widely concerns recently. However, missing data significantly…

Machine Learning · Computer Science 2023-04-04 Fan Deng , Xiaoming Tao , Pengxiang Wei , Shiyin Wei

Alzheimer's disease and Frontotemporal dementia are two major types of dementia. Their accurate diagnosis and differentiation is crucial for determining specific intervention and treatment. However, differential diagnosis of these two types…

Image and Video Processing · Electrical Eng. & Systems 2022-06-16 Huy-Dung Nguyen , Michaël Clément , Boris Mansencal , Pierrick Coupé

We present a method for incorporating missing data in non-parametric statistical learning without the need for imputation. We focus on a tree-based method, Bayesian Additive Regression Trees (BART), enhanced with "Missingness Incorporated…

Machine Learning · Statistics 2014-02-14 Adam Kapelner , Justin Bleich

An interpretable machine learning (ML) framework is introduced to enhance the diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD) by ensuring robustness of the ML models' interpretations. The dataset used comprises…

Despite much research targeted at enabling conventional machine learning models to continually learn tasks and data distributions sequentially without forgetting the knowledge acquired, little effort has been devoted to account for more…

Machine Learning · Computer Science 2021-06-11 Sandra Servia-Rodriguez , Cecilia Mascolo , Young D. Kwon

Alzheimer's disease (AD) is a prevalent neurodegenerative disorder that progressively impairs memory, decision-making, and overall cognitive function. As AD is irreversible, early prediction is critical for timely intervention and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Mahdieh Behjat Khatooni , Mohsen Soryani

Handling missing data in time series classification remains a significant challenge in various domains. Traditional methods often rely on imputation, which may introduce bias or fail to capture the underlying temporal dynamics. In this…

Machine Learning · Computer Science 2026-04-03 YongKyung Oh , Dong-Young Lim , Sungil Kim , Alex Bui

Alzheimer's disease (AD) is a progressive brain disorder that causes memory and functional impairments. The advances in machine learning and publicly available medical datasets initiated multiple studies in AD diagnosis. In this work, we…

Image and Video Processing · Electrical Eng. & Systems 2021-07-20 Aidana Massalimova , Huseyin Atakan Varol

This paper is a submission to the Alzheimer's Dementia Recognition through Spontaneous Speech (ADReSS) challenge, which aims to develop methods that can assist in the automated prediction of severity of Alzheimer's Disease from speech data.…

Machine Learning · Computer Science 2021-06-18 Morteza Rohanian , Julian Hough , Matthew Purver

Missing data in time series is a pervasive problem that puts obstacles in the way of advanced analysis. A popular solution is imputation, where the fundamental challenge is to determine what values should be filled in. This paper proposes…

Machine Learning · Computer Science 2023-07-06 Wenjie Du , David Cote , Yan Liu

Learning from multimodal datasets can leverage complementary information and improve performance in prediction tasks. A commonly used strategy to account for feature correlations in high-dimensional datasets is the latent variable approach.…

Machine Learning · Computer Science 2024-10-01 Lingchao Mao , Qi wang , Yi Su , Fleming Lure , Jing Li

For multi-source data, blocks of variable information from certain sources are likely missing. Existing methods for handling missing data do not take structures of block-wise missing data into consideration. In this paper, we propose a…

Methodology · Statistics 2020-04-07 Fei Xue , Annie Qu

We describe the Bedside Patient Rescue (BPR) project, the goal of which is risk prediction of adverse events for non-ICU patients using ~200 variables (vitals, lab results, assessments, ...). There are several missing predictor values for…

In this work, we consider the problem of predicting the course of a progressive disease, such as cancer or Alzheimer's. Progressive diseases often start with mild symptoms that might precede a diagnosis, and each patient follows their own…

Machine Learning · Computer Science 2018-03-19 Yingying Zhu , Mert R. Sabuncu

Purpose: The primary goal of this study is to explore the application of evaluation metrics to different clustering algorithms using the data provided from the Canadian Longitudinal Study (CLSA), focusing on cognitive features. The…

Machine Learning · Computer Science 2025-05-19 ChenNingZhi Sheng

As a general and robust alternative to traditional mean regression models, quantile regression avoids the assumption of normally distributed errors, making it a versatile choice when modeling outcomes such as cognitive scores that typically…

Methodology · Statistics 2026-03-19 Rongke Lyu , Marina Vannucci , Suprateek Kundu