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Whole slide images (WSIs) are vital in digital pathology, enabling gigapixel tissue analysis across various pathological tasks. While recent advancements in multi-modal large language models (MLLMs) allow multi-task WSI analysis through…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Xinheng Lyu , Yuci Liang , Wenting Chen , Meidan Ding , Jiaqi Yang , Guolin Huang , Daokun Zhang , Xiangjian He , Linlin Shen

Whole-slide image (WSI) classification in computational pathology is commonly formulated as slide-level Multiple Instance Learning (MIL) with a single global bag representation. However, slide-level MIL is fundamentally underconstrained:…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Syed Fahim Ahmed , Gnanesh Rasineni , Florian Koehler , Abu Zahid Bin Aziz , Mei Wang , Attila Gyulassy , Brian Summa , J. Quincy Brown , Valerio Pascucci , Shireen Y. Elhabian

Multi-channel Analysis of Surface Waves (MASW) is a seismic method employed to obtain useful information about shear-wave velocities in the near surface. A fundamental step in this methodology is the extraction of dispersion curves from…

Accurate and reliable Magnetic Resonance Imaging (MRI) analysis is particularly important for adaptive radiotherapy, a recent medical advance capable of improving cancer diagnosis and treatment. Recent studies have shown that IVIM-NET, a…

Hardware Architecture · Computer Science 2024-07-09 Zehuan Zhang , Matej Genci , Hongxiang Fan , Andreas Wetscherek , Wayne Luk

The maximum likelihood estimation is computationally demanding for large datasets, particularly when the likelihood function includes integrals. Subsampling can reduce the computational burden, but it often results in efficiency loss.This…

Methodology · Statistics 2026-04-27 Miaomiao Su , Qihua Wang , Ruoyu Wang

Sparse-view satellite image surface reconstruction remains highly challenging, fundamentally because the reliability of multi-view matching under satellite imaging conditions is strongly spatially heterogeneous. Affected by large…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Min Chen , Wei Guo , Bin Wang , Wen Li , Tong Fang , Jinbo Zhang , Junqi Zhao , Hong Kuang , Han Hu , Xuming Ge , Qing Zhu , Bo Xu

Multiple instance learning (MIL) has been increasingly used in the classification of histopathology whole slide images (WSIs). However, MIL approaches for this specific classification problem still face unique challenges, particularly those…

Computer Vision and Pattern Recognition · Computer Science 2022-03-24 Hongrun Zhang , Yanda Meng , Yitian Zhao , Yihong Qiao , Xiaoyun Yang , Sarah E. Coupland , Yalin Zheng

Whole-slide images are central to digital pathology, yet their extreme size and scarce annotations make self-supervised learning essential. Masked Autoencoders (MAEs) with Vision Transformer backbones have recently shown strong potential…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Raneen Younis , Louay Hamdi , Lukas Chavez , Zahra Ahmadi

Introduction: Nottingham grading system is a major prognostic factor for invasive breast carcinoma (IBC). Its determination requires the evaluation of the mitotic score (MS) which is subject to low intra- and inter-observer reproducibility.…

Survival prediction, utilizing pathological images and genomic profiles, is increasingly important in cancer analysis and prognosis. Despite significant progress, precise survival analysis still faces two main challenges: (1) The massive…

Image and Video Processing · Electrical Eng. & Systems 2024-06-26 Songhan Jiang , Zhengyu Gan , Linghan Cai , Yifeng Wang , Yongbing Zhang

Attention-based multiple instance learning (AMIL) algorithms have proven to be successful in utilizing gigapixel whole-slide images (WSIs) for a variety of different computational pathology tasks such as outcome prediction and cancer…

Masked autoencoders (MAEs) have displayed significant potential in the classification and semantic segmentation of medical images in the last year. Due to the high similarity of human tissues, even slight changes in medical images may…

Computer Vision and Pattern Recognition · Computer Science 2023-05-11 Jiawei Mao , Shujian Guo , Yuanqi Chang , Xuesong Yin , Binling Nie

Sparse inverse covariance estimation (i.e., edge de-tection) is an important research problem in recent years, wherethe goal is to discover the direct connections between a set ofnodes in a networked system based upon the observed…

Machine Learning · Computer Science 2021-01-15 Hang Yin , Xinyue Liu , Xiangnan Kong

Whole-Slide Images (WSIs) are widely used for estimating the prognosis of cancer patients. Current studies generally follow a cancer-specific learning paradigm. However, the available training samples for one cancer type are usually scarce…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Pei Liu , Xiangxiang Zeng , Tengfei Ma , Yucheng Xing , Xuanbai Ren , Yiping Liu

Single image super-resolution (SISR) aims to obtain a high-resolution output from one low-resolution image. Currently, deep learning-based SISR approaches have been widely discussed in medical image processing, because of their potential to…

Image and Video Processing · Electrical Eng. & Systems 2021-05-25 Jin Zhu , Chuan Tan , Junwei Yang , Guang Yang , Pietro Lio'

Acquiring pixel-level annotations is often limited in applications such as histology studies that require domain expertise. Various semi-supervised learning approaches have been developed to work with limited ground truth annotations, such…

Computer Vision and Pattern Recognition · Computer Science 2024-03-20 Qiangguo Jin , Hui Cui , Changming Sun , Yang Song , Jiangbin Zheng , Leilei Cao , Leyi Wei , Ran Su

Accurate tumor detection in digital pathology whole-slide images (WSIs) is crucial for cancer diagnosis and treatment planning. Multiple Instance Learning (MIL) has emerged as a widely used approach for weakly-supervised tumor detection…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Marina D'Amato , Jeroen van der Laak , Francesco Ciompi

The use of wearable technology for posture monitoring has been expanding due to its low-intrusiveness and compliance with daily use requirements. However, there are still open challenges limiting its widespread use, especially when dealing…

Human-Computer Interaction · Computer Science 2022-02-16 Manuel Palermo , Sara Cerqueira , João André , António Pereira , Cristina P. Santos

The Segment Anything Model (SAM) marks a significant advancement in segmentation models, offering robust zero-shot abilities and dynamic prompting. However, existing medical SAMs are not suitable for the multi-scale nature of whole-slide…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Hong Liu , Haosen Yang , Paul J. van Diest , Josien P. W. Pluim , Mitko Veta

The deep neural network is a research hotspot for histopathological image analysis, which can improve the efficiency and accuracy of diagnosis for pathologists or be used for disease screening. The whole slide pathological image can reach…

Image and Video Processing · Electrical Eng. & Systems 2022-05-09 Tingting Zheng , Weixing chen , Shuqin Li , Hao Quan , Qun Bai , Tianhang Nan , Song Zheng , Xinghua Gao , Yue Zhao , Xiaoyu Cui
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