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This paper proposes a data-driven model for solving the inverse problem of electrocardiography, the mathematical problem that forms the basis of electrocardiographic imaging (ECGI). We present a conditional diffusion framework that learns a…

Machine Learning · Computer Science 2026-01-27 Ramiro Valdes Jara , Adam Meyers

Computational modelling offers a cost-effective and time-efficient alternative to experimental studies in biomedical engineering. In cardiac electro-mechanics, finite element method (FEM)-based simulations provide valuable insights into…

Computational Engineering, Finance, and Science · Computer Science 2025-08-20 Tan Tran , Denisa Martonova , Sigrid Leyendecker

A thermodynamically consistent phase-field model is introduced for simulating motion and shape transformation of vesicles under flow conditions. In particular, a general slip boundary condition is used to describe the interaction between…

Numerical Analysis · Mathematics 2020-12-11 Lingyue Shen , Zhiliang Xu , Ping Lin , Huaxiong Huang , Shixin Xu

In the process of patient diagnosis, non-invasive measurements are widely used due to their low risks and quick results. Electrocardiogram (ECG), as a non-invasive method to collect heart activities, is used to diagnose cardiac conditions.…

Machine Learning · Computer Science 2025-12-11 Yuhao Xu , Jiaying Lu , Sirui Ding , Defu Cao , Xiao Hu , Carl Yang

Imbalanced electrocardiogram (ECG) data hampers the efficacy and resilience of algorithms in the automated processing and interpretation of cardiovascular diagnostic information, which in turn impedes deep learning-based ECG classification.…

Machine Learning · Computer Science 2026-01-15 Haijian Shao , Wei Liu , Xing Deng , Daze Lu

This paper presents a computational solution that enables continuous cardiac monitoring through cross-modality inference of electrocardiogram (ECG). While some smartwatches now allow users to obtain a 30-second ECG test by tapping a…

Signal Processing · Electrical Eng. & Systems 2024-05-20 Yuenan Li , Xin Tian , Qiang Zhu , Min Wu

This study proposes an end-to-end unsupervised diffeomorphic deformable registration framework based on moving mesh parameterization. Using this parameterization, a deformation field can be modeled with its transformation Jacobian…

Image and Video Processing · Electrical Eng. & Systems 2022-08-30 Ameneh Sheikhjafari , Deepa Krishnaswamy , Michelle Noga , Nilanjan Ray , Kumaradevan Punithakumar

The electrocardiogram (ECG) is one of the most common primary tests to evaluate the health of the heart. Reliable automatic interpretation of ECG records is crucial to the goal of improving public health. It can enable a safe inexpensive…

Signal Processing · Electrical Eng. & Systems 2023-01-18 Laura Rebollo-Neira , Khalil Battikh , Amadou Sidi Watt

The complex dynamics of the heart are reflected in its electrical activity, captured through electrocardiograms (ECGs). In this study we use nonlinear time series analysis to understand how ECG complexity varies with cardiac pathology.…

Signal Processing · Electrical Eng. & Systems 2025-10-22 Camilo Quiceno Quintero , Sandip Varkey George

Liposomes that achieve a heterogeneous and spatially organized surface through phase separation have been recognized to be a promising platform for delivery purposes. However, their design and optimization through experimentation can be…

Soft Condensed Matter · Physics 2021-11-05 Y. Wang , Y. Palzhanov , A. Quaini , M. Olshanskii , S. Majd

This review focuses on the computerized modeling of the electrophysiology of the human atria, emphasizing the simulation of common arrhythmias such as atrial flutter (AFlut) and atrial fibrillation (AFib). Which components of the model are…

Computational Physics · Physics 2025-05-30 Olaf Dössel , Axel Loewe

Noninvasive reconstruction of cardiac electrical activity from surface electrocardiograms (ECG) involves solving an ill-posed inverse problem. Cardiac electrophysiological (EP) models have been used as important a priori knowledge to…

Image and Video Processing · Electrical Eng. & Systems 2019-05-14 Sandesh Ghimire , John L Sapp , Milan Horacek , Linwei Wang

Parameter estimation and uncertainty quantification are crucial in computational cardiology, as they enable the construction of digital twins that faithfully replicate the behavior of physical patients. Robust and efficient mathematical…

Numerical Analysis · Mathematics 2022-10-07 Matteo Salvador , Francesco Regazzoni , Luca Dede' , Alfio Quarteroni

The efficient construction of anatomical models is one of the major challenges of patient-specific in-silico models of the human heart. Current methods frequently rely on linear statistical models, allowing no advanced topological changes,…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Jan Verhülsdonk , Thomas Grandits , Francisco Sahli Costabal , Thomas Pinetz , Rolf Krause , Angelo Auricchio , Gundolf Haase , Simone Pezzuto , Alexander Effland

The accelerating trend of active metasurfaces -- such as those incorporating non-Foster matching, programmable control, or space-time modulation -- adds complexity to the computational electromagnetic (CEM) simulation landscape. In this…

Applied Physics · Physics 2024-12-10 Christopher T. Howard , William D. Hunt , Kenneth W. Allen

In this work we search for best practices in pre-processing of Electrocardiogram (ECG) signals in order to train better classifiers for the diagnosis of heart conditions. State of the art machine learning algorithms have achieved remarkable…

Signal Processing · Electrical Eng. & Systems 2025-05-16 Amir Salimi , Sunil Vasu Kalmady , Abram Hindle , Osmar Zaiane , Padma Kaul

The inverse mechano-electrical problem in cardiac electrophysiology is the attempt to reconstruct electrical excitation or action potential wave patterns from the heart's mechanical deformation that occurs in response to electrical…

Image and Video Processing · Electrical Eng. & Systems 2021-11-10 Jan Christoph , Jan Lebert

Modern wearable devices are embedded with a range of noninvasive biomarker sensors that hold promise for improving detection and treatment of disease. One such sensor is the single-lead electrocardiogram (ECG) which measures electrical…

Machine Learning · Statistics 2020-12-02 Jeffrey Chan , Andrew C. Miller , Emily B. Fox

Synthetic electrocardiogram generation serves medical AI applications requiring privacy-preserving data sharing and training dataset augmentation. Current diffusion-based methods achieve high generation quality but require hundreds of…

Signal Processing · Electrical Eng. & Systems 2025-09-16 Vitalii Bondar , Serhii Semenov , Vira Babenko , Dmytro Holovniak

Electrocardiogram (ECG)-based models have achieved strong performance in diagnostic tasks, yet they remain limited in modeling how cardiac dynamics evolve under external interventions. In particular, existing approaches focus primarily on…

Artificial Intelligence · Computer Science 2026-05-19 Zhikang Chen , Yue Wang , Sen Cui , Yu Zhang , Changshui Zhang , Tianling Ren , Tingting Zhu
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