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Multiplexed imaging data are revolutionizing our understanding of the composition and organization of tissues and tumors. A critical aspect of such tissue profiling is quantifying the spatial relationship relationships among cells at…

Quantitative Methods · Quantitative Biology 2024-05-06 Ajit J. Nirmal , Peter K. Sorger

Projections, or dimensionality reduction methods, are techniques of choice for the visual exploration of high-dimensional data. Many such techniques exist, each one of them having a distinct visual signature - i.e., a recognizable way to…

Human-Computer Interaction · Computer Science 2026-02-25 Alister Machado , Alexandru Telea , Michael Behrisch

Supervised mapping methods project multi-dimensional labeled data onto a 2-dimensional space attempting to preserve both data similarities and topology of classes. Supervised mappings are expected to help the user to understand the…

Information Retrieval · Computer Science 2012-03-12 Sylvain Lespinats , Anke Meyer-Baese , Michael Aupetit

Supervised manifold learning methods learn data representations by preserving the geometric structure of data while enhancing the separation between data samples from different classes. In this work, we propose a theoretical study of…

Machine Learning · Computer Science 2018-01-08 Elif Vural , Christine Guillemot

We present an approach to explain the decisions of black box models for image classification. While using the black box to label images, our explanation method exploits the latent feature space learned through an adversarial autoencoder.…

Computer Vision and Pattern Recognition · Computer Science 2020-02-11 Riccardo Guidotti , Anna Monreale , Stan Matwin , Dino Pedreschi

Explainable Artificial Intelligence (XAI) has in recent years become a well-suited framework to generate human understandable explanations of "black-box" models. In this paper, a novel XAI visual explanation algorithm known as the…

Computer Vision and Pattern Recognition · Computer Science 2022-07-12 Satya M. Muddamsetty , Mohammad N. S. Jahromi , Andreea E. Ciontos , Laura M. Fenoy , Thomas B. Moeslund

Manifold learning approaches seek the intrinsic, low-dimensional data structure within a high-dimensional space. Mainstream manifold learning algorithms, such as Isomap, UMAP, $t$-SNE, Diffusion Map, and Laplacian Eigenmaps do not use data…

Machine Learning · Statistics 2023-07-04 Jake S. Rhodes

The increased interest in deep learning applications, and their hard-to-detect biases result in the need to validate and explain complex models. However, current explanation methods are limited as far as both the explanation of the…

Computer Vision and Pattern Recognition · Computer Science 2023-01-05 Weronika Hryniewska , Adrianna Grudzień , Przemysław Biecek

As machine learning black boxes are increasingly being deployed in domains such as healthcare and criminal justice, there is growing emphasis on building tools and techniques for explaining these black boxes in an interpretable manner. Such…

Machine Learning · Computer Science 2020-02-04 Dylan Slack , Sophie Hilgard , Emily Jia , Sameer Singh , Himabindu Lakkaraju

Despite outstanding contribution to the significant progress of Artificial Intelligence (AI), deep learning models remain mostly black boxes, which are extremely weak in explainability of the reasoning process and prediction results.…

Machine Learning · Computer Science 2020-02-11 Sheng Shi , Xinfeng Zhang , Wei Fan

Projections (or dimensionality reduction) methods $P$ aim to map high-dimensional data to typically 2D scatterplots for visual exploration. Inverse projection methods $P^{-1}$ aim to map this 2D space to the data space to support tasks such…

Human-Computer Interaction · Computer Science 2026-02-12 Yu Wang , Frederik L. Dennig , Michael Behrisch , Alexandru Telea

Scientific and engineering processes deliver massive high-dimensional data sets that are generated as non-linear transformations of an initial state and few process parameters. Mapping such data to a low-dimensional manifold facilitates…

Machine Learning · Statistics 2018-08-07 Frank Schoeneman , Varun Chandola , Nils Napp , Olga Wodo , Jaroslaw Zola

With the advancement of technology for artificial intelligence (AI) based solutions and analytics compute engines, machine learning (ML) models are getting more complex day by day. Most of these models are generally used as a black box…

Machine Learning · Computer Science 2022-10-11 P. Sai Ram Aditya , Mayukha Pal

We present a new technique for visualizing high-dimensional data called cluster MDS (cl-MDS), which addresses a common difficulty of dimensionality reduction methods: preserving both local and global structures of the original sample in a…

Graphics · Computer Science 2024-05-27 Patricia Hernández-León , Miguel A. Caro

In an era where black-box AI models are integral to decision-making across industries, robust methods for explaining these models are more critical than ever. While these models leverage complex feature interplay for accurate predictions,…

Human-Computer Interaction · Computer Science 2025-03-24 Anna Kleinau , Bernhard Preim , Monique Meuschke

Supervised Machine Learning (SML) algorithms such as Gradient Boosting, Random Forest, and Neural Networks have become popular in recent years due to their increased predictive performance over traditional statistical methods. This is…

Machine Learning · Statistics 2018-06-05 Linwei Hu , Jie Chen , Vijayan N. Nair , Agus Sudjianto

A fundamental problem in supervised learning is to find a good set of features or distance measures. If the new set of features is of lower dimensionality and can be obtained by a simple transformation of the original data, they can make…

Machine Learning · Computer Science 2024-05-15 Anri Patron , Ayush Prasad , Hoang Phuc Hau Luu , Kai Puolamäki

Owing to the advances in computational techniques and the increase in computational power, atomistic simulations of materials can simulate large systems with higher accuracy. Complex phenomena can be observed in such state-of-the-art…

Materials Science · Physics 2022-02-16 Ryo Tamura , Momo Matsuda , Jianbo Lin , Yasunori Futamura , Tetsuya Sakurai , Tsuyoshi Miyazaki

Existing works on "black-box" model interpretation use local-linear approximations to explain the predictions made for each data instance in terms of the importance assigned to the different features for arriving at the prediction. These…

Machine Learning · Computer Science 2019-08-28 Kartik Ahuja , William Zame , Mihaela van der Schaar

Vision-language foundation models such as CLIP have achieved tremendous results in global vision-language alignment, but still show some limitations in creating representations for specific image regions. % To address this problem, we…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Walid Bousselham , Sofian Chaybouti , Christian Rupprecht , Vittorio Ferrari , Hilde Kuehne