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A fully automated knee MRI segmentation method to study osteoarthritis (OA) was developed using a novel hierarchical set of random forests (RF) classifiers to learn the appearance of cartilage regions and their boundaries. A neighborhood…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Satyananda Kashyap , Honghai Zhang , Karan Rao , Milan Sonka

Degeneration of articular cartilage (AC) is actively studied in knee osteoarthritis (OA) research via magnetic resonance imaging (MRI). Segmentation of AC tissues from MRI data is an essential step in quantification of their damage. Deep…

Image and Video Processing · Electrical Eng. & Systems 2024-08-07 Egor Panfilov , Aleksei Tiulpin , Stefan Klein , Miika T. Nieminen , Simo Saarakkala

Convolutional neural networks (CNNs) have gained significant popularity in orthopedic imaging in recent years due to their ability to solve fracture classification problems. A common criticism of CNNs is their opaque learning and reasoning…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Zhibin Liao , Kewen Liao , Haifeng Shen , Marouska F. van Boxel , Jasper Prijs , Ruurd L. Jaarsma , Job N. Doornberg , Anton van den Hengel , Johan W. Verjans

Radiographic grading of knee osteoarthritis (KOA) with the Kellgren-Lawrence (KL) system is limited by inter-reader variability and the opacity of current deep learning approaches, which predict KL grades directly from images without…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Azmul A. Irfan , Nur Ahmad Khatim , Alfan Alfian Irfan , Achmad Zaki , Erike A. Suwarsono , Mansur M. Arief

Precise segmentation of knee tissues from magnetic resonance imaging (MRI) is critical in quantitative imaging and diagnosis. Convolutional neural networks (CNNs), which are state of the art, have limitations owing to the lack of…

Image and Video Processing · Electrical Eng. & Systems 2021-09-30 Sheheryar Khan , Basim Azam , Yongcheng Yao , Weitian Chen

The development of machine learning systems for the diagnosis of rare diseases is challenging mainly due the lack of data to study them. Despite this challenge, this paper proposes a system for the Computer Aided Diagnosis (CAD) of…

Computer Vision and Pattern Recognition · Computer Science 2019-02-01 Adrián Bazaga , Mònica Roldán , Carmen Badosa , Cecilia Jiménez-Mallebrera , Josep M. Porta

The severity of knee osteoarthritis is graded using the 5-point Kellgren-Lawrence (KL) scale where healthy knees are assigned grade 0, and the subsequent grades 1-4 represent increasing severity of the affliction. Although several methods…

Image and Video Processing · Electrical Eng. & Systems 2020-04-21 Sudeep Kondal , Viraj Kulkarni , Ashrika Gaikwad , Amit Kharat , Aniruddha Pant

The 3D morphology and quantitative assessment of knee articular cartilages (i.e., femoral, tibial, and patellar cartilage) in magnetic resonance (MR) imaging is of great importance for knee radiographic osteoarthritis (OA) diagnostic…

Image and Video Processing · Electrical Eng. & Systems 2019-08-14 Chaowei Tan , Zhennan Yan , Shaoting Zhang , Kang Li , Dimitris N. Metaxas

In recent years the NHS has been having increased difficulty seeing all low-risk patients, this includes but not limited to suspected osteoarthritis (OA) patients. To help address the increased waiting lists and shortages of staff, we…

Computer Vision and Pattern Recognition · Computer Science 2023-04-27 Kai Armstrong , Lei Zhang , Yan Wen , Alexander P. Willmott , Paul Lee , Xujioing Ye

Conventional inclusion criteria used in osteoarthritis clinical trials are not very effective in selecting patients who would benefit from a therapy being tested. Typically majority of selected patients show no or limited disease…

Objective: To assess the ability of imaging-based deep learning to predict radiographic patellofemoral osteoarthritis (PFOA) from knee lateral view radiographs. Design: Knee lateral view radiographs were extracted from The Multicenter…

Computer Vision and Pattern Recognition · Computer Science 2021-01-13 Neslihan Bayramoglu , Miika T. Nieminen , Simo Saarakkala

Bone marrow lesions (BMLs) are critical indicators of knee osteoarthritis (OA). Since they often appear as small, irregular structures with indistinguishable edges in knee magnetic resonance images (MRIs), effective detection of BMLs in MRI…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Shihua Qin , Ming Zhang , Juan Shan , Taehoon Shin , Jonghye Woo , Fangxu Xing

Magnetic Resonance Imaging (MRI) is a widely-accepted imaging technique for knee injury analysis. Its advantage of capturing knee structure in three dimensions makes it the ideal tool for radiologists to locate potential tears in the knee.…

Image and Video Processing · Electrical Eng. & Systems 2020-10-01 Chen-Han Tsai , Nahum Kiryati , Eli Konen , Iris Eshed , Arnaldo Mayer

Knee osteoarthritis (KOA) is a widespread condition that can cause chronic pain and stiffness in the knee joint. Early detection and diagnosis are crucial for successful clinical intervention and management to prevent severe complications,…

Computer Vision and Pattern Recognition · Computer Science 2023-07-11 Aymen Sekhri , Marouane Tliba , Mohamed Amine Kerkouri , Yassine Nasser , Aladine Chetouani , Alessandro Bruno , Rachid Jennane

Osteosarcoma is the most common primary bone cancer, mainly affecting the youngest and oldest populations. Its detection at early stages is crucial to reduce the probability of developing bone metastasis. In this context, accurate and fast…

Cartilage degeneration in joints causing pain and various types of knee problems is a serious problem-affecting people in all ages. Degenerated articular cartilage is also known as a central hallmark of osteoarthritis, which is a complex…

Applied Physics · Physics 2019-12-16 Abhishek Ranjan , Chengxiang peng , Anowarul Habib , Sanat Wagle , Frank Melandso

A fully-automated deep learning algorithm matched performance of radiologists in assessment of knee osteoarthritis severity in radiographs using the Kellgren-Lawrence grading system. To develop an automated deep learning-based algorithm…

Image and Video Processing · Electrical Eng. & Systems 2023-08-15 Albert Swiecicki , Nianyi Li , Jonathan O'Donnell , Nicholas Said , Jichen Yang , Richard C. Mather , William A. Jiranek , Maciej A. Mazurowski

We present a fully automated learning-based approach for segmenting knee cartilage in the presence of osteoarthritis (OA). The algorithm employs a hierarchical set of two random forest classifiers. The first is a neighborhood approximation…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Satyananda Kashyap , Ipek Oguz , Honghai Zhang , Milan Sonka

Chronic Kidney Disease (CKD) constitutes a major global medical burden, marked by the gradual deterioration of renal function, which results in the impaired clearance of metabolic waste and disturbances in systemic fluid homeostasis. Owing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Anas Bin Ayub , Nilima Sultana Niha , Md. Zahurul Haque

Knee osteoarthritis is a degenerative joint disease that induces chronic pain and disability. Bone morphological analysis is a promising tool to understand the mechanical aspect of this disorder. This study proposes a 2D bone morphological…

Image and Video Processing · Electrical Eng. & Systems 2024-03-14 Yun Xin Teoh , Alice Othmani , Siew Li Goh , Juliana Usman , Khin Wee Lai