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We describe a new approach to automated Glaucoma detection in 3D Spectral Domain Optical Coherence Tomography (OCT) optic nerve scans. First, we gathered a unique and diverse multi-ethnic dataset of OCT scans consisting of glaucoma and…

Previous approaches using deep learning algorithms to classify glaucomatous damage on fundus photographs have been limited by the requirement for human labeling of a reference training set. We propose a new approach using spectral-domain…

Computer Vision and Pattern Recognition · Computer Science 2018-10-25 Felipe A. Medeiros , Alessandro A. Jammal , Atalie C. Thompson

Image fusion is a crucial technique in the field of computer vision, and its goal is to generate high-quality fused images and improve the performance of downstream tasks. However, existing fusion methods struggle to balance these two…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Hui Li , Congcong Bian , Zeyang Zhang , Xiaoning Song , Xi Li , Xiao-Jun Wu

As current computing capabilities increase, modern machine learning and computer vision system tend to increase in complexity, mostly by means of larger models and advanced optimization strategies. Although often neglected, in many problems…

Image and Video Processing · Electrical Eng. & Systems 2024-06-07 Adrian Galdran , Miguel A. González Ballester

We propose a new method for training convolutional neural networks which integrates reinforcement learning along with supervised learning and use ti for transfer learning for classification of glaucoma from colored fundus images. The…

Image and Video Processing · Electrical Eng. & Systems 2021-05-19 Hardit Singh , Simarjeet Saini , Vasudevan Lakshminarayanan

Glaucoma is a leading cause of irreversible blindness. Accurate segmentation of the optic disc (OD) and cup (OC) from fundus images is beneficial to glaucoma screening and diagnosis. Recently, convolutional neural networks demonstrate…

Computer Vision and Pattern Recognition · Computer Science 2019-02-21 Shujun Wang , Lequan Yu , Xin Yang , Chi-Wing Fu , Pheng-Ann Heng

Ophthalmic images may contain identical-looking pathologies that can cause failure in automated techniques to distinguish different retinal degenerative diseases. Additionally, reliance on large annotated datasets and lack of knowledge…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Sharif Amit Kamran , Khondker Fariha Hossain , Alireza Tavakkoli , Stewart Lee Zuckerbrod , Salah A. Baker

Deep learning and computer vision methods are nowadays predominantly used in the field of ophthalmology. In this paper, we present an attention-aided DenseNet-121 for classifying normal and glaucomatous eyes from fundus images. It involves…

Image and Video Processing · Electrical Eng. & Systems 2024-06-24 Soham Chakraborty , Ayush Roy , Payel Pramanik , Daria Valenkova , Ram Sarkar

Glaucoma is a severe eye disease that is known to deteriorate optic never fibers, causing cup size to increase, which could result in permanent loss of vision. Glaucoma is the second leading cause of blindness after cataract, but glaucoma…

Image and Video Processing · Electrical Eng. & Systems 2021-04-09 Maleeha Khalid Khan , Syed Muhammad Anwar

With the advancement of deep learning techniques, an increasing number of methods have been proposed for optic disc and cup (OD/OC) segmentation from the fundus images. Clinically, OD/OC segmentation is often annotated by multiple clinical…

Image and Video Processing · Electrical Eng. & Systems 2022-09-20 Junde Wu , Huihui Fang , Dalu Yang , Zhaowei Wang , Wenshuo Zhou , Fangxin Shang , Yehui Yang , Yanwu Xu

Objective: To develop an explainable multimodal large language model (MM-LLM) that (1) screens optic nerve head (ONH) OCT circle scans for quality and (2) generates structured clinical reports that include glaucoma diagnosis and sector-wise…

GAMMA Challenge is organized to encourage the AI models to screen the glaucoma from a combination of 2D fundus image and 3D optical coherence tomography volume, like the ophthalmologists.

Image and Video Processing · Electrical Eng. & Systems 2022-09-26 Junde Wu , Huihui Fang , Fei Li , Huazhu Fu , Yanwu Xu

Although unprecedented sensitivity and specificity values are reported, recent glaucoma detection deep learning models lack in decision transparency. Here, we propose a methodology that advances explainable deep learning in the field of…

Image and Video Processing · Electrical Eng. & Systems 2021-10-06 Ruben Hemelings , Bart Elen , João Barbosa-Breda , Matthew B. Blaschko , Patrick De Boever , Ingeborg Stalmans

Optical Coherence Tomography (OCT) is essential for diagnosing conditions such as glaucoma, diabetic retinopathy, and age-related macular degeneration. Accurate retinal layer segmentation enables quantitative biomarkers critical for…

Image and Video Processing · Electrical Eng. & Systems 2025-09-10 S M Asiful Islam Saky , Ugyen Tshering

The classification of medical images is a pivotal aspect of disease diagnosis, often enhanced by deep learning techniques. However, traditional approaches typically focus on unimodal medical image data, neglecting the integration of diverse…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Jun-En Ding , Chien-Chin Hsu , Chi-Hsiang Chu , Shuqiang Wang , Feng Liu

Since annotating medical images for segmentation tasks commonly incurs expensive costs, it is highly desirable to design an annotation-efficient method to alleviate the annotation burden. Recently, contrastive learning has exhibited a great…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Yixuan Wu , Jintai Chen , Jiahuan Yan , Yiheng Zhu , Danny Z. Chen , Jian Wu

We propose glaucoma lesion evaluation and analysis with multimodal imaging (GLEAM), the first publicly available tri-modal glaucoma dataset comprising scanning laser ophthalmoscopy fundus images, circumpapillary OCT images, and visual field…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Jiao Wang , Chi Liu , Yiying Zhang , Hongchen Luo , Zhifen Guo , Ying Hu , Ke Xu , Jing Zhou , Hongyan Xu , Ruiting Zhou , Man Tang

Multimodal ophthalmic imaging-based diagnosis integrates color fundus image with optical coherence tomography (OCT) to provide a comprehensive view of ocular pathologies. However, the uneven global distribution of healthcare resources often…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Qinkai Yu , Jianyang Xie , Yitian Zhao , Cheng Chen , Lijun Zhang , Liming Chen , Jun Cheng , Lu Liu , Yalin Zheng , Yanda Meng

Medical image segmentation is a critical yet challenging task, primarily due to the difficulty of obtaining extensive datasets of high-quality, expert-annotated images. Contrastive learning presents a potential but still problematic…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Shuang Zeng , Lei Zhu , Xinliang Zhang , Hangzhou He , Yanye Lu

Existing multi-modal learning methods on fundus and OCT images mostly require both modalities to be available and strictly paired for training and testing, which appears less practical in clinical scenarios. To expand the scope of clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Lehan Wang , Chongchong Qi , Chubin Ou , Lin An , Mei Jin , Xiangbin Kong , Xiaomeng Li