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We provide a new computationally-efficient class of estimators for risk minimization. We show that these estimators are robust for general statistical models: in the classical Huber epsilon-contamination model and in heavy-tailed settings.…

Machine Learning · Statistics 2018-04-23 Adarsh Prasad , Arun Sai Suggala , Sivaraman Balakrishnan , Pradeep Ravikumar

Unraveling the co-expression of genes across studies enhances the understanding of cellular processes. Inferring gene co-expression networks from transcriptome data presents many challenges, including spurious gene correlations, sample…

Machine Learning · Statistics 2024-10-01 Teodora Pandeva , Martijs Jonker , Leendert Hamoen , Joris Mooij , Patrick Forré

A number of approaches have dealt with statistical assessment of self-similarity, and many of those are based on multiscale concepts. Most rely on certain distributional assumptions which are usually violated by real data traces, often…

Methodology · Statistics 2022-01-25 Erin K. Hamilton , Seonghye Jeon , Pepa Ramirez Cobo , Kichun Sky Lee , Brani Vidakovic

An important goal in cancer research is the survival prognosis of a patient based on a minimal panel of genomic and molecular markers such as genes or proteins. Purely data-driven models without any biological knowledge can produce…

Methodology · Statistics 2025-10-02 Tobias Østmo Hermansen , Manuela Zucknick , Zhi Zhao

Undirected graphs can be used to describe matrix variate distributions. In this paper, we develop new methods for estimating the graphical structures and underlying parameters, namely, the row and column covariance and inverse covariance…

Machine Learning · Statistics 2014-05-26 Shuheng Zhou

The paper proposes a method for constructing a sparse estimator for the inverse covariance (concentration) matrix in high-dimensional settings. The estimator uses a penalized normal likelihood approach and forces sparsity by using a…

Statistics Theory · Mathematics 2008-06-26 Adam J. Rothman , Peter J. Bickel , Elizaveta Levina , Ji Zhu

In high dimensions we propose and analyze an aggregation estimator of the precision matrix for Gaussian graphical models. This estimator, called graphical Exponential Screening (gES), linearly combines a suitable set of individual…

Machine Learning · Statistics 2016-07-05 Zhe Liu

This paper considers covariance matrix estimation of tensor data under high dimensionality. A multi-bandable covariance class is established to accommodate the need for complex covariance structures of multi-layer lattices and general…

Methodology · Statistics 2026-01-13 Hao-Xuan Sun , Song Xi Chen , Yumou Qiu

Numerical nonlinear algebra is applied to maximum likelihood estimation for Gaussian models defined by linear constraints on the covariance matrix. We examine the generic case as well as special models (e.g. Toeplitz, sparse, trees) that…

Computation · Statistics 2020-10-07 Bernd Sturmfels , Sascha Timme , Piotr Zwiernik

We describe an efficient, scalable Gaussian boson sampler based on a classical description of squeezed quantum light and a deterministic model of single-photon detectors that click when the incident amplitude falls above a given threshold.…

Quantum Physics · Physics 2025-07-24 Sarvesh Raghuraman , Aditya Patwardhan , Brian La Cour

We consider robust covariance estimation with group symmetry constraints. Non-Gaussian covariance estimation, e.g., Tyler scatter estimator and Multivariate Generalized Gaussian distribution methods, usually involve non-convex minimization…

Machine Learning · Statistics 2013-06-19 Ilya Soloveychik , Ami Wiesel

Cancer is a complex disease that provides various types of information depending on the scale of observation. While most tumor diagnostics are performed by observing histopathological slides, radiology images should yield additional…

Image and Video Processing · Electrical Eng. & Systems 2020-10-07 Marvin Lerousseau , Eric Deutsh , Nikos Paragios

This work is motivated by multimodality breast cancer imaging data, which is quite challenging in that the signals of discrete tumor-associated microvesicles (TMVs) are randomly distributed with heterogeneous patterns. This imposes a…

Machine Learning · Statistics 2019-03-22 Xiwei Tang , Xuan Bi , Annie Qu

We propose a residual randomization procedure designed for robust Lasso-based inference in the high-dimensional setting. Compared to earlier work that focuses on sub-Gaussian errors, the proposed procedure is designed to work robustly in…

Methodology · Statistics 2021-08-20 Y. Samuel Wang , Si Kai Lee , Panos Toulis , Mladen Kolar

We propose a method for high dimensional multivariate regression that is robust to random error distributions that are heavy-tailed or contain outliers, while preserving estimation accuracy in normal random error distributions. We extend…

Methodology · Statistics 2025-03-05 Mayu Hiraishi , Kensuke Tanioka , Hiroshi Yadohisa

The use of massive survival data has become common in survival analysis. In this study, a subsampling algorithm is proposed for the Cox proportional hazards model with time-dependent covariates when the sample is extraordinarily large but…

Computation · Statistics 2023-02-07 Nan Qiao , Wangcheng Li , Feng Xiao , Cunjie Lin , Yong Zhou

In this paper, we propose a Bayesian Graphical LASSO for correlated countable data and apply it to spatial crime data. In the proposed model, we assume a Gaussian Graphical Model for the latent variables which dominate the potential risks…

Methodology · Statistics 2020-06-08 Sho Ichigozaki , Takahiro Kawashima , Hayaru Shouno

Cluster-randomized experiments are increasingly used to evaluate interventions in routine practice conditions, and researchers often adopt model-based methods with covariate adjustment in the statistical analyses. However, the validity of…

Methodology · Statistics 2023-12-08 Bingkai Wang , Chan Park , Dylan S. Small , Fan Li

Robust statistical inference often faces a severe computational-statistical gap when dealing with complex parameter spaces. We investigate minimax signal detection in the Gaussian sequence model under strong $\epsilon$-contamination, where…

Statistics Theory · Mathematics 2026-05-13 Yikun Li , Matey Neykov

While several Gaussian mixture models-based biclustering approaches currently exist in the literature for continuous data, approaches to handle discrete data have not been well researched. A multivariate Poisson-lognormal (MPLN) model-based…

Methodology · Statistics 2025-03-13 Caitlin Kral , Evan Chance , Ryan Browne , Sanjeena Subedi
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