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Molecular self-organization driven by concerted many-body interactions produces the ordered structures that define both inanimate and living matter. Understanding the physical mechanisms that govern the formation of molecular complexes and…

Chemical Physics · Physics 2023-07-21 Hendrik Jung , Roberto Covino , A Arjun , Peter G. Bolhuis , Gerhard Hummer

Turing instability in activator-inhibitor systems provides a paradigm of nonequilibrium pattern formation; it has been extensively investigated for biological and chemical processes. Turing pattern formation should furthermore be possible…

Adaptation and Self-Organizing Systems · Physics 2010-05-13 Hiroya Nakao , Alexander S. Mikhailov

Self-organization, the ability of a system of microscopically interacting entities to shape macroscopically ordered structures, is ubiquitous in Nature. Spatio-temporal patterns are abundantly observed in a large plethora of applications,…

Pattern Formation and Solitons · Physics 2019-06-17 Malbor Asllani , Timoteo Carletti , Duccio Fanelli , Philip K. Maini

The advances in understanding complex networks have generated increasing interest in dynamical processes occurring on them. Pattern formation in activator-inhibitor systems has been studied in networks, revealing differences from the…

Adaptation and Self-Organizing Systems · Physics 2015-06-09 Nikos E. Kouvaris , Shigefumi Hata , Albert Díaz-Guilera

Dynamic patterning of specific proteins is essential for the spatiotemporal regulation of many important intracellular processes in procaryotes, eucaryotes, and multicellular organisms. The emergence of patterns generated by interactions of…

Biological Physics · Physics 2018-05-11 Jacob Halatek , Fridtjof Brauns , Erwin Frey

This paper investigates pattern formation in reaction--diffusion systems with both diffusive and nondiffusive components, providing necessary and sufficient conditions for diffusion-driven instability (DDI) and establishing the existence of…

Analysis of PDEs · Mathematics 2026-05-07 Théo André , Szymon Cygan , Anna Marciniak-Czochra , Finn Münnich

Spatial self-organization emerges in distributed systems exhibiting local interactions when nonlinearities and the appropriate propagation of signals are at work. These kinds of phenomena can be modeled with different frameworks, typically…

Cell Behavior · Quantitative Biology 2016-11-23 Adriano Bonforti , Salva Duran-Nebreda , Raul Montañez , Ricard Solé

Despite simplicity, the synchronous cellular automaton [D.A. Young, Math. Biosci. 72, 51 (1984)] enables reconstructing basic features of patterns of skin. Our extended model allows studying the formatting of patterns and their temporal…

Cell Behavior · Quantitative Biology 2018-07-12 R. Piasecki , W. Olchawa , K. Smaga

Several mechanisms have been proposed to explain the spontaneous generation of self-organized patterns, hypothesised to play a role in the formation of many of the magnificent patterns observed in Nature. In several cases of interest, the…

Pattern Formation and Solitons · Physics 2025-10-22 Riccardo Muolo , Malbor Asllani , Duccio Fanelli , Philip K. Maini , Timoteo Carletti

The Turing patterning mechanism is believed to underly the formation of repetitive structures in development, such as zebrafish stripes and mammalian digits, but it has proved difficult to isolate the specific biochemical species…

Molecular Networks · Quantitative Biology 2018-03-22 Stephen Smith , Neil Dalchau

Symmetry-breaking instabilities play an important role in understanding the mechanisms underlying the diversity of patterns observed in nature, such as in Turing's reaction--diffusion theory, which connects cellular signalling and transport…

Pattern Formation and Solitons · Physics 2023-12-25 Andrew L. Krause , Eamonn A. Gaffney , Thomas Jun Jewell , Václav Klika , Benjamin J. Walker

Nonlinear instabilities are responsible for spontaneous pattern formation in a vast number of natural and engineered systems ranging from biology to galaxies build-up. We propose a new instability mechanism leading to pattern formation in…

Pattern Formation and Solitons · Physics 2016-01-20 A. M. Perego , N. Tarasov , D. V. Churkin , S. K. Turitsyn , K. Staliunas

Self-organization in natural and engineered systems causes the emergence of ordered spatio-temporal motifs. In presence of diffusive species, Turing theory has been widely used to understand the formation of such patterns on continuous…

Statistical Mechanics · Physics 2025-10-22 Marie Dorchain , Riccardo Muolo , Timoteo Carletti

We propose an artificial life framework aimed at facilitating the emergence of intelligent organisms. In this framework there is no explicit notion of an agent: instead there is an environment made of atomic elements. These elements contain…

Neural and Evolutionary Computing · Computer Science 2021-01-20 Karol Gregor , Frederic Besse

Reaction-diffusion (RD) mechanisms in chemical and biological systems can yield a variety of patterns that may be functionally important. We show that diffusive coupling through the inactivating component in a generic model of coupled…

Pattern Formation and Solitons · Physics 2013-05-30 Rajeev Singh , Sitabhra Sinha

This paper proposes a control theoretic framework to model and analyze the self-organized pattern formation of molecular concentrations in biomolecular communication networks, emerging applications in synthetic biology. In biomolecular…

Molecular Networks · Quantitative Biology 2019-01-08 Yutaka Hori , Hiroki Miyazako , Soichiro Kumagai , Shinji Hara

We performed an extensive numerical study of a two-dimensional reaction-diffusion system of the activator-inhibitor type in which domain patterns can form. We showed that both multidomain and labyrinthine patterns may form spontaneously as…

patt-sol · Physics 2016-09-08 C. B. Muratov , V. V. Osipov

We report a new mechanism of pattern formation in growing bistable systems coupled indirectly. A modified Fujita et. al. model is studied as an example of a reaction-diffusion system of nondiffusive activator and inhibitor molecules…

Pattern Formation and Solitons · Physics 2015-06-23 Dorjsuren Battogtokh

Self-organization is ubiquitous in nature and mind. However, machine learning and theories of cognition still barely touch the subject. The hurdle is that general patterns are difficult to define in terms of dynamical equations and…

Artificial Intelligence · Computer Science 2023-02-07 Danilo Vasconcellos Vargas , Tham Yik Foong , Heng Zhang

We explore pattern formation in an active fluid system involving two chemical species that regulate active stress: a fast-diffusing species ($A$) and a slow-diffusing species ($I$). The growth of species $A$ is modelled using a nonlinear…

Pattern Formation and Solitons · Physics 2026-05-26 Joydeep Das , Abhishek Chaudhuri , Sudeshna Sinha
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