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Confocal and multi-photon microscopy are widely used for in-vivo fluorescence imaging of biological tissues such as the brain, offering non-invasive access up to ~1 mm depth without major loss in performance. A recently-developed…

Image deblurring is an economic way to reduce certain degradations (blur and noise) in acquired images. Thus, it has become essential tool in high resolution imaging in many applications, e.g., astronomy, microscopy or computational…

Optimization and Control · Mathematics 2017-05-19 Rahul Mourya , André Ferrari , Rémi Flamary , Pascal Bianchi , Cédric Richard

Removing the noise and improving the visual quality of hyperspectral images (HSIs) is challenging in academia and industry. Great efforts have been made to leverage local, global or spectral context information for HSI denoising. However,…

Image and Video Processing · Electrical Eng. & Systems 2023-04-20 Haodong Pan , Feng Gao , Junyu Dong , Qian Du

Optic deconvolution in light microscopy (LM) refers to recovering the object details from images, revealing the ground truth of samples. Traditional explicit methods in LM rely on the point spread function (PSF) during image acquisition.…

Quantitative Methods · Quantitative Biology 2026-03-24 Rui Li , Mikhail Kudryashev , Artur Yakimovich

In recent literature there are plenty of works that combine handcrafted and learnable regularizers to solve inverse imaging problems. While this hybrid approach has demonstrated promising results, the motivation for combining handcrafted…

Computer Vision and Pattern Recognition · Computer Science 2025-05-23 Alexandros Gkillas , Dimitris Ampeliotis , Kostas Berberidis

Deep neural networks have emerged as effective tools for computational imaging including quantitative phase microscopy of transparent samples. To reconstruct phase from intensity, current approaches rely on supervised learning with training…

Image and Video Processing · Electrical Eng. & Systems 2020-01-28 Emrah Bostan , Reinhard Heckel , Michael Chen , Michael Kellman , Laura Waller

Deep learning methods have achieved impressive performance for multi-class medical image segmentation. However, they are limited in their ability to encode topological interactions among different classes (e.g., containment and exclusion).…

While convolutional neural networks (CNNs) and vision transformers (ViTs) have advanced medical image segmentation, they face inherent limitations such as local receptive fields in CNNs and high computational complexity in ViTs. This paper…

Image and Video Processing · Electrical Eng. & Systems 2025-04-02 Pooya Ashtari , Shahryar Noei , Fateme Nateghi Haredasht , Jonathan H. Chen , Giuseppe Jurman , Aleksandra Pizurica , Sabine Van Huffel

Fluorescence microscopy plays an important role in biomedical research. The depth-variant point spread function (PSF) of a fluorescence microscope produces low-quality images especially in the out-of-focus regions of thick specimens.…

Image and Video Processing · Electrical Eng. & Systems 2019-07-09 Da He , De Cai , Jiasheng Zhou , Jiajia Luo , Sung-Liang Chen

The most ubiquitous form of computational aberration correction for microscopy is deconvolution. However, deconvolution relies on the assumption that the point spread function is the same across the entire field-of-view. This assumption is…

Image and Video Processing · Electrical Eng. & Systems 2025-04-30 Amit Kohli , Anastasios N. Angelopoulos , David McAllister , Esther Whang , Sixian You , Kyrollos Yanny , Federico M. Gasparoli , Bo-Jui Chang , Reto Fiolka , Laura Waller

Recent advances in transformer-based models have drawn attention to exploring these techniques in medical image segmentation, especially in conjunction with the U-Net model (or its variants), which has shown great success in medical image…

Image and Video Processing · Electrical Eng. & Systems 2021-10-22 Xiangyi Yan , Hao Tang , Shanlin Sun , Haoyu Ma , Deying Kong , Xiaohui Xie

Deconvolution microscopy has been extensively used to improve the resolution of the widefield fluorescent microscopy. Conventional approaches, which usually require the point spread function (PSF) measurement or blind estimation, are…

Machine Learning · Computer Science 2019-04-08 Sungjun Lim , Sang-Eun Lee , Sunghoe Chang , Jong Chul Ye

Convolutional blocks have played a crucial role in advancing medical image segmentation by excelling in dense prediction tasks. However, their inability to effectively capture long-range dependencies has limited their performance.…

Image and Video Processing · Electrical Eng. & Systems 2026-03-17 Siddhartha Mallick , Aayushman Ghosh , Jayanta Paul , Jaya Sil

Current medical image classification efforts mainly aim for higher average performance, often neglecting the balance between different classes. This can lead to significant differences in recognition accuracy between classes and obvious…

Image and Video Processing · Electrical Eng. & Systems 2024-06-26 Peng Huang , Shu Hu , Bo Peng , Jiashu Zhang , Xi Wu , Xin Wang

Image analysis using more than one modality (i.e. multi-modal) has been increasingly applied in the field of biomedical imaging. One of the challenges in performing the multimodal analysis is that there exist multiple schemes for fusing the…

Computer Vision and Pattern Recognition · Computer Science 2018-06-19 Zhe Guo , Xiang Li , Heng Huang , Ning Guo , Quanzheng Li

Deep neural networks have been developed drawing inspiration from the brain visual pathway, implementing an end-to-end approach: from image data to video object classes. However building an fMRI decoder with the typical structure of…

Machine Learning · Statistics 2017-01-10 Michele Svanera , Sergio Benini , Gal Raz , Talma Hendler , Rainer Goebel , Giancarlo Valente

Multi-modality image fusion aims at fusing modality-specific (complementarity) and modality-shared (correlation) information from multiple source images. To tackle the problem of the neglect of inter-feature relationships, high-frequency…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Xiaoli Zhang , Liying Wang , Libo Zhao , Xiongfei Li , Siwei Ma

Humans can robustly learn novel visual concepts even when images undergo various deformations and lose certain information. Mimicking the same behavior and synthesizing deformed instances of new concepts may help visual recognition systems…

Computer Vision and Pattern Recognition · Computer Science 2019-07-19 Zitian Chen , Yanwei Fu , Yu-Xiong Wang , Lin Ma , Wei Liu , Martial Hebert

Deep clustering has shown its promising capability in joint representation learning and clustering via deep neural networks. Despite the significant progress, the existing deep clustering works mostly utilize some distribution-based…

Computer Vision and Pattern Recognition · Computer Science 2023-10-18 Yuankun Xu , Dong Huang , Chang-Dong Wang , Jian-Huang Lai

Audio-visual speech enhancement system is regarded to be one of promising solutions for isolating and enhancing speech of desired speaker. Conventional methods focus on predicting clean speech spectrum via a naive convolution neural network…

Audio and Speech Processing · Electrical Eng. & Systems 2022-09-28 Xinmeng Xu , Jianjun Hao