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Computable estimates for the error of finite element discretisations of parabolic problems in the $L^\infty(0,T; L^2)$ norm are developed, which exhibit constant effectivities (the ratio of the estimated error to the true error) with…

Numerical Analysis · Mathematics 2018-03-09 Oliver J. Sutton

Cardiac digital twins provide a physics and physiology informed framework to deliver predictive and personalized medicine. However, high-fidelity multi-scale cardiac models remain a barrier to adoption due to their extensive computational…

Numerical Analysis · Mathematics 2023-06-09 Matteo Salvador , Marina Strocchi , Francesco Regazzoni , Luca Dede' , Steven Niederer , Alfio Quarteroni

We study the performance of first- and second-order optimization methods for l1-regularized sparse least-squares problems as the conditioning of the problem changes and the dimensions of the problem increase up to one trillion. A rigorously…

Optimization and Control · Mathematics 2015-12-16 Kimon Fountoulakis , Jacek Gondzio

Data-driven surrogate models can significantly accelerate the simulation of continuous dynamical systems, yet the step-wise accumulation of errors during autoregressive time-stepping often leads to spectral blow-up and unphysical…

Machine Learning · Computer Science 2026-03-19 Fengxiang Nie , Yasuhiro Suzuki

A well-known diagnostic imaging modality, termed ultrasound tomography, was quickly developed for the detection of very small tumors whose sizes are smaller than the wavelength of the incident pressure wave without ionizing radiation,…

Medical Physics · Physics 2015-08-05 Tran Quang-Huy , Tran Duc-Tan , Huynh Huu Tue , Nguyen Linh-Trung

Magnetic resonance imaging (MRI) is fundamental for the assessment of many diseases, due to its excellent tissue contrast characterization. This is based on quantitative techniques, such as T1 , T2 , and T2* mapping. Quantitative MRI…

We unify and extend the semigroup and the PDE approaches to stochastic maximal regularity of time-dependent semilinear parabolic problems with noise given by a cylindrical Brownian motion. We treat random coefficients that are only…

Analysis of PDEs · Mathematics 2019-02-12 Pierre Portal , Mark Veraar

In image denoising (IDN) processing, the low-rank property is usually considered as an important image prior. As a convex relaxation approximation of low rank, nuclear norm based algorithms and their variants have attracted significant…

Image and Video Processing · Electrical Eng. & Systems 2020-04-03 Yanwei Zhao , Ping Yang , Qiu Guan , Jianwei Zheng , Wanliang Wang

In this paper, we propose Plane Wave Elastography (PWE), a novel ultrasound shear wave elastography (SWE) approach. Currently, commercial methods for SWE rely on directional filtering based on the prior knowledge of the wave propagation…

Medical Physics · Physics 2021-08-11 Reza Khodayi-mehr , Matthew W. Urban , Michael M. Zavlanos , Wilkins Aquino

The purpose of this study is to develop a computer-aided diagnosis system for classifying benign and malignant lung lesions, and to assist physicians in real-time analysis of radial probe endobronchial ultrasound (EBUS) videos. During the…

Image and Video Processing · Electrical Eng. & Systems 2023-05-09 Ching-Kai Lin , Chin-Wen Chen , Yun-Chien Cheng

LSTD is a popular algorithm for value function approximation. Whenever the number of features is larger than the number of samples, it must be paired with some form of regularization. In particular, L1-regularization methods tend to perform…

Machine Learning · Computer Science 2012-07-03 Matthieu Geist , Bruno Scherrer , Alessandro Lazaric , Mohammad Ghavamzadeh

Inspired by the combinatorial algebraic approach proposed by Dhurandhar {\it et al.}, we propose two novel classes of second-generation time-delay interferometry (TDI) solutions and their further generalization. The primary strategy of the…

Instrumentation and Methods for Astrophysics · Physics 2023-07-19 Wei-Liang Qian , Pan-Pan Wang , Zhang-Qi Wu , Cheng-Gang Shao , Bin Wang , Rui-Hong Yue

End-to-end deep learning has achieved impressive results but remains limited by its reliance on large labeled datasets, poor generalization to unseen scenarios, and growing computational demands. In contrast, classical optimization methods…

Machine Learning · Computer Science 2025-08-19 Gal Lifshitz , Shahar Zuler , Ori Fouks , Dan Raviv

Accurately predicting the long-term evolution of turbulence is crucial for advancing scientific understanding and optimizing engineering applications. However, existing deep learning methods face significant bottlenecks in long-term…

Machine Learning · Computer Science 2025-11-20 Hao Wu , Yuan Gao , Chang Liu , Fan Xu , Fan Zhang , Zhihong Zhu , Yuqi Li , Xian Wu , Yuxuan Liang , Li Liu , Qingsong Wen , Kun Wang , Yu Zheng , Xiaomeng Huang

Understanding 3D fundamental processes is crucial for academic and industrial applications. Nowadays, X-ray time-resolved tomography, or tomoscopy, is a leading technique for in-situ and operando 4D (3D+time) characterization. Despite its…

We introduce a novel formulation for curvature regularization by penalizing normal curvatures from multiple directions. This total normal curvature regularization is capable of producing solutions with sharp edges and precise isotropic…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Tianle Lu , Ke Chen , Yuping Duan

Stiff dynamical systems present a challenge for machine-learning reduced-order models (ML-ROMs), as explicit time integration becomes unstable in stiff regimes while implicit integration within learning loops is computationally expensive…

Machine Learning · Computer Science 2026-03-19 Joe Standridge , Daniel Livescu , Paul Cizmas

Self-supervised image denoising techniques emerged as convenient methods that allow training denoising models without requiring ground-truth noise-free data. Existing methods usually optimize loss metrics that are calculated from multiple…

In the study of shapes of human organs using computational anatomy, variations are found to arise from inter-subject anatomical differences, disease-specific effects, and measurement noise. This paper introduces a stochastic model for…

Computer Vision and Pattern Recognition · Computer Science 2016-12-19 Alexis Arnaudon , Darryl D. Holm , Akshay Pai , Stefan Sommer

Modelling deformation of anatomical objects observed in medical images can help describe disease progression patterns and variations in anatomy across populations. We apply a stochastic generalisation of the Large Deformation Diffeomorphic…

Statistics Theory · Mathematics 2018-12-14 Line Kühnel , Alexis Arnaudon , Tom Fletcher , Stefan Sommer
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