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I present three types of applications of generalized additive models (GAMs) to COVID-19 mortality rates in the US for the purpose of advancing methods to document inequities with respect to which communities suffered disproportionate…

Applications · Statistics 2022-12-01 Christian Testa

To capture the death rates and strong weekly, biweekly and probably monthly patterns in the Canada COVID-19, we utilize the generalized additive models in the absence of direct statistically based measurement of infection rates. By…

Applications · Statistics 2020-08-04 Farzali Izadi

While COVID-19 has resulted in a significant increase in global mortality rates, the impact of the pandemic on mortality from other causes remains uncertain. To gain insight into the broader effects of COVID-19 on various causes of death,…

Applications · Statistics 2024-09-05 Wei Zhang , Antonietta Mira , Ernst C. Wit

The COVID-19 pandemic prompted a surge in computational models to simulate disease dynamics and guide interventions. Agent-based models (ABMs) are well-suited to capture population and environmental heterogeneity, but their rapid deployment…

Background: Seasonal influenza causes a substantial burden on healthcare services over the winter period when these systems are already under pressure. Policies during the COVID-19 pandemic supressed the transmission of season influenza,…

Hospitalisations from COVID-19 with Omicron sub-lineages have put a sustained pressure on the English healthcare system. Understanding the expected healthcare demand enables more effective and timely planning from public health. We collect…

Epidemic models describe the evolution of a communicable disease over time. These models are often modified to include the effects of interventions (control measures) such as vaccination, social distancing, school closings etc. Many such…

Methodology · Statistics 2026-01-27 Heejong Bong , Valérie Ventura , Larry Wasserman

We propose a general Bayesian approach to modeling epidemics such as COVID-19. The approach grew out of specific analyses conducted during the pandemic, in particular an analysis concerning the effects of non-pharmaceutical interventions…

Applications · Statistics 2021-01-01 Samir Bhatt , Neil Ferguson , Seth Flaxman , Axel Gandy , Swapnil Mishra , James A. Scott

Pandemic(epidemic) modeling, aiming at disease spreading analysis, has always been a popular research topic especially following the outbreak of COVID-19 in 2019. Some representative models including SIR-based deep learning prediction…

Machine Learning · Computer Science 2022-12-07 Danfeng Guo , Zijie Huang , Junheng Hao , Yizhou Sun , Wei Wang , Demetri Terzopoulos

Deployment of machine learning models in real high-risk settings (e.g. healthcare) often depends not only on the model's accuracy but also on its fairness, robustness, and interpretability. Generalized Additive Models (GAMs) are a class of…

Machine Learning · Computer Science 2022-03-17 Chun-Hao Chang , Rich Caruana , Anna Goldenberg

We address the problem of modeling constrained hospital resources in the midst of the COVID-19 pandemic in order to inform decision-makers of future demand and assess the societal value of possible interventions. For broad applicability, we…

Generalized additive models (GAMs) provide a way to blend parametric and non-parametric (function approximation) techniques together, making them flexible tools suitable for many modeling problems. For instance, GAMs can be used to…

Methodology · Statistics 2023-03-07 Antti Solonen , Stratos Staboulis

Epidemic models are invaluable tools to understand and implement strategies to control the spread of infectious diseases, as well as to inform public health policies and resource allocation. However, current modeling approaches have…

Methodology · Statistics 2026-05-12 Caitlin Ward , Rob Deardon , Alexandra M. Schmidt

We propose the novel use of a generative adversarial network (GAN) (i) to make predictions in time (PredGAN) and (ii) to assimilate measurements (DA-PredGAN). In the latter case, we take advantage of the natural adjoint-like properties of…

Machine Learning · Computer Science 2023-01-26 Vinicius L. S. Silva , Claire E. Heaney , Yaqi Li , Christopher C. Pain

This paper extends the canonical model of epidemiology, the SIRD model, to allow for time-varying parameters for real-time measurement and prediction of the trajectory of the Covid-19 pandemic. Time variation in model parameters is captured…

Econometrics · Economics 2023-02-01 Cem Cakmakli , Yasin Simsek

The spread of COVID-19 has coincided with the rise of Graph Neural Networks (GNNs), leading to several studies proposing their use to better forecast the evolution of the pandemic. Many such models also include Long Short Term Memory (LSTM)…

Machine Learning · Computer Science 2021-08-24 Nathan Sesti , Juan Jose Garau-Luis , Edward Crawley , Bruce Cameron

Nonlinear relationships between covariates and a response variable of interest are frequently encountered in animal science research. Within statistical models, these nonlinear effects have, traditionally, been handled using a range of…

Applications · Statistics 2025-10-28 Gavin L. Simpson

Neural networks have become a popular tool in predictive modelling, more commonly associated with machine learning and artificial intelligence than with statistics. Generalised Additive Models (GAMs) are flexible non-linear statistical…

Machine Learning · Statistics 2026-01-06 Jessica Doohan , Lucas Kook , Kevin Burke

The COVID-19 pandemic has emphasized the need for a robust understanding of epidemic models. Current models of epidemics are classified as either mechanistic or non-mechanistic: mechanistic models make explicit assumptions on the dynamics…

Machine Learning · Statistics 2022-01-14 Arnab Sarker , Ali Jadbabaie , Devavrat Shah

Intercity travel is one of the most important parameters for combating a pandemic. The ongoing COVID-19 pandemic has resulted in different computational studies involving intercity connections. In this study, the effects of intercity…

Physics and Society · Physics 2025-02-18 Emir Baysazan , A. Nihat Berker , Hasan Mandal , Hakan Kaygusuz
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