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We model intracellular regulatory dynamics with threshold-type state-dependent delay and investigate the effect of the state-dependent diffusion time. A general model which is an extension of the classic differential equation models with…

Dynamical Systems · Mathematics 2018-03-13 Qingwen Hu

Many biological processes are supported by special molecules, called motor proteins or molecular motors, that transport cellular cargoes along linear protein filaments and can reversibly associate to their tracks. Stimulated by these…

Statistical Mechanics · Physics 2021-11-17 Akriti Jindal , Anatoly B. Kolomeisky , Arvind Kumar Gupta

We develop an inertial coupling method for modeling the dynamics of point-like 'blob' particles immersed in an incompressible fluid, generalizing previous work for compressible fluids. The coupling consistently includes excess (positive or…

Soft Condensed Matter · Physics 2015-08-06 F. Balboa Usabiaga , R. Delgado-Buscalioni , B. E. Griffith , A. Donev

We propose a discrete analogue for the boundary local time of reflected diffusions in bounded Lipschitz domains. This discrete analogue, called the discrete local time, can be effectively simulated in practice and is obtained pathwise from…

Probability · Mathematics 2021-01-12 Wai-Tong Louis Fan

We consider the stability of position control of traveling waves in reaction-diffusion system as proposed in {[}J. L\"ober, H. Engel, arXiv:1304.2327{]}. Instead of analyzing the controlled reaction-diffusion system, stability is studied on…

Pattern Formation and Solitons · Physics 2014-06-16 Jakob Löber

Aggregation-diffusion equations are foundational tools for modelling biological aggregations. Their principal use is to link the collective movement mechanisms of organisms to their emergent space use patterns in a concrete mathematical…

Populations and Evolution · Quantitative Biology 2025-04-16 Jonathan R. Potts

We study a cellular automaton model, which allows diffusion of energy (or equivalently any other physical quantities such as mass of a particular compound) at every lattice site after each timestep. Unit amount of energy is randomly added…

Condensed Matter · Physics 2009-10-22 T. C. Chan , H. F. Chau , K. S. Cheng

Encounter-based models of diffusion provide a probabilistic framework for analyzing the effects of a partially absorbing reactive surface, in which the probability of absorption depends upon the amount of surface-particle contact time.…

Statistical Mechanics · Physics 2023-07-05 Paul C Bressloff

An encounter-based approach consists in using the boundary local time as a proxy for the number of encounters between a diffusing particle and a target to implement various surface reaction mechanisms on that target. In this paper, we…

Statistical Mechanics · Physics 2023-10-03 Ziyad Benkhadaj , Denis S. Grebenkov

For a cell moving in hydrodynamic flow above a wall, translational and rotational degrees of freedom are coupled by the Stokes equation. In addition, there is a close coupling of convection and diffusion due to the position-dependent…

Cell Behavior · Quantitative Biology 2008-07-14 C. B. Korn , U. S. Schwarz

Spontaneous persistent motions driven by active processes play a central role to maintain the living cells far from equilibrium. In the majority of the research works, the steady state dynamics of an active system has been described in…

Statistical Mechanics · Physics 2020-07-01 Subhasish Chaki , Rajarshi Chakrabarti

A theoretical model for stratified epithelium is presented. The viscoelastic properties of the tissue is assumed to be dependent on the spatial distribution of proliferative and differentiated cells. Based on this assumption, a hydrodynamic…

Biological Physics · Physics 2016-06-08 Wei-Ting Yeh , Hsuan-Yi Chen

Advective trapping occurs when solute enters low velocity zones in heterogeneous porous media. Classical local modeling approaches combine the impact of slow advection and diffusion into a hydrodynamic dispersion coefficient and many…

Fluid Dynamics · Physics 2020-12-02 Juan J. Hidalgo , Insa Neuweiler , Marco Dentz

Stochastic interactions generically enhance self-diffusivity in living and biological systems, e.g. optimizing navigation strategies and controlling material properties of cellular tissues and bacterial aggregates. Despite this, the…

Soft Condensed Matter · Physics 2024-01-24 Henry Alston , Thibault Bertrand

Macroscopic properties and shapes of biological tissues depend on the remodelling of cell-cell junctions at the microscopic scale. We propose a theoretical framework that couples a vertex model of solid confluent tissues with the dynamics…

Soft Condensed Matter · Physics 2020-12-02 Clement Zankoc , Matej Krajnc

We show a probabilistic functional limit result for one-dimensional diffusion processes that are reflected at an elastic boundary which is a function of the reflection local time. Such processes are constructed as limits of a sequence of…

Probability · Mathematics 2019-06-27 Dirk Becherer , Todor Bilarev , Peter Frentrup

Diffusion with stochastic resetting, instantaneous returns of a diffusing particle to a reference point, creates a stationary probability distribution. The paradigm is extended here to a doubly stochastic protocol in which the resetting…

Statistical Mechanics · Physics 2025-10-01 Maxence Arutkin , Shlomi Reuveni

Mixing at the interface between a convection zone and an adjacent, stably-stratified layer plays a crucial role in shaping the structure and evolution of stars and planets. In this work, we present a suite of 2D and 3D Boussinesq…

Fluid Dynamics · Physics 2025-11-06 Bradley W. Hindman , J. R. Fuentes

Some quantities in the reaction-diffusion models from cellular biology or ecology depend on the spatial average of density functions instead of local density functions. We show that such nonlocal spatial average can induce instability of…

Analysis of PDEs · Mathematics 2020-02-03 Qingyan Shi , Junping Shi , Yongli Song

We consider an extension of the zero-range process to the case where the hop rate depends on the state of both departure and arrival sites. We recover the misanthrope and the target process as special cases for which the probability of the…

Statistical Mechanics · Physics 2014-03-05 M. R. Evans , B. Waclaw