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We consider a particle undergoing diffusion with stochastic resetting in a bounded domain $\calU\subset \R^d$ for $d=2,3$. The domain is perforated by a set of partially absorbing targets within which the particle may be absorbed at a rate…

Statistical Mechanics · Physics 2021-10-14 Paul C. Bressloff , Ryan D. Schumm

In this paper we use singular perturbation theory to solve the 2D narrow capture problem for a set of partially accessible targets $\calU_k$, $k=1,\ldots,N$, in a bounded domain $\Omega\subset \R^2$. In contrast to previous models of narrow…

Statistical Mechanics · Physics 2025-04-08 Paul C Bressloff

In this paper we analyze the narrow capture problem for a single Brownian particle diffusing in a three-dimensional (3D) bounded domain containing a set of small, spherical traps. The boundary surface of each trap is taken to be a…

Statistical Mechanics · Physics 2022-11-23 Paul C Bressloff

We revise the encounter-based approach to imperfect diffusion-controlled reactions, which employs the statistics of encounters between a diffusing particle and the reactive region to implement surface reactions. We extend this approach to…

Statistical Mechanics · Physics 2023-10-03 Denis S. Grebenkov

We consider steady-state diffusion in a bounded planar domain with multiple small targets on a smooth boundary. Using the method of matched asymptotic expansions, we investigate the competition of these targets for a diffusing particle and…

Analysis of PDEs · Mathematics 2025-11-18 Denis S. Grebenkov , Michael J. Ward

We develop an asymptotic analysis of target fluxes in the three-dimensional (3D) narrow capture problem. The latter concerns a diffusive search process in which the targets are much smaller than the size of the search domain. The small…

Statistical Mechanics · Physics 2020-11-18 Paul C Bressloff

In this paper we extend our recent work on two-dimensional (2D) diffusive search-and-capture processes with multiple small targets (narrow capture problems) by considering an asymptotic expansion of the Laplace transformed probability flux…

Statistical Mechanics · Physics 2021-04-28 Paul C Bressloff

We investigate the statistics of encounters of a diffusing particle with different subsets of the boundary of a confining domain. The encounters with each subset are characterized by the boundary local time on that subset. We extend a…

Statistical Mechanics · Physics 2021-10-14 Denis S. Grebenkov

We develop an encounter-based approach for describing restricted diffusion with a gradient drift towards a partially reactive boundary. For this purpose, we introduce an extension of the Dirichlet-to-Neumann operator and use its eigenbasis…

Chemical Physics · Physics 2022-10-10 Denis S. Grebenkov

In this paper we develop a hybrid version of the encounter-based approach to diffusion-mediated absorption at a reactive surface, which takes into account stochastic switching of a diffusing particle's conformational state. For simplicity,…

Statistical Mechanics · Physics 2022-09-21 Paul C. Bressloff

We investigate restricted diffusion in a bounded domain towards a small partially reactive target in three- and higher-dimensional spaces. We propose a simple explicit approximation for the principal eigenvalue of the Laplace operator with…

Statistical Mechanics · Physics 2022-10-10 Adrien Chaigneau , Denis S. Grebenkov

We consider the kinetics of the imperfect narrow escape problem, i.e. the time it takes for a particle diffusing in a confined medium of generic shape to reach and to be adsorbed by a small, imperfectly reactive patch embedded in the…

Statistical Mechanics · Physics 2023-05-11 T. Guérin , M. Dolgushev , O. Bénichou , R. Voituriez

In this paper, we investigate the effects of stochastic resetting on diffusion in $\R^d\backslash \calU$, where $\calU$ is a bounded obstacle with a partially absorbing surface $\partial \calU$. We begin by considering a Robin boundary…

Statistical Mechanics · Physics 2022-06-29 Paul C. Bressloff

The narrow escape problem consists of deriving the asymptotic expansion of the solution of a drift-diffusion equation with the Dirichlet boundary condition on a small absorbing part of the boundary and the Neumann boundary condition on the…

Analysis of PDEs · Mathematics 2010-03-12 Habib Ammari , Kostis Kalimeris , Hyeonbae Kang , Hyundae Lee

A probabilistic framework for studying single-particle diffusion in partially absorbing media has recently been developed in terms of an encounter-based approach. The latter computes the joint probability density (generalized propagator)…

Statistical Mechanics · Physics 2022-10-12 Paul C Bressloff

When a flux of Brownian particles is injected in a narrow window located on the surface of a bounded domain, these particles diffuse and can eventually escape through a cluster of narrow windows. At steady-state, we compute asymptotically…

Analysis of PDEs · Mathematics 2024-07-31 Frédéric Paquin-Lefebvre , David Holcman

In this chapter, we review our recent work on first passage time (FPT) problems for absorption by a target whose interface is semipermeable. For pedagogical reasons, we focus on a single Brownian particle searching for a single target in a…

Statistical Mechanics · Physics 2023-11-01 Paul C Bressloff

In this paper, we develop an encounter-based model of partial surface adsorption for fractional diffusion in a bounded domain. We take the probability of adsorption to depend on the amount of particle-surface contact time, as specified by a…

Statistical Mechanics · Physics 2023-03-21 Paul C Bressloff

In this paper we consider a multiparticle version of a recent probabilistic framework for studying diffusion-mediated surface reactions. The basic idea of the probabilistic approach is to consider the joint probability density or…

Statistical Mechanics · Physics 2022-10-19 Paul C Bressloff

In this paper we extend the encounter-based model of diffusion-mediated surface absorption to the case of an unbiased run-and-tumble particle (RTP) confined to a finite interval $[0,L]$ and switching between two constant velocity states…

Statistical Mechanics · Physics 2022-12-07 Paul C Bressloff
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