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Positron emission tomography (PET) is a cornerstone of modern radiology. The ability to detect cancer and metastases in whole body scans fundamentally changed cancer diagnosis and treatment. One of the main bottlenecks in the clinical…

Computer Vision and Pattern Recognition · Computer Science 2022-04-28 Ida Häggström , C. Ross Schmidtlein , Gabriele Campanella , Thomas J. Fuchs

In this work, we investigate the application of deep learning methods for computed tomography in the context of having a low-data regime. As motivation, we review some of the existing approaches and obtain quantitative results after…

Image and Video Processing · Electrical Eng. & Systems 2021-04-20 Daniel Otero Baguer , Johannes Leuschner , Maximilian Schmidt

List-mode positron emission tomography (PET) image reconstruction is an important tool for PET scanners with many lines-of-response and additional information such as time-of-flight and depth-of-interaction. Deep learning is one possible…

Medical Physics · Physics 2024-02-13 Kibo Ote , Fumio Hashimoto , Yuya Onishi , Takashi Isobe , Yasuomi Ouchi

Positron emission tomography(PET) image reconstruction is an ill-posed inverse problem and suffers from high level of noise due to limited counts received. Recently deep neural networks especially convolutional neural networks(CNN) have…

Image and Video Processing · Electrical Eng. & Systems 2022-10-25 Rui Hu , Huafeng Liu

Combined use of PET and dual-energy CT provides complementary information for multi-parametric imaging. PETenabled dual-energy CT combines a low-energy x-ray CT image with a high-energy &\gamma&-ray CT (GCT) image reconstructed from…

Medical Physics · Physics 2021-08-04 Siqi Li , Guobao Wang

Differentiable rendering has been widely adopted in computer graphics as a powerful approach to inverse problems, enabling efficient gradient-based optimization by differentiating the image formation process with respect to millions of…

Direct reconstruction methods have been developed to estimate parametric images directly from the measured PET sinograms by combining the PET imaging model and tracer kinetics in an integrated framework. Due to limited counts received,…

Image and Video Processing · Electrical Eng. & Systems 2021-06-22 Kuang Gong , Ciprian Catana , Jinyi Qi , Quanzheng Li

This paper addresses the problem of learning the impulse responses characterizing forward models by means of a regularized kernel-based Prediction Error Method (PEM). The common approach to accomplish that is to approximate the system with…

Optimization and Control · Mathematics 2024-09-20 Giulio Fattore , Marco Peruzzo , Giacomo Sartori , Mattia Zorzi

Low-dose computed tomography (LDCT) offers significant advantages in reducing the potential harm to human bodies. However, reducing the X-ray dose in CT scanning often leads to severe noise and artifacts in the reconstructed images, which…

Image and Video Processing · Electrical Eng. & Systems 2024-08-27 Ran An , Yinghui Zhang , Xi Chen , Lemeng Li , Ke Chen , Hongwei Li

Deep Neural Networks, particularly Convolutional Neural Networks (ConvNets), have achieved incredible success in many vision tasks, but they usually require millions of parameters for good accuracy performance. With increasing applications…

Computer Vision and Pattern Recognition · Computer Science 2022-03-30 Yuhuang Hu , Shih-Chii Liu

We develop and evaluate MlPET, a fast localized machine learning approach for probabilistic PET image analysis addressing the noise-resolution trade-off in conventional reconstructions. MlPET replaces computationally demanding Markov chain…

Medical Physics · Physics 2026-01-27 Thomas Mejer Hansen , Nana Christensen , Mikkel Vendelbo

The ability of deep image prior (DIP) to recover high-quality images from incomplete or corrupted measurements has made it popular in inverse problems in image restoration and medical imaging including magnetic resonance imaging (MRI).…

Computer Vision and Pattern Recognition · Computer Science 2024-02-09 Shijun Liang , Evan Bell , Qing Qu , Rongrong Wang , Saiprasad Ravishankar

In this paper, we explore a novel method for tomographic image reconstruction in the field of SPECT imaging. Deep Learning methodologies and more specifically deep convolutional neural networks (CNN) are employed in the new reconstruction…

Machine Learning · Computer Science 2020-10-20 Charalambos Chrysostomou , Loizos Koutsantonis , Christos Lemesios , Costas N. Papanicolas

Modern tomography involves gathering projection data from multiple directions and feeding them into a software algorithm for tomographic reconstruction. We focus our study on image reconstruction from Radon data in the setting of…

Numerical Analysis · Mathematics 2014-12-19 Maria Angela Narduzzo

Large high-quality medical image datasets are difficult to acquire but necessary for many deep learning applications. For positron emission tomography (PET), reconstructed image quality is limited by inherent Poisson noise. We propose a…

Deep image prior (DIP) has been successfully applied to positron emission tomography (PET) image restoration, enabling represent implicit prior using only convolutional neural network architecture without training dataset, whereas the…

Medical Physics · Physics 2024-04-23 Yuya Onishi , Fumio Hashimoto , Kibo Ote , Keisuke Matsubara , Masanobu Ibaraki

Reconstruction of PET images is an ill-posed inverse problem and often requires iterative algorithms to achieve good image quality for reliable clinical use in practice, at huge computational costs. In this paper, we consider the PET…

Computer Vision and Pattern Recognition · Computer Science 2017-04-25 Jieqing Jiao , Sebastien Ourselin

Dynamic positron emission tomography (PET) reconstruction often presents high noise due to the use of short duration frames to describe the kinetics of the radiotracer. Here we introduce a new method to calculate a kernel matrix to be used…

Medical Physics · Physics 2026-01-01 Alan Miranda , Steven Staelens

We present deformable unsupervised medical image registration using a randomly-initialized deep convolutional neural network (CNN) as regularization prior. Conventional registration methods predict a transformation by minimizing…

Image and Video Processing · Electrical Eng. & Systems 2019-08-05 Max-Heinrich Laves , Sontje Ihler , Tobias Ortmaier

One popular strategy for image denoising is to design a generalized regularization term that is capable of exploring the implicit prior underlying data observation. Convolutional neural networks (CNN) have shown the powerful capability to…

Image and Video Processing · Electrical Eng. & Systems 2019-10-22 Peng Liu , Xiaoxiao Zhou , Junyiyang Li , El Basha Mohammad D , Ruogu Fang