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A FLIP device gives cross-sectional area along the length of the esophagus and one pressure measurement, both as a function of time. Deducing mechanical properties of the esophagus including wall material properties, contraction strength,…

Functional luminal imaging probe (FLIP) is used to measure cross-sectional area (CSA) and pressure at sphincters. It consists of a catheter surrounded by a fluid filled cylindrical bag, closed on both ends. Plotting the pressure-CSA…

An understanding how neurological disorders lead to mechanical dysfunction of the esophagus requires knowledge of the neural circuit of the enteric nervous system. Historically, this has been elusive. Here, we present an empirically guided…

Neurons and Cognition · Quantitative Biology 2024-03-04 Guy Elisha , Sourav Halder , Xinyi Liu , Dustin A. Carlson , Peter J. Kahrilas , John E. Pandolfino , Neelesh A. Patankar

Blood pressure regulation is commonly addressed in terms of local mechanisms such as vascular resistance, compliance and neurohumoral control. However, the human vasculature encompasses multiple quasi-closed flow loops under both…

Medical Physics · Physics 2026-02-11 Arturo Tozzi

The stomach plays a central role in digestion through coordinated muscle contractions, known as gastric peristalsis, driven by slow-wave electrophysiology. Understanding this process is critical for treating motility disorders such as…

Computational Engineering, Finance, and Science · Computer Science 2025-12-15 Maire S. Henke , Sebastian Brandstaeter , Sebastian L. Fuchs , Roland C. Aydin , Alessio Gizzi , Christian J. Cyron

Convergent extension of epithelial tissue is a key motif of animal morphogenesis. On a coarse scale, cell motion resembles laminar fluid flow; yet in contrast to a fluid, epithelial cells adhere to each other and maintain the tissue layer…

Biological Physics · Physics 2024-10-04 Nikolas H. Claussen , Fridtjof Brauns , Boris I. Shraiman

In this paper, we investigate both experimentally and theoretically the dynamics of a liquid plug driven by a cyclic periodic forcing inside a cylindrical rigid capillary tube. First, it is shown that depending on the type of forcing (flow…

Fluid Dynamics · Physics 2018-02-14 S Signe Mamba , J C Magniez , F Zoueshtiagh , M Baudoin , S Mamba

Elastoviscoplastic (EVP) fluid flows are driven by a non-trivial interplay between the elastic, viscous, and plastic properties, which under certain conditions can transition the otherwise laminar flow into complex flow instabilities with…

Soft Condensed Matter · Physics 2025-08-14 Christopher S. From , Vedad Dzanic , Vahid Niasar , Emilie Sauret

An initial radial electric field, $E_r(0)$, in an axisymmetric tokamak, results in geodesic acoustic mode (GAM) oscillations. The GAMs Landau damp, resulting in a much smaller final residual electric field, $E_r(\infty)$, and accompanying…

Plasma Physics · Physics 2016-02-16 W. Sengupta , A. B. Hassam

A novel technique for Electroencephalogram (EEG) compression is proposed in this article. This technique models the intrinsic dependency inherent between the different EEG channels. It is based on dipole fitting that is usually used in…

Information Theory · Computer Science 2024-10-30 Hoda Daou , Fabrice Labeau

The sudden arrest of motion due to confinement is commonly observed via the clogging transition in the flow of particles through a constriction. We present results of a simple experiment to elucidate a similar transition in the…

Soft Condensed Matter · Physics 2020-04-07 Emily A. Hobbs , Alexander Christensen , Brian C. Utter

Airway mucus is a complex material with both viscoelastic and viscoplastic properties that vary with healthy and pathological lung conditions. In this study, the effects of these conditions on airway closure are examined in a model problem,…

Fluid Dynamics · Physics 2022-11-29 O. Erken , B. Fazla , F. Romanò , J. B. Grotberg , D. Izbassarov , M. Muradoglu

The inverse problem of inferring electrocardiogram (ECG) from photoplethysmogram (PPG) is an emerging research direction that combines the easy measurability of PPG and the rich clinical knowledge of ECG for long-term continuous cardiac…

Signal Processing · Electrical Eng. & Systems 2023-01-18 Xin Tian , Qiang Zhu , Yuenan Li , Min Wu

Fluid mechanical peristaltic transport through esophagus has been of concern in the paper. A mathematical model has been developed with an aim to study the peristaltic transport of a rheological fluid for arbitrary wave shapes and tube…

Fluid Dynamics · Physics 2012-12-17 J. C. Misra , S. Maiti

The left ventricular end-systolic pressure-volume relationship (ESPVr) is a key indicator of cardiac contractility. Despite its established importance, several studies suggested that the mechanical mode of contraction, such as isovolumetric…

Medical Physics · Physics 2024-11-12 Francesco Regazzoni , Corrado Poggesi , Cecilia Ferrantini

Internal haemorrhage, often leading to cardio-vascular arrest happens to be one of the prime sources of high fatality rates in mammals. We propose a simplistic model of fluid flow to specify the location of the haemorrhagic spots, which, if…

Soft Condensed Matter · Physics 2013-04-01 Amit K. Chattopadhyay , Shreekantha Sil

Two-dimensional (2D) hopper flow of disks has been extensively studied. Here, we investigate hopper flow of ellipses with aspect ratio $\alpha = 2$, and we contrast that behavior to the flow of disks. We use a quasi-2D hopper containing…

Soft Condensed Matter · Physics 2016-06-22 Junyao Tang , Robert P. Behringer

We have explored isotropically jammed states of semi-2D granular materials through cyclic compression. In each compression cycle, systems of either identical ellipses or bi-disperse disks, transition between jammed and unjammed states. We…

Soft Condensed Matter · Physics 2013-09-30 Somayeh Farhadi , Robert P Behringer , Alex Z Zhu

We examine computationally the two-dimensional flow of elastoviscoplastic (EVP) fluids around a cylinder symmetrically placed between two plates parallel to its axis. The Saramito-Herschel-Bulkley fluid model is solved via the finite-volume…

Fluid Dynamics · Physics 2025-01-14 Milad Mousavi , Yannis Dimakopoulos , John Tsamopoulos

In a previous paper, Oruba, Soward & Dormy (J.Fluid Mech., vol.818, 2017, pp.205-240) considered the primary quasi-steady geostrophic (QG) motion of a constant density fluid of viscosity $\nu$ that occurs during linear spin-down in a…

Fluid Dynamics · Physics 2020-03-18 L. Oruba , A. M. Soward , E. Dormy
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