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We present a new class of models for assessing the cell dynamics characterising muscular dystrophies. The proposed approach comprises a system of integro-differential equations for the statistical distributions, over a large patient cohort,…

Analysis of PDEs · Mathematics 2025-11-20 Tommaso Lorenzi , Horacio Tettamanti , Mattia Zanella

Multiple sclerosis (MS) is a progressive inflammatory and neurodegenerative disease of the central nervous system affecting over 2.5 million people globally. In-clinic six-minute walk test (6MWT) is a widely used objective measure to…

We present a phase field-based framework for modelling fatigue damage in Shape Memory Alloys (SMAs). The model combines, for the first time: (i) a generalised phase field description of fracture, incorporating multiple phase field…

Computational Engineering, Finance, and Science · Computer Science 2021-12-16 M. Simoes , C. Braithwaite , A. Makaya , E. Martínez-Pañeda

The paradigm that the primary amino acid sequence prescribes structure and thus function has for a long time been central to the understanding of protein science. Though the theory is supported by the behaviour of most structured proteins,…

Biological Physics · Physics 2022-12-19 Rickie Xian , Sarah Rauscher

We introduce a novel musculoskeletal model of a dog, procedurally generated from accurate 3D muscle meshes. Accompanying this model is a motion capture-based locomotion task compatible with a variety of control algorithms, as well as an…

Robotics · Computer Science 2025-07-01 Vittorio La Barbera , Steven Bohez , Leonard Hasenclever , Yuval Tassa , John R. Hutchinson

A common challenge in home-based rehabilitation is muscle compensation induced by pain or fatigue, where patients with weakened primary muscles recruit secondary muscle groups to assist their movement, causing issues such as delayed…

Signal Processing · Electrical Eng. & Systems 2025-08-26 Ming Xuan Chua , Shuhua Peng , Thanh Nho Do , Chun Hui Wang , Liao Wu

The modeling of cascading failure in power systems is difficult because of the many different mechanisms involved; no single model captures all of these mechanisms. Understanding the relative importance of these different mechanisms is an…

Physics and Society · Physics 2016-11-17 Jiajia Song , Eduardo Cotilla-Sanchez , Goodarz Ghanavati , Paul D. H. Hines

Head motion is a key determinant of motion comfort and differs substantially from seat motion due to seat and body compliance and dynamic postural stabilization. This paper compares different human body model fidelities to transmit seat…

Robotics · Computer Science 2025-09-11 Georgios Papaioannou , Raj Desai , Riender Happee

This research introduces a unified approach combining Automated Machine Learning (AutoML) with Explainable Artificial Intelligence (XAI) to predict fatigue strength in welded transverse stiffener details. It integrates expert-driven feature…

Computational Engineering, Finance, and Science · Computer Science 2025-11-07 Michael A. Kraus , Helen Bartsch

Robotic devices hold great potential for efficient and reliable assessment of neuromotor abnormalities in post-stroke patients. However, spasticity caused by stroke is still assessed manually in clinical settings. The limited and variable…

Robotics · Computer Science 2024-12-09 Hao Yu , Zebin Huang , Yutong Li , Xinliang Guo , Vincent Crocher , Ignacio Carlucho , Mustafa Suphi Erden

The paper presents a new stiffness modelling method for multi-chain parallel robotic manipulators with flexible links and compliant actuating joints. In contrast to other works, the method involves a FEA-based link stiffness evaluation and…

Robotics · Computer Science 2008-10-07 Anatoly Pashkevich , Damien Chablat , Philippe Wenger

Stress is a complex issue with wide-ranging physical and psychological impacts on human daily performance. Specifically, acute stress detection is becoming a valuable application in contextual human understanding. Two common approaches to…

Machine Learning · Computer Science 2022-03-21 Van-Tu Ninh , Manh-Duy Nguyen , Sinéad Smyth , Minh-Triet Tran , Graham Healy , Binh T. Nguyen , Cathal Gurrin

Motion sickness (MS) has long been a common complaint in road transportation. However, in the era of driving automation, MS has become an increasingly significant issue. The future intelligent vehicle is envisioned as a mobile space for…

Systems and Control · Electrical Eng. & Systems 2024-02-02 Daofei Li , Tingzhe Yu , Binbin Tang

This paper discusses the stability of an equilibrium point of an ordinary differential equation (ODE) arising from a feed-forward position control for a musculoskeletal system. The studied system has a link, a joint and two muscles with…

Dynamical Systems · Mathematics 2019-04-30 Takahiro Kosugi , Hitoshi Kino , Masaaki Goto , Yuki Matsutani

The development of accurate constitutive models for materials that undergo path-dependent processes continues to be a complex challenge in computational solid mechanics. Challenges arise both in considering the appropriate model assumptions…

Machine Learning · Computer Science 2023-02-22 Jan N. Fuhg , Craig M. Hamel , Kyle Johnson , Reese Jones , Nikolaos Bouklas

Due to the flexibility and adaptability of human, manual handling work is still very important in industry, especially for assembly and maintenance work. Well-designed work operation can improve work efficiency and quality; enhance safety,…

Robotics · Computer Science 2010-07-28 Liang Ma , Wei Zhang , Huanzhang Fu , Yang Guo , Damien Chablat , Fouad Bennis

Embodied agents in continuous control domains have had limited exposure to tasks allowing to explore musculoskeletal properties that enable agile and nimble behaviors in biological beings. The sophistication behind neuro-musculoskeletal…

Robotics · Computer Science 2022-06-07 Vittorio Caggiano , Huawei Wang , Guillaume Durandau , Massimo Sartori , Vikash Kumar

Neural networks are powerful models that solve a variety of complex real-world problems. However, the stochastic nature of training and large number of parameters in a typical neural model makes them difficult to evaluate via inspection.…

Machine Learning · Computer Science 2021-04-22 John Clemens

We propose four novel mathematical models, describing the microscopic mechanisms of force generation in the cardiac muscle tissue, which are suitable for multiscale numerical simulations of cardiac electromechanics. Such models are based on…

Subcellular Processes · Quantitative Biology 2021-01-27 Francesco Regazzoni , Luca Dedè , Alfio Quarteroni

In dynamic simulation of complete wheel loaders, one interesting aspect, specific for the working task, is the momentary power distribution between drive train and hydraulics, which is balanced by the operator. This paper presents the…

Computational Engineering, Finance, and Science · Computer Science 2011-08-30 Reno Filla , Allan Ericsson , Jan-Ove Palmberg