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Deep neural networks (DNNs) are widely studied in various applications. A DNN consists of layers of neurons that compute affine combinations, apply nonlinear operations, and produce corresponding activations. The rectified linear unit…

Machine Learning · Computer Science 2024-02-13 Navid Aftabi , Nima Moradi , Fatemeh Mahroo

This work introduces a framework to address the computational complexity inherent in Mixed-Integer Programming (MIP) models by harnessing the potential of deep learning. By employing deep learning, we construct problem-specific heuristics…

Optimization and Control · Mathematics 2024-05-13 Niki Triantafyllou , Maria M. Papathanasiou

We present an ideal mixed-integer programming (MIP) formulation for a rectified linear unit (ReLU) appearing in a trained neural network. Our formulation requires a single binary variable and no additional continuous variables beyond the…

Optimization and Control · Mathematics 2019-03-04 Ross Anderson , Joey Huchette , Christian Tjandraatmadja , Juan Pablo Vielma

Recent work has shown potential in using Mixed Integer Programming (MIP) solvers to optimize certain aspects of neural networks (NNs). However the intriguing approach of training NNs with MIP solvers is under-explored.…

Machine Learning · Computer Science 2023-04-03 Tómas Thorbjarnarson , Neil Yorke-Smith

We present strong mixed-integer programming (MIP) formulations for high-dimensional piecewise linear functions that correspond to trained neural networks. These formulations can be used for a number of important tasks, such as verifying…

Optimization and Control · Mathematics 2020-01-23 Ross Anderson , Joey Huchette , Will Ma , Christian Tjandraatmadja , Juan Pablo Vielma

We introduce a mixed integer program (MIP) for assigning importance scores to each neuron in deep neural network architectures which is guided by the impact of their simultaneous pruning on the main learning task of the network. By…

Machine Learning · Computer Science 2023-07-26 Mostafa ElAraby , Guy Wolf , Margarida Carvalho

In recent years, the integration of Machine Learning (ML) models with Operation Research (OR) tools has gained popularity across diverse applications, including cancer treatment, algorithmic configuration, and chemical process optimization.…

Machine Learning · Computer Science 2023-07-17 Matteo Cacciola , Antonio Frangioni , Andrea Lodi

This paper presents a unified mixed-integer programming framework for training sparse and interpretable neural networks. We develop exact formulations for both fully connected and convolutional architectures by modeling nonlinearities such…

Artificial Intelligence · Computer Science 2025-04-22 Masoud Ataei , Edrin Hasaj , Jacob Gipp , Sepideh Forouzi

One of the most common and universal problems in science is to investigate a function. The prediction can be made by an Artificial Neural Network (ANN) or a mathematical model. Both approaches have their advantages and disadvantages.…

Neural and Evolutionary Computing · Computer Science 2022-02-22 Szymon Buchaniec , Marek Gnatowski , Grzegorz Brus

Mixed-signal artificial neural networks (ANNs) that employ analog matrix-multiplication accelerators can achieve higher speed and improved power efficiency. Though analog computing is known to be susceptible to noise and device…

Signal Processing · Electrical Eng. & Systems 2021-07-01 Joseph Ulseth , Zheyuan Zhu , Guifang Li , Shuo Pang

Artificial Neural Networks (ANNs) have emerged as hot topics in the research community. Despite the success of ANNs, it is challenging to train and deploy modern ANNs on commodity hardware due to the ever-increasing model size and the…

Neural and Evolutionary Computing · Computer Science 2021-01-19 Shiwei Liu , Decebal Constantin Mocanu , Amarsagar Reddy Ramapuram Matavalam , Yulong Pei , Mykola Pechenizkiy

Mixed Integer Linear Programs (MILPs) are essential tools for solving planning and scheduling problems across critical industries such as construction, manufacturing, and logistics. However, their widespread adoption is limited by long…

Machine Learning · Computer Science 2025-06-10 Xiaoke Wang , Batuhan Altundas , Zhaoxin Li , Aaron Zhao , Matthew Gombolay

Global optimization of decision trees is a long-standing challenge in combinatorial optimization, yet such models play an important role in interpretable machine learning. Although the problem has been investigated for several decades, only…

Machine Learning · Computer Science 2026-02-03 Jiancheng Tu , Wenqi Fan , Zhibin Wu

The deployment of Artificial Neural Networks (ANNs) in safety-critical applications poses a number of new verification and certification challenges. In particular, for ANN-enabled self-driving vehicles it is important to establish…

Machine Learning · Computer Science 2017-07-06 Chih-Hong Cheng , Georg Nührenberg , Harald Ruess

Mixed-integer linear programming (MILP) is widely employed for modeling combinatorial optimization problems. In practice, similar MILP instances with only coefficient variations are routinely solved, and machine learning (ML) algorithms are…

Optimization and Control · Mathematics 2023-03-07 Qingyu Han , Linxin Yang , Qian Chen , Xiang Zhou , Dong Zhang , Akang Wang , Ruoyu Sun , Xiaodong Luo

Deep Neural Networks (DNNs) are very popular these days, and are the subject of a very intense investigation. A DNN is made by layers of internal units (or neurons), each of which computes an affine combination of the output of the units in…

Machine Learning · Computer Science 2017-12-19 Matteo Fischetti , Jason Jo

Mixed-integer linear programming (MILP), a widely used modeling framework for combinatorial optimization, are central to many scientific and engineering applications, yet remains computationally challenging at scale. Recent advances in deep…

Artificial Intelligence · Computer Science 2026-01-09 Peixin Huang , Yaoxin Wu , Yining Ma , Cathy Wu , Wen Song , Wei Zhang

Mixed-integer programming (MIP) technology offers a generic way of formulating and solving combinatorial optimization problems. While generally reliable, state-of-the-art MIP solvers base many crucial decisions on hand-crafted heuristics,…

Machine Learning · Computer Science 2022-05-31 Elias B. Khalil , Christopher Morris , Andrea Lodi

While Mixed-integer linear programming (MILP) is NP-hard in general, practical MILP has received roughly 100--fold speedup in the past twenty years. Still, many classes of MILPs quickly become unsolvable as their sizes increase, motivating…

Machine Learning · Computer Science 2023-05-29 Ziang Chen , Jialin Liu , Xinshang Wang , Jianfeng Lu , Wotao Yin

Mixed Integer programs (MIPs) are typically solved by the Branch-and-Bound algorithm. Recently, Learning to imitate fast approximations of the expert strong branching heuristic has gained attention due to its success in reducing the running…

Optimization and Control · Mathematics 2023-07-03 Sahil Manchanda , Sayan Ranu
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